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6CBP	Crystal structure of the single chain variable fragment of the DH270.6 bnAb in complex with the Man9-V3 glycopeptide Descriptor: DH270.6 single chain variable fragment, Man9-V3 glycopeptide, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, ... Authors: Fera, D, Harrison, S.C. Deposit date: 2018-02-03 Release date: 2018-02-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.17 Å) Cite: HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope. Nat Commun, 9, 2018
8SB4	CryoEM structure of DH270.1-CH848.10.17 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... Authors: Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. Deposit date: 2023-04-02 Release date: 2023-04-19 Last modified: 2023-05-31 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
8SAU	CryoEM structure of DH270.4-CH848.10.17 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848.10.17 gp120, CH848.10.17 gp41, ... Authors: Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. Deposit date: 2023-04-02 Release date: 2023-04-19 Last modified: 2023-05-31 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
8SAZ	CryoEM structure of DH270.I5.6-CH848.10.17 Descriptor: CH848.10.17.SOSIP gp41, DH270.I5.6 variable heavy chain, DH270.I5.6 variable light chain, ... Authors: Henderson, R, Zhou, Y, Stalls, V, Bartesaghi, B, Acharya, P. Deposit date: 2023-04-02 Release date: 2023-04-19 Last modified: 2023-05-31 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nat Commun, 14, 2023
4OM1	Crystal structure of antibody VRC07-I30Q, G54W, S58N in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.131 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLU	Crystal structure of antibody VRC07 in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.202 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLZ	Crystal structure of antibody VRC07-G54W in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLV	Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLY	Crystal structure of antibody VRC07-G54R in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.351 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OM0	Crystal structure of antibody VRC07-G54Y in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.289 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLW	Crystal structure of antibody VRC07-G54H in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.709 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
4OLX	Crystal structure of antibody VRC07-G54L in complex with clade A/E 93TH057 HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen binding fragment of heavy chain: Antibody VRC01, Antigen binding fragment of light chain: Antibody VRC01, ... Authors: Kwon, Y.D, Kwong, P.D. Deposit date: 2014-01-25 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo. J.Virol., 88, 2014
7R74	Crystal structure of llama VHH antibody in complex with HIV-1 HXBC2 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C8 VHH domain, Glycoprotein 120 Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-06-24 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7RI1	Crystal structure of anti-HIV llama VHH antibody J3 in complex with HIV-1 C1086 gp120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Lamma VHH antibody J3, ... Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-07-19 Release date: 2022-03-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7R73	Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, Llama antibody D7 Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-06-24 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.76 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7RI2	Crystal structure of anti-HIV llama VHH antibody A12 in complex with HIV-1 C1086 gp120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, anti-HIV llama VHH antibody A12 Authors: Zhou, T, Kwong, P.D. Deposit date: 2021-07-19 Release date: 2022-03-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure, 30, 2022
7RDW	Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ... Authors: Weidle, C, Pancera, M. Deposit date: 2021-07-12 Release date: 2022-05-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.55 Å) Cite: Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain. Sci Adv, 8, 2022
4R4N	Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... Authors: Acharya, P, Louder, R, Kwong, P.D. Deposit date: 2014-08-19 Release date: 2014-11-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.56 Å) Cite: Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
4RFO	Crystal structure of the ADCC-Potent Antibody N60-I3 Fab in complex with HIV-1 Clade A/E gp120 and M48u1 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade A/E gp120, N60-i3 Fab heavy chain, ... Authors: Tolbert, W.D, Gohain, N, Pazgier, M. Deposit date: 2014-09-26 Release date: 2015-07-15 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
4R4F	Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120 Descriptor: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, ... Authors: Acharya, P, Kwong, P.D. Deposit date: 2014-08-19 Release date: 2014-09-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.514 Å) Cite: Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
4RFN	Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, ... Authors: Gohain, N, Tolbert, W.D, Pazgier, M. Deposit date: 2014-09-26 Release date: 2015-07-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.21 Å) Cite: Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
7SX7	Crystal structure of broadly neutralizing antibody N49P9.3-FR3-3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N49P9.3-FR3-3 ANTIBODY FAB HEAVY CHAIN, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2021-11-22 Release date: 2022-11-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal structure of broadly neutralizing antibody N49P9.3-FR3-3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core To Be Published
7SX6	Crystal structure of broadly neutralizing antibody N49P9.3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, MAGNESIUM ION, ... Authors: Tolbert, W.D, Pazgier, M. Deposit date: 2021-11-22 Release date: 2022-11-30 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Crystal structure of broadly neutralizing antibody N49P9.3 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core To Be Published
7TJP	HIV-1 gp120 complex with CJF-II-195 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, IMIDAZOLE, ... Authors: Gong, Z, Hendrickson, W.A. Deposit date: 2022-01-16 Release date: 2023-01-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.77 Å) Cite: Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines Acs Medicinal Chemistry Letters, 14, 2023
7TJO	HIV-1 gp120 complex with CJF-II-197-S Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, IMIDAZOLE, ... Authors: Gong, Z, Hendrickson, W.A. Deposit date: 2022-01-16 Release date: 2023-01-25 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (3.07 Å) Cite: Structural and Functional Characterization of Indane-Core CD4-Mimetic Compounds Substituted with Heterocyclic Amines ACS Medicinal Chemistry Letters, 14, 2023

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