PDB: 121 件ウェブページステータス検索Chemie searchBIRD

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5V2M	Mevalonate diphosphate mediated ATP binding mechanism of the mevalonate diphosphate decarboxylase from Enterococcus faecalis 分子名称: Mevalonate diphosphate decarboxylase, SULFATE ION 著者 Stauffacher, C.V, Chen, C.-L. 登録日 2017-03-05 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.989 Å) 主引用文献 Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis. J. Biol. Chem., 292, 2017
3GON	Streptococcus pneumoniae Phosphomevalonate Kinase in Complex with Phosphomevalonate and AMPPNP 分子名称: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Andreassi, J.L, Bilder, P.W, Vetting, M.W, Roderick, S.L, Leyh, T.S. 登録日 2009-03-19 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the ternary complex of phosphomevalonate kinase: the enzyme and its family Biochemistry, 48, 2009
5WAT	Corynebacterium glutamicum Full length Homoserine kinase 分子名称: HEXAETHYLENE GLYCOL, Homoserine kinase, MAGNESIUM ION, ... 著者 Petit, C, Ronning, D.R. 登録日 2017-06-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.141 Å) 主引用文献 Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis. ACS Omega, 3, 2018
5WAS	Corynebacterium glutamicum Hydrolyzed Homoserine kinase 分子名称: Homoserine kinase, PHOSPHATE ION 著者 Petit, C, Ronning, D.R. 登録日 2017-06-27 公開日 2018-02-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Reduction of Feedback Inhibition in Homoserine Kinase (ThrB) ofCorynebacterium glutamicumEnhances l-Threonine Biosynthesis. ACS Omega, 3, 2018
1OJ4	Ternary complex of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 分子名称: 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL, 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLORIDE ION, ... 著者 Miallau, L, Alphey, M.S, Hunter, W.N. 登録日 2003-06-30 公開日 2003-07-31 最終更新日 2019-10-16 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase Proc.Natl.Acad.Sci.USA, 100, 2003
3HUL	Structure of putative homoserine kinase thrB from Listeria monocytogenes 分子名称: Homoserine kinase, SULFATE ION 著者 Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-06-15 公開日 2009-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure of putative homoserine kinase thrB from Listeria monocytogenes To be published
1VIS	Crystal structure of mevalonate kinase 分子名称: 1,4-DIETHYLENE DIOXIDE, Mevalonate kinase 著者 Structural GenomiX 登録日 2003-12-01 公開日 2003-12-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
1WUU	crystal structure of human galactokinase complexed with MgAMPPNP and galactose 分子名称: Galactokinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Thoden, J.B, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2004-12-08 公開日 2004-12-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular Structure of Human Galactokinase: IMPLICATIONS FOR TYPE II GALACTOSEMIA J.Biol.Chem., 280, 2005
2A2C	x-ray structure of human N-acetyl galactosamine kinase complexed with Mg-ADP and N-acetyl galactosamine 1-phosphate 分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-galactopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
2A2D	X-ray structure of human n-acetyl galactosamine kinase complexed with Mn-AMPPNP and n-acetyl glactosamine 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, MANGANESE (II) ION, N-acetylgalactosamine kinase, ... 著者 Thoden, J.B, Holden, H.M. 登録日 2005-06-22 公開日 2005-07-05 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The molecular architecture of human N-acetylgalactosamine kinase. J.Biol.Chem., 280, 2005
2AJ4	Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP 分子名称: CHLORIDE ION, Galactokinase, MAGNESIUM ION, ... 著者 Thoden, J.B, Sellick, C.A, Timson, D.J, Reece, R.J, Holden, H.M. 登録日 2005-08-01 公開日 2005-08-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer J.Biol.Chem., 280, 2005
1FI4	THE X-RAY CRYSTAL STRUCTURE OF MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE AT 2.3 ANGSTROM RESOLUTION. 分子名称: MEVALONATE 5-DIPHOSPHATE DECARBOXYLASE 著者 Bonanno, J.B, Edo, C, Eswar, N, Pieper, U, Romanowski, M.J, Ilyin, V, Gerchman, S.E, Kycia, H, Studier, F.W, Sali, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2000-08-03 公開日 2001-03-21 最終更新日 2021-02-03 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis. Proc.Natl.Acad.Sci.USA, 98, 2001
6Q8Z	Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-16 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide To Be Published
6Q91	Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 5-chloranyl-2-methoxy-~{N}-(2-methylpropyl)benzamide, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-17 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide To Be Published
1FWK	CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, HOMOSERINE KINASE, MAGNESIUM ION 著者 Zhou, T, Daugherty, M, Grishin, N.V, Osterman, A.L, Zhang, H. 登録日 2000-09-22 公開日 2000-12-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily. Structure Fold.Des., 8, 2000
6Q3W	Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-04 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.962 Å) 主引用文献 Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate To Be Published
6Q3X	Structure of human galactokinase in complex with galactose and 2'-(benzo[d]oxazol-2-ylamino)-7',8'-dihydro-1'H-spiro[cyclohexane-1,4'-quinazolin]-5'(6'H)-one 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, ... 著者 Bezerra, G.A, Mackinnon, S, Zhang, M, Foster, W, Bailey, H, Arrowsmith, C, Edwards, A, Bountra, C, Lai, K, Yue, W.W, Structural Genomics Consortium (SGC) 登録日 2018-12-04 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia. Acs Chem.Biol., 16, 2021
1FWL	CRYSTAL STRUCTURE OF HOMOSERINE KINASE 分子名称: HOMOSERINE KINASE 著者 Zhou, T, Daugherty, M, Grishin, N.V, Osterman, A.L, Zhang, H. 登録日 2000-09-22 公開日 2000-12-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily. Structure Fold.Des., 8, 2000
6XR5	Crystal Structure of Diphosphomevalonate decarboxylase (MVD1) Cryptococcus neoformans var. grubii serotype A 分子名称: 1,2-ETHANEDIOL, ADENINE, Diphosphomevalonate decarboxylase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-07-11 公開日 2020-09-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Diphosphomevalonate decarboxylase (MVD1) from Cryptococcus neoformans var. grubii serotype A to be published
6QJE	Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 4-[(2-methylsulfonylimidazol-1-yl)methyl]-1,3-thiazole, Galactokinase, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2019-01-24 公開日 2019-02-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole To Be Published
6Q90	Structure of human galactokinase 1 bound with 1-(4-Methoxyphenyl)-3-(4-pyridinyl)urea 分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, N-(4-methoxyphenyl)-N'-pyridin-4-ylurea, ... 著者 Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W. 登録日 2018-12-16 公開日 2019-01-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of human galactokinase 1 bound with 1-(4-Methoxyphenyl)-3-(4-pyridinyl)urea To Be Published
6MDE	Mevalonate kinase from Methanosarcina mazei with mevalonate bound 分子名称: (R)-MEVALONATE, GLYCEROL, Mevalonate kinase, ... 著者 Miller, B.R, Kung, Y. 登録日 2018-09-04 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insight into substrate and product binding in an archaeal mevalonate kinase. PLoS ONE, 13, 2018
6MDF	Mevalonate kinase from Methanosarcina mazei with 5-phosphomevalonate bound 分子名称: (3R)-3-HYDROXY-3-METHYL-5-(PHOSPHONOOXY)PENTANOIC ACID, GLYCEROL, Mevalonate kinase 著者 Miller, B.R, Kung, Y. 登録日 2018-09-04 公開日 2018-12-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structural insight into substrate and product binding in an archaeal mevalonate kinase. PLoS ONE, 13, 2018
6N10	Crystal structure of Arabidopsis thaliana mevalonate 5-diphosphate decarboxylase 1 complexed with (R)-MVAPP 分子名称: (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID, Diphosphomevalonate decarboxylase MVD1, peroxisomal, ... 著者 Noel, J.P, Thomas, S.T, Louie, G.V. 登録日 2018-11-07 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase. Acs Chem.Biol., 14, 2019
1H72	CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH HSE 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HOMOSERINE KINASE, L-HOMOSERINE, ... 著者 Krishna, S.S, Zhou, T, Daugherty, M, Osterman, A.L, Zhang, H. 登録日 2001-07-02 公開日 2001-09-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for the Catalysis and Substrate Specificity of Homoserine Kinase Biochemistry, 40, 2001

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