1PTD
 
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1PTG
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN COMPLEX WITH MYO-INOSITOL | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W, Ryan, M, Bullock, T.L, Griffith, O.H. | | 登録日 | 1995-05-24 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with myo-inositol.
EMBO J., 14, 1995
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1GYM
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C IN COMPLEX WITH GLUCOSAMINE-(ALPHA-1-6)-MYO-INOSITOL | | 分子名称: | (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside, PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W, Ryan, M, Smith, M.P, Weaver, L.H, Keana, J.F.W, Griffith, O.H. | | 登録日 | 1996-05-02 | | 公開日 | 1996-11-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with glucosaminyl(alpha 1-->6)-D-myo-inositol, an essential fragment of GPI anchors.
Biochemistry, 35, 1996
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1QAS
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1QAT
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1DJX
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-1,4,5-TRISPHOSPHATE | | 分子名称: | ACETATE ION, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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1DJZ
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-4,5-BISPHOSPHATE | | 分子名称: | ACETATE ION, CALCIUM ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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1DJW
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHONATE | | 分子名称: | ACETATE ION, CALCIUM ION, INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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1DJY
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2,4,5-TRISPHOSPHATE | | 分子名称: | ACETATE ION, CALCIUM ION, D-MYO-INOSITOL-2,4,5-TRIPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-07 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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1DJG
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH LANTHANUM | | 分子名称: | ACETATE ION, LANTHANUM (III) ION, PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-09-25 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.
Biochemistry, 36, 1997
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1DJH
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH BARIUM | | 分子名称: | ACETATE ION, BARIUM ION, PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-09-25 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.
Biochemistry, 36, 1997
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1DJI
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH CALCIUM | | 分子名称: | ACETATE ION, CALCIUM ION, PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-09-25 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A ternary metal binding site in the C2 domain of phosphoinositide-specific phospholipase C-delta1.
Biochemistry, 36, 1997
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2ISD
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1AOD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C FROM LISTERIA MONOCYTOGENES | | 分子名称: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W, Moser, J. | | 登録日 | 1997-07-02 | | 公開日 | 1998-01-07 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the phosphatidylinositol-specific phospholipase C from the human pathogen Listeria monocytogenes.
J.Mol.Biol., 273, 1997
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2PLC
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2PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D198E | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-16 | | 公開日 | 1998-01-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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3PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D274S | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-17 | | 公開日 | 1998-01-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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7PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT R163K | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-18 | | 公開日 | 1998-01-21 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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5PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT H32A | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-18 | | 公開日 | 1998-01-21 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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6PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT H32L | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-18 | | 公開日 | 1998-01-21 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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4PTD
 | | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D274N | | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | | 著者 | Heinz, D.W. | | 登録日 | 1997-07-18 | | 公開日 | 1998-01-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.
Biochemistry, 36, 1997
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1T6M
 | | X-ray Structure of the R70D PI-PLC enzyme: Insight into the role of calcium and surrounding amino acids on active site geometry and catalysis. | | 分子名称: | 1-phosphatidylinositol phosphodiesterase, CALCIUM ION | | 著者 | Apiyo, D, Zhao, L, Tsai, M.-D, Selby, T.L. | | 登録日 | 2004-05-06 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.107 Å) | | 主引用文献 | X-ray Structure of the R69D Phosphatidylinositol-Specific Phospholipase C Enzyme: Insight into the Role of Calcium and Surrounding Amino Acids in Active Site Geometry and Catalysis.
Biochemistry, 44, 2005
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2FJU
 | | Activated Rac1 bound to its effector phospholipase C beta 2 | | 分子名称: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, CALCIUM ION, ... | | 著者 | Jezyk, M.R, Snyder, J.T, Harden, T.K, Sondek, J. | | 登録日 | 2006-01-03 | | 公開日 | 2006-11-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
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2OR2
 | | Structure of the W47A/W242A Mutant of Bacterial Phosphatidylinositol-Specific Phospholipase C | | 分子名称: | 1-phosphatidylinositol phosphodiesterase | | 著者 | Shao, C, Shi, X, Wehbi, H, Zambonelli, C, Head, J.F, Seaton, B.A, Roberts, M.F. | | 登録日 | 2007-02-01 | | 公開日 | 2007-02-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Dimer structure of an interfacially impaired phosphatidylinositol-specific phospholipase C.
J.Biol.Chem., 282, 2007
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2ZKM
 | | Crystal Structure of Phospholipase C Beta 2 | | 分子名称: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2, CALCIUM ION | | 著者 | Hicks, S.N, Jezyk, M.R, Gershberg, S, Seifert, J.P, Harden, T.K, Sondek, J. | | 登録日 | 2008-03-26 | | 公開日 | 2008-08-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | General and versatile autoinhibition of PLC isozymes
Mol.Cell, 31, 2008
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