PDB: 367 件ウェブページステータス検索Chemie searchBIRD

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8CBR	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor BDM-2 分子名称: (2S)-2-[3-cyclopropyl-2-(3,4-dihydro-2H-chromen-6-yl)-6-methyl-phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2023-07-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
8CBV	HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT916 分子名称: (2~{S})-2-[3-cyclopropyl-2-(8-fluoranyl-5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)-6-methyl-phenyl]-2-cyclopropyloxy-ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. 登録日 2023-01-25 公開日 2023-06-07 最終更新日 2023-07-26 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase. Antimicrob.Agents Chemother., 67, 2023
2X6N	Human foamy virus integrase - catalytic core. Manganese-bound structure. 分子名称: INTEGRASE, MANGANESE (II) ION 著者 Rety, S, Delelis, O, Rezabkova, L, Dubanchet, B, Silhan, J, Lewit-Bentley, A. 登録日 2010-02-18 公開日 2010-08-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase Acta Crystallogr.,Sect.F, 66, 2010
3KKR	Crystal structure of catalytic core domain of BIV integrase in crystal form I 分子名称: Integrase, NITRATE ION 著者 Shen, Y. 登録日 2009-11-06 公開日 2010-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.453 Å) 主引用文献 Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA Protein Cell, 1, 2010
3KKS	Crystal structure of catalytic core domain of BIV integrase in crystal form II 分子名称: ACETATE ION, GLYCEROL, Integrase 著者 Shen, Y. 登録日 2009-11-06 公開日 2010-09-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA Protein Cell, 1, 2010
3L3V	Structure of HIV-1 integrase core domain in complex with sucrose 分子名称: CADMIUM ION, POL polyprotein, SULFATE ION, ... 著者 Wielens, J, Chalmers, D.K, Scanlon, M.J, Parker, M.W. 登録日 2009-12-18 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site Febs Lett., 584, 2010
3L3U	Crystal structure of the HIV-1 integrase core domain to 1.4A 分子名称: POL polyprotein, SULFATE ION 著者 Wielens, J, Chalmers, D.K, Scanlon, M.J, Parker, M.W. 登録日 2009-12-17 公開日 2010-03-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of the HIV-1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site. Febs Lett., 584, 2010
3LPU	HIV integrase 分子名称: (2S)-2-(6-chloro-2-methyl-4-phenylquinolin-3-yl)pentanoic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ... 著者 Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z. 登録日 2010-02-06 公開日 2010-05-12 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat.Chem.Biol., 6, 2010
3LPT	HIV integrase 分子名称: (6-chloro-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)acetic acid, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, CALCIUM ION, ... 著者 Nicolet, S, Christ, F, Voet, A, Marchand, A, Strelkov, S.V, de Maeyer, M, Chaltin, P, Debyzer, Z. 登録日 2010-02-05 公開日 2010-05-12 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication. Nat.Chem.Biol., 6, 2010
3AO2	Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase 分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-(7-bromo-1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazol-5-amine, ... 著者 Wielens, J, Chalmers, D.K, Headey, S.J, Parker, M.W, Scanlon, M.J. 登録日 2010-09-20 公開日 2011-03-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
3AO1	Fragment-based approach to the design of ligands targeting a novel site in HIV-1 integrase 分子名称: 1,3-benzodioxol-5-ol, CADMIUM ION, POL polyprotein, ... 著者 Wielens, J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. 登録日 2010-09-17 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
3AO5	Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase 分子名称: 5-(7-bromo-1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazol-3-amine, CADMIUM ION, CHLORIDE ION, ... 著者 Wielens, J, Headey, S.J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. 登録日 2010-09-21 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
3AO4	Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase 分子名称: 3-(1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazol-5-amine, CADMIUM ION, CHLORIDE ION, ... 著者 Wielens, J, Headey, S.J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. 登録日 2010-09-20 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
3AO3	Fragment-based approach to the design of ligands targeting a novel site on HIV-1 integrase 分子名称: 3-(1,3-benzodioxol-5-yl)-1-methyl-1H-pyrazole-5-carboxylic acid, CADMIUM ION, CHLORIDE ION, ... 著者 Wielens, J, Headey, S.J, Parker, M.W, Chalmers, D.K, Scanlon, M.J. 登録日 2010-09-20 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Fragment-based design of ligands targeting a novel site on the integrase enzyme of human immunodeficiency virus 1 Chemmedchem, 6, 2011
3AVH	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AV9	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-02 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVF	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVN	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVL	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVA	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-02 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVI	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-02-15 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVB	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-02 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVJ	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVC	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-02 公開日 2012-01-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011
3AVK	Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site 分子名称: ACETIC ACID, CHLORIDE ION, Integrase, ... 著者 Peat, T.S, Deadman, J.J, Newman, J, Rhodes, D.I. 登録日 2011-03-05 公開日 2012-01-18 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures of novel allosteric peptide inhibitors of HIV integrase identify new interactions at the LEDGF binding site. Chembiochem, 12, 2011

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