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7SJ9
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BU of 7sj9 by Molmil
13pf E254A microtubule from recombinant human tubulin decorated with EB3
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ...
Authors:LaFrance, B.J, Greber, B.J, Zhang, R, McCollum, C, Nogales, E.
Deposit date:2021-10-16
Release date:2022-01-19
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural transitions in the GTP cap visualized by cryo-electron microscopy of catalytically inactive microtubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
4Q58
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BU of 4q58 by Molmil
Crystal structure of the plectin 1a actin-binding domain/integrin beta 4 fragment complex
Descriptor: Integrin beta-4, Plectin
Authors:Song, J.-G, Kostan, J, Grishkovskaya, I, Djinovic-Carugo, K.
Deposit date:2014-04-16
Release date:2014-07-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.001 Å)
Cite:Crystal structure of the plectin 1a actin-binding domain/integrin beta 4 fragment complex
To be Published
6NF1
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BU of 6nf1 by Molmil
Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
Descriptor: (2S)-3-[(3S)-1-(ethylsulfonyl)piperidin-3-yl]-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}propan-1-ol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proto-oncogene vav, ...
Authors:Knapp, M.S, Elling, R.A, Ornelas, E.
Deposit date:2018-12-18
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity
To Be Published
6M5G
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BU of 6m5g by Molmil
F-actin-Utrophin complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Kumari, A, Ragunath, V.K, Sirajuddin, M.
Deposit date:2020-03-10
Release date:2020-05-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into actin filament recognition by commonly used cellular actin markers.
Embo J., 39, 2020
3F7P
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BU of 3f7p by Molmil
Crystal structure of a complex between integrin beta4 and plectin
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:de Pereda, J.M.
Deposit date:2008-11-10
Release date:2009-03-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes
Embo J., 28, 2009
7SQC
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BU of 7sqc by Molmil
Ciliary C1 central pair apparatus isolated from Chlamydomonas reinhardtii
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CPC1, Calmodulin, ...
Authors:Gui, M, Wang, X, Dutcher, S.K, Brown, A, Zhang, R.
Deposit date:2021-11-05
Release date:2022-04-13
Last modified:2022-06-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
Nat.Struct.Mol.Biol., 29, 2022
7SXA
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BU of 7sxa by Molmil
T-Plastin-F-actin complex, pre-bundling intermediate state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Reynolds, M.J, Alushin, G.M.
Deposit date:2021-11-22
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (6.87 Å)
Cite:Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SX8
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BU of 7sx8 by Molmil
T-Plastin-F-actin complex, parallel bundled state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Reynolds, M.J, Alushin, G.M.
Deposit date:2021-11-22
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SX9
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BU of 7sx9 by Molmil
T-Plastin-F-actin complex, anti-parallel bundled state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Mei, L, Reynolds, M.J, Alushin, G.M.
Deposit date:2021-11-22
Release date:2022-08-31
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
3JAR
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BU of 3jar by Molmil
Cryo-EM structure of GDP-microtubule co-polymerized with EB3
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, R, Nogales, E.
Deposit date:2015-06-19
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAL
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BU of 3jal by Molmil
Cryo-EM structure of GMPCPP-microtubule co-polymerized with EB3
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Microtubule-associated protein RP/EB family member 3, ...
Authors:Zhang, R, Nogales, E.
Deposit date:2015-06-16
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3JAK
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BU of 3jak by Molmil
Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound)
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, R, Nogales, E.
Deposit date:2015-06-16
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
3KY9
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BU of 3ky9 by Molmil
Autoinhibited Vav1
Descriptor: Proto-oncogene vav, ZINC ION
Authors:Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B.
Deposit date:2009-12-04
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.731 Å)
Cite:Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010

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數據於2024-04-24公開中

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