PDB: 67 件ウェブページステータス検索Chemie searchBIRD

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1KHE	PEPCK complex with nonhydrolyzable GTP analog, MAD data 分子名称: MANGANESE (II) ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Phosphoenolpyruvate Carboxykinase, ... 著者 Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. 登録日 2001-11-29 公開日 2002-02-27 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHB	PEPCK complex with nonhydrolyzable GTP analog, native data 分子名称: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... 著者 Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. 登録日 2001-11-29 公開日 2002-02-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.854 Å) 主引用文献 Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHG	PEPCK 分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... 著者 Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. 登録日 2001-11-29 公開日 2002-02-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHF	PEPCK complex with PEP 分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... 著者 Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. 登録日 2001-11-29 公開日 2002-02-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1M51	PEPCK complex with a GTP-competitive inhibitor 分子名称: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... 著者 Foley, L.H, Wang, P, Dunten, P, Wertheimer, S.J. 登録日 2002-07-06 公開日 2003-09-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 X-ray Structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett., 13, 2003
1NHX	PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR 分子名称: 1,2-ETHANEDIOL, MANGANESE (II) ION, N-{4-[1-(2-FLUOROBENZYL)-3-BUTYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YLMETHYL]-PHENYL}-ACETAMIDE, ... 著者 Foley, L.H, Wang, P, Dunten, P, Ramsey, G, Gubler, M.-L, Wertheimer, S.J. 登録日 2002-12-19 公開日 2003-09-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett., 13, 2003
2FAF	The structure of chicken mitochondrial PEPCK. 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MANGANESE (II) ION, PENTAETHYLENE GLYCOL, ... 著者 Holyoak, T, Sullivan, S.M, Nowak, T. 登録日 2005-12-07 公開日 2006-06-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Insights into the Mechanism of PEPCK Catalysis Biochemistry, 45, 2006
2FAH	The structure of mitochondrial PEPCK, Complex with Mn and GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MALONIC ACID, MANGANESE (II) ION, ... 著者 Holyoak, T, Sullivan, S.M, Nowak, T. 登録日 2005-12-07 公開日 2006-06-27 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural Insights into the Mechanism of PEPCK Catalysis Biochemistry, 45, 2006
2GMV	PEPCK complex with a GTP-competitive inhibitor 分子名称: MANGANESE (II) ION, N-(4-{[3-BUTYL-1-(2-FLUOROBENZYL)-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL]METHYL}PHENYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE, PHOSPHOENOLPYRUVATE, ... 著者 Dunten, P. 登録日 2006-04-07 公開日 2007-05-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase. Bioorg.Med.Chem.Lett., 17, 2007
2QEW	Rat cytosolic PEPCK, in complex with manganese ion. 分子名称: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2007-06-26 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QF2	Rat cytosolic PEPCK in complex with oxaloacetic acid and GDP. 分子名称: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, OXALOACETATE ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2007-06-26 公開日 2007-08-28 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QEY	Rat cytosolic PEPCK in complex with GTP 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2007-06-26 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QF1	Rat cytosolic PEPCK in complex with oxaloacetic acid. 分子名称: MANGANESE (II) ION, OXALOACETATE ION, Phosphoenolpyruvate carboxykinase, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2007-06-26 公開日 2007-08-21 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QZY	The structure of chicken mitochondrial PEPCK in complex with PEP 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... 著者 Holyoak, T, Sullivan, S.M, Nowak, T. 登録日 2007-08-17 公開日 2007-09-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Insights into the Mechanism of PEPCK Catalysis Biochemistry, 45, 2006
2RKD	The Structure of rat cytosolic PEPCK in complex with 3-phosphonopropionate 分子名称: 3-PHOSPHONOPROPANOIC ACID, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... 著者 Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. 登録日 2007-10-16 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2RK8	The Structure of rat cytosolic PEPCK in complex with phosphonoformate 分子名称: DI(HYDROXYETHYL)ETHER, FORMIC ACID, MANGANESE (II) ION, ... 著者 Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. 登録日 2007-10-16 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2RKA	The Structure of rat cytosolic PEPCK in complex with phosphoglycolate 分子名称: 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... 著者 Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. 登録日 2007-10-16 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2RKE	The Structure of rat cytosolic PEPCK in complex with sulfoacetate. 分子名称: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... 著者 Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. 登録日 2007-10-16 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2RK7	The Structure of rat cytosolic PEPCK in complex with oxalate 分子名称: MANGANESE (II) ION, OXALATE ION, Phosphoenolpyruvate carboxykinase, ... 著者 Sullivan, S.M, Stiffin, R.M, Carlson, G.M, Holyoak, T. 登録日 2007-10-16 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Differential Inhibition of Cytosolic PEPCK by Substrate Analogues. Kinetic and Structural Characterization of Inhibitor Recognition. Biochemistry, 47, 2008
2ZCI	Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum 分子名称: Phosphoenolpyruvate carboxykinase [GTP] 著者 Aich, S, Prasad, L, Delbaere, L.T.J. 登録日 2007-11-09 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum. Int.J.Biochem.Cell Biol., 40, 2008
3DTB	The structure of rat cytosolic PEPCK in complex with phosphoglycolate and GDP 分子名称: 2-PHOSPHOGLYCOLIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BICARBONATE ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2008-07-14 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT2	The structure of rat cytosolic PEPCK in complex with oxalate and GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2008-07-14 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT7	The structure of rat cytosolic PEPCK in complex with beta-sulfopyruvate and GTP 分子名称: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2008-07-14 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DT4	The structure of rat cytosolic PEPCK in complex with oxalate and GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... 著者 Sullivan, S.M, Holyoak, T. 登録日 2008-07-14 公開日 2008-08-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
3MOE	The structure of rat cytosolic PEPCK mutant A467G in complex with Beta-Sulfopyruvate and GTP 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... 著者 Johnson, T.A, Holyoak, T. 登録日 2010-04-22 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Increasing the conformational entropy of the Omega-loop lid domain in phosphoenolpyruvate carboxykinase impairs catalysis and decreases catalytic fidelity . Biochemistry, 49, 2010

 

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