4Q65
| Structure of the E. coli Peptide Transporter YbgH | 分子名称: | Dipeptide permease D | 著者 | Zhang, C, Zhao, Y, Mao, G, Liu, M, Wang, X. | 登録日 | 2014-04-21 | 公開日 | 2014-08-13 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of the E. coli peptide transporter YbgH. Structure, 22, 2014
|
|
5D6K
| PepT - CIM | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Di-or tripeptide:H+ symporter, ... | 著者 | Ma, P, Caffrey, M. | 登録日 | 2015-08-12 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The cubicon method for concentrating membrane proteins in the cubic mesophase. Nat Protoc, 12, 2017
|
|
8P6A
| |
5D58
| In meso in situ serial X-ray crystallography structure of the PepTSt-Ala-Phe complex at 100 K | 分子名称: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ALANINE, ... | 著者 | Huang, C.-Y, Olieric, V, Diederichs, K, Wang, M, Caffrey, M. | 登録日 | 2015-08-10 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures. Acta Crystallogr D Struct Biol, 72, 2016
|
|
5D59
| In meso X-ray crystallography structure of the PepTSt-Ala-Phe complex at 100 K | 分子名称: | (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ALANINE, ... | 著者 | Huang, C.-Y, Olieric, V, Wang, M, Caffrey, M. | 登録日 | 2015-08-10 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures. Acta Crystallogr D Struct Biol, 72, 2016
|
|
4TPJ
| Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | 分子名称: | ALA-ALA-ALA, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ... | 著者 | Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. | 登録日 | 2014-06-07 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
|
|
4TPH
| Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | 分子名称: | 3,5 DIBROMOTYROSINE, ALANINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Guettou, F, Quistgaard, E, Raba, M, Moberg, P, Low, C, Nordlund, P. | 登録日 | 2014-06-07 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.155 Å) | 主引用文献 | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
|
|
4TPG
| Selectivity mechanism of a bacterial homologue of the human drug peptide transporters PepT1 and PepT2 | 分子名称: | Ala-L-3-Br-Tyr-Ala, DODECYL-BETA-D-MALTOSIDE, Proton:oligopeptide symporter POT family, ... | 著者 | Guettou, F, Quistgaard, E.M, Raba, M, Moberg, P, Low, C, Nordlund, P. | 登録日 | 2014-06-07 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.91 Å) | 主引用文献 | Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2. Nat.Struct.Mol.Biol., 21, 2014
|
|
4IKX
| Crystal structure of peptide transporter POT (E310Q mutant) | 分子名称: | Di-tripeptide ABC transporter (Permease), OLEIC ACID, SULFATE ION | 著者 | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | 登録日 | 2012-12-28 | 公開日 | 2013-07-10 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4IKV
| Crystal structure of peptide transporter POT | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Di-tripeptide ABC transporter (Permease), OLEIC ACID, ... | 著者 | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | 登録日 | 2012-12-28 | 公開日 | 2013-07-10 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4IKZ
| Crystal structure of peptide transporter POT (E310Q mutant) in complex with alafosfalin | 分子名称: | Di-tripeptide ABC transporter (Permease), N-[(1R)-1-phosphonoethyl]-L-alaninamide, SULFATE ION | 著者 | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | 登録日 | 2012-12-28 | 公開日 | 2013-07-10 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4IKY
| Crystal structure of peptide transporter POT (E310Q mutant) in complex with sulfate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Di-tripeptide ABC transporter (Permease), OLEIC ACID, ... | 著者 | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | 登録日 | 2012-12-28 | 公開日 | 2013-07-10 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4IKW
| Crystal structure of peptide transporter POT in complex with sulfate | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Di-tripeptide ABC transporter (Permease), OLEIC ACID, ... | 著者 | Doki, S, Kato, H.E, Ishitani, R, Nureki, O. | 登録日 | 2012-12-28 | 公開日 | 2013-07-10 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
7PMX
| HsPepT1 bound to Ala-Phe in the outward facing open conformation | 分子名称: | ALA-PHE, Solute carrier family 15 member 1 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-03 | 公開日 | 2021-10-20 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
|
|
7PMY
| HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation | 分子名称: | ALA-PHE, Solute carrier family 15 member 2 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-04 | 公開日 | 2021-10-20 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
|
|
7PMW
| HsPepT1 bound to Ala-Phe in the outward facing occluded conformation | 分子名称: | ALA-PHE, Solute carrier family 15 member 1 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-03 | 公開日 | 2021-10-20 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
|
|
7PN1
| Apo HsPepT1 in the outward facing open conformation | 分子名称: | Solute carrier family 15 member 1 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-04 | 公開日 | 2021-10-20 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
|
|
7Q0L
| Crystal structure of the peptide transporter YePEPT-K314A at 2.93 A | 分子名称: | Peptide transporter YePEPT | 著者 | Jeckelmann, J.M, Stauffer, M, Ilgue, H, Boggavarapu, R, Fotiadis, D. | 登録日 | 2021-10-15 | 公開日 | 2022-03-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | 主引用文献 | Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5, 2022
|
|
7Q0M
| Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A | 分子名称: | (2~{S})-2-[[(2~{S})-2-azanyl-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoyl]amino]-3-methyl-butanoic acid, Peptide transporter YePEPT, UNDECYL-MALTOSIDE | 著者 | Jeckelmann, J.M, Stauffer, M, Ilgue, H, Fotiadis, D. | 登録日 | 2021-10-15 | 公開日 | 2022-03-09 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5, 2022
|
|
4LEP
| Structural insights into substrate recognition in proton dependent oligopeptide transporters | 分子名称: | N-[(1R)-1-phosphonoethyl]-L-alaninamide, Proton:oligopeptide symporter POT family, ZINC ION | 著者 | Guettou, F, Quistgaard, E.M, Tresaugues, L, Moberg, P, Jegerschold, C, Zhu, L, Jong, A.J, Nordlund, P, Low, C. | 登録日 | 2013-06-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into substrate recognition in proton-dependent oligopeptide transporters. Embo Rep., 14, 2013
|
|
5OXM
| PepTSt in complex with dipeptide Asp-Glu | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ASPARTIC ACID, ... | 著者 | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | 登録日 | 2017-09-07 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
|
|
5OXK
| PepTSt in complex with dipeptide Ala-Gln | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | 著者 | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | 登録日 | 2017-09-07 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
|
|
5OXQ
| PepTSt in complex with HEPES (300 mM) | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | 登録日 | 2017-09-07 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.195 Å) | 主引用文献 | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
|
|
5OXN
| PepTSt in complex with dipeptide Phe-Ala | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ... | 著者 | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | 登録日 | 2017-09-07 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
|
|
5OXO
| PepTSt apo structure | 分子名称: | (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, CITRIC ACID, ... | 著者 | Martinez Molledo, M, Quistgaard, E.M, Loew, C. | 登録日 | 2017-09-07 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter. Structure, 26, 2018
|
|