PDB: 67 resultsInfo pagesStatus searchChemie searchBIRD

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3DT7	The structure of rat cytosolic PEPCK in complex with beta-sulfopyruvate and GTP Descriptor: 2-ETHOXYETHANOL, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2008-07-14 Release date: 2008-08-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enzymes with lid-gated active sites must operate by an induced fit mechanism instead of conformational selection. Proc.Natl.Acad.Sci.Usa, 105, 2008
5I67	Crystal Structure Analysis of MTB PEPCK mutant C273S Descriptor: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Dostal, J, Pachl, P, Machova, I, Pichova, I, Snasel, J. Deposit date: 2016-02-16 Release date: 2016-04-06 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.602 Å) Cite: Crystal Structure Analysis of MTB PEPCK mutant C273S To Be Published
1KHB	PEPCK complex with nonhydrolyzable GTP analog, native data Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.854 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHG	PEPCK Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1KHF	PEPCK complex with PEP Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Dunten, P, Belunis, C, Crowther, R, Hollfelder, K, Kammlott, U, Levin, W, Michel, H, Ramsey, G.B, Swain, A, Weber, D, Wertheimer, S.J. Deposit date: 2001-11-29 Release date: 2002-02-27 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Crystal structure of human cytosolic phosphoenolpyruvate carboxykinase reveals a new GTP-binding site. J.Mol.Biol., 316, 2002
1M51	PEPCK complex with a GTP-competitive inhibitor Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ... Authors: Foley, L.H, Wang, P, Dunten, P, Wertheimer, S.J. Deposit date: 2002-07-06 Release date: 2003-09-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.25 Å) Cite: X-ray Structures of two xanthine inhibitors bound to PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett., 13, 2003
1NHX	PEPCK COMPLEX WITH A GTP-COMPETITIVE INHIBITOR Descriptor: 1,2-ETHANEDIOL, MANGANESE (II) ION, N-{4-[1-(2-FLUOROBENZYL)-3-BUTYL-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YLMETHYL]-PHENYL}-ACETAMIDE, ... Authors: Foley, L.H, Wang, P, Dunten, P, Ramsey, G, Gubler, M.-L, Wertheimer, S.J. Deposit date: 2002-12-19 Release date: 2003-09-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: X-RAY STRUCTURES OF TWO XANTHINE INHIBITORS BOUND TO PEPCK and N-3 modifications of substituted 1,8-Dibenzylxanthines Bioorg.Med.Chem.Lett., 13, 2003
5V9G	Structure of the H477R variant of rat cytosolic PEPCK in complex with oxalate and GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V9H	Structure of the H477R variant of rat cytosolic PEPCK in complex with phosphoglycolate and GDP. Descriptor: 2-PHOSPHOGLYCOLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V95	Structure of the H477R variant of rat cytosolic PEPCK in complex with manganese. Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V9F	Structure of the H477R variant of rat cytosolic PEPCK in complex with beta sulfopyruvate and GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
5V97	Structure of the H477R variant of rat cytosolic PEPCK in complex with GTP. Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Holyoak, T, Cui, D.S. Deposit date: 2017-03-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Asymmetric Anchoring Is Required for Efficient Omega-Loop Opening and Closing in Cytosolic Phosphoenolpyruvate Carboxykinase. Biochemistry, 56, 2017
4GMZ	Structure of rat cytosolic PEPCK Ld_2g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GMM	Structure of rat cytosolic PEPCK Ld_1g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.736 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GMW	Structure of rat cytosolic PEPCK Ld_1g in complex with PEP and GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.75 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GMU	Structure of rat cytosolic PEPCK Ld_1g in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-16 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNQ	Structure of rat cytosolic PEPCK Ld_3g in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNM	Structure of rat cytosolic PEPCK Ld_2g in complex with oxalate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, OXALATE ION, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNP	Structure of rat cytosolic PEPCK Ld_3g in complex with PEP and GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.744 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNO	Structure of rat cytosolic PEPCK Ld_3g in complex with Beta-Sulfopyruvate and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PENTAETHYLENE GLYCOL, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
4GNL	Structure of rat cytosolic PEPCK Ld_2g in complex with PEP and GDP Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Johnson, T.A, Holyoak, T. Deposit date: 2012-08-17 Release date: 2013-07-03 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The {Omega}-loop lid domain of phosphoenolpyruvate carboxykinase is essential for catalytic function. Biochemistry, 51, 2012
2QF2	Rat cytosolic PEPCK in complex with oxaloacetic acid and GDP. Descriptor: GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, OXALOACETATE ION, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2007-06-26 Release date: 2007-08-28 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QF1	Rat cytosolic PEPCK in complex with oxaloacetic acid. Descriptor: MANGANESE (II) ION, OXALOACETATE ION, Phosphoenolpyruvate carboxykinase, ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2007-06-26 Release date: 2007-08-21 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007
2QZY	The structure of chicken mitochondrial PEPCK in complex with PEP Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, ... Authors: Holyoak, T, Sullivan, S.M, Nowak, T. Deposit date: 2007-08-17 Release date: 2007-09-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Insights into the Mechanism of PEPCK Catalysis Biochemistry, 45, 2006
2QEW	Rat cytosolic PEPCK, in complex with manganese ion. Descriptor: MANGANESE (II) ION, Phosphoenolpyruvate carboxykinase, cytosolic [GTP], ... Authors: Sullivan, S.M, Holyoak, T. Deposit date: 2007-06-26 Release date: 2007-08-21 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structures of rat cytosolic PEPCK: insight into the mechanism of phosphorylation and decarboxylation of oxaloacetic acid. Biochemistry, 46, 2007

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