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3MK2
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Placental alkaline phosphatase complexed with Phe
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Alkaline phosphatase, ...
Authors:Stec, B, Cheltsov, A, Millan, J.L.
Deposit date:2010-04-13
Release date:2011-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Acta Crystallogr.,Sect.F, 66, 2010
3MK1
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Refinement of placental alkaline phosphatase complexed with nitrophenyl
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Alkaline phosphatase, ...
Authors:Stec, B, Cheltsov, A, Millan, J.L.
Deposit date:2010-04-13
Release date:2011-01-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Acta Crystallogr.,Sect.F, 66, 2010
2X98
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BU of 2x98 by Molmil
H.SALINARUM ALKALINE PHOSPHATASE
Descriptor: ALKALINE PHOSPHATASE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Wende, A, Johansson, P, Grininger, M, Oesterhelt, D.
Deposit date:2010-03-14
Release date:2010-05-19
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Biochemical Characterization of a Halophilic Archaeal Alkaline Phosphatase.
J.Mol.Biol., 400, 2010
3A52
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Crystal structure of cold-active alkailne phosphatase from psychrophile Shewanella sp.
Descriptor: Cold-active alkaline phosphatase, MAGNESIUM ION, SULFATE ION, ...
Authors:Tsuruta, H, Mikami, B, Higashi, T, Aizono, Y.
Deposit date:2009-07-24
Release date:2010-04-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of cold-active alkaline phosphatase from the psychrophile Shewanella sp.
Biosci.Biotechnol.Biochem., 74, 2010
2W5X
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BU of 2w5x by Molmil
Structure of TAB5 alkaline phosphatase mutant His 135 Glu with Mg bound in the M3 site.
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, ZINC ION
Authors:Koutsioulis, D, Lyskowski, A, Maki, S, Guthrie, E, Feller, G, Bouriotis, V, Heikinheimo, P.
Deposit date:2008-12-15
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
Protein Sci., 19, 2010
2W5V
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Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Mg bound in the M3 site.
Descriptor: ALKALINE PHOSPHATASE, MAGNESIUM ION, ZINC ION
Authors:Koutsioulis, D, Lyskowski, A, Maki, S, Guthrie, E, Feller, G, Bouriotis, V, Heikinheimo, P.
Deposit date:2008-12-15
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
Protein Sci., 19, 2010
2W5W
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Structure of TAB5 alkaline phosphatase mutant His 135 Asp with Zn bound in the M3 site.
Descriptor: ALKALINE PHOSPHATASE, ZINC ION
Authors:Koutsioulis, D, Lyskowski, A, Maki, S, Guthrie, E, Feller, G, Bouriotis, V, Heikinheimo, P.
Deposit date:2008-12-15
Release date:2009-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Coordination Sphere of the Third Metal Site is Essential to the Activity and Metal Selectivity of Alkaline Phosphatases.
Protein Sci., 19, 2010
3E2D
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The 1.4 A crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase
Descriptor: 1,2-ETHANEDIOL, Alkaline phosphatase, MAGNESIUM ION, ...
Authors:Helland, R, Larsen, R.L, Asgeirsson, B.
Deposit date:2008-08-05
Release date:2009-06-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The 1.4 A crystal structure of the large and cold-active Vibrio sp. alkaline phosphatase.
Biochim.Biophys.Acta, 1794, 2009
3DYC
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Structure of E322Y Alkaline Phosphatase in Complex with Inorganic Phosphate
Descriptor: Alkaline phosphatase, PHOSPHATE ION, ZINC ION
Authors:Zalatan, J.G, Fenn, T.D, Herschlag, D.
Deposit date:2008-07-25
Release date:2008-10-21
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion.
J.Mol.Biol., 384, 2008
3DPC
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Structure of E.coli Alkaline Phosphatase Mutant in Complex with a Phosphorylated Peptide
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkaline phosphatase, PHOSPHATE ION, ...
Authors:Wang, W.H, Jiang, T.
Deposit date:2008-07-07
Release date:2009-06-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Development of a universal phosphorylated peptide-binding protein for simultaneous assay of kinases
Biosens.Bioelectron., 24, 2009
3CMR
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E. coli alkaline phosphatase mutant R166S in complex with phosphate
Descriptor: Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:O'Brien, P.J, Lassila, J.K, Fenn, T.D, Zalatan, J.G, Herschlag, D.
Deposit date:2008-03-24
Release date:2008-07-29
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Arginine coordination in enzymatic phosphoryl transfer: evaluation of the effect of Arg166 mutations in Escherichia coli alkaline phosphatase
Biochemistry, 47, 2008
3BDF
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Crystal structure of metal-free E. coli alkaline phosphatase (T155V)
Descriptor: Alkaline phosphatase, SULFATE ION
Authors:Grigg, J.C, Murphy, M.E.
Deposit date:2007-11-14
Release date:2008-11-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Active-Site Trimetallic Cluster of Alkaline Phosphatase is Lost Upon Isosteric Mutation at the Mg2+-Coordinating Residue Threonine-155
To be Published
3BDG
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Crystal structure of wild-type/T155V mixed dimer of E. coli alkaline phosphatase
Descriptor: Alkaline phosphatase, SULFATE ION
Authors:Grigg, J.C, Murphy, M.E.
Deposit date:2007-11-14
Release date:2008-11-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Active-Site Trimetallic Cluster of Alkaline Phosphatase is Lost Upon Isosteric Mutation at the Mg2+-Coordinating Residue Threonine-155
To be Published
3BDH
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Crystal structure of zinc-deficient wild-type E. coli alkaline phosphatase
Descriptor: Alkaline phosphatase, MAGNESIUM ION
Authors:Grigg, J.C, Murphy, M.E.
Deposit date:2007-11-14
Release date:2008-11-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Active-Site Trimetallic Cluster of Alkaline Phosphatase is Lost Upon Isosteric Mutation at the Mg2+-Coordinating Residue Threonine-155
To be Published
2IUC
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BU of 2iuc by Molmil
Structure of alkaline phosphatase from the Antarctic bacterium TAB5
Descriptor: ALKALINE PHOSPHATASE, CACODYLATE ION, MAGNESIUM ION, ...
Authors:Wang, E, Koutsioulis, D, Leiros, H.K.S, Andersen, O.A, Bouriotis, V, Hough, E, Heikinheimo, P.
Deposit date:2006-06-01
Release date:2006-11-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Alkaline Phosphatase from the Antarctic Bacterium Tab5.
J.Mol.Biol., 366, 2007
2GLQ
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X-ray structure of human alkaline phosphatase in complex with strontium
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, placental type, ...
Authors:Llinas, P, Masella, M, Stigbrand, T, Menez, A, Stura, E.A, Le Du, M.H.
Deposit date:2006-04-05
Release date:2006-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural studies of human alkaline phosphatase in complex with strontium: Implication for its secondary effect in bones.
Protein Sci., 15, 2006
2G9Y
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Structure of S102T E. coli alkaline phosphatase in presence of phosphate at 2.00 A resolution
Descriptor: Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Wang, J, Kantrowitz, E.R.
Deposit date:2006-03-07
Release date:2006-10-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine.
Protein Sci., 15, 2006
2GA3
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BU of 2ga3 by Molmil
Structure of S102T E. coli Alkaline Phosphatase-phosphate intermediate at 2.20A resolution
Descriptor: Alkaline phosphatase, MAGNESIUM ION, SULFATE ION, ...
Authors:Wang, J, Kantrowitz, E.R.
Deposit date:2006-03-07
Release date:2006-10-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine.
Protein Sci., 15, 2006
1ZEF
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BU of 1zef by Molmil
structure of alkaline phosphatase from human placenta in complex with its uncompetitive inhibitor L-Phe
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, CALCIUM ION, ...
Authors:Llinas, P, Stura, E.A, Menez, A, Kiss, Z, Stigbrand, T, Millan, J.L, Le Du, M.H.
Deposit date:2005-04-18
Release date:2005-06-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
J.Mol.Biol., 350, 2005
1ZEB
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BU of 1zeb by Molmil
X-ray structure of alkaline phosphatase from human placenta in complex with 5'-AMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, CALCIUM ION, ...
Authors:Llinas, P, Stura, E.A, Menez, A, Kiss, Z, Stigbrand, T, Millan, J.L, Le Du, M.H.
Deposit date:2005-04-18
Release date:2005-06-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
J.Mol.Biol., 350, 2005
1ZED
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BU of 1zed by Molmil
Alkaline phosphatase from human placenta in complex with p-nitrophenyl-phosphonate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, CALCIUM ION, ...
Authors:Llinas, P, Stura, E.A, Menez, A, Kiss, Z, Stigbrand, T, Millan, J.L, Le Du, M.H.
Deposit date:2005-04-18
Release date:2005-06-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural Studies of Human Placental Alkaline Phosphatase in Complex with Functional Ligands.
J.Mol.Biol., 350, 2005
1Y7A
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Structure of D153H/K328W E. coli alkaline phosphatase in presence of cobalt at 1.77 A resolution
Descriptor: Alkaline phosphatase, COBALT (II) ION, PHOSPHATE ION, ...
Authors:Wang, J, Stieglitz, K, Kantrowitz, E.R.
Deposit date:2004-12-08
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Metal Specificity Is Correlated with Two Crucial Active Site Residues in Escherichia coli Alkaline Phosphatase(,).
Biochemistry, 44, 2005
1Y6V
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Structure of E. coli Alkaline Phosphatase in presence of cobalt at 1.60 A resolution
Descriptor: Alkaline phosphatase, COBALT (II) ION, PHOSPHATE ION, ...
Authors:Wang, J, Stieglitz, K, Kantrowitz, E.R.
Deposit date:2004-12-07
Release date:2005-06-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Metal Specificity Is Correlated with Two Crucial Active Site Residues in Escherichia coli Alkaline Phosphatase(,).
Biochemistry, 44, 2005
1SHQ
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Crystal structure of shrimp alkaline phosphatase with magnesium in M3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, SULFATE ION, ...
Authors:de Backer, M.M.E, McSweeney, S, Lindley, P.F, Hough, E.
Deposit date:2004-02-26
Release date:2004-08-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
Acta Crystallogr.,Sect.D, 60, 2004
1SHN
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Crystal structure of shrimp alkaline phosphatase with phosphate bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, SULFATE ION, ...
Authors:de Backer, M.M.E, McSweeney, S, Lindley, P.F, Hough, E.
Deposit date:2004-02-26
Release date:2004-08-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ligand-binding and metal-exchange crystallographic studies on shrimp alkaline phosphatase.
Acta Crystallogr.,Sect.D, 60, 2004

219515

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