PDB: 1333 件ウェブページステータス検索Chemie searchBIRD

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1CNK	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE 分子名称: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1995-04-03 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNG	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE 分子名称: CARBONIC ANHYDRASE II, CHLORIDE ION, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1995-04-03 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNH	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE 分子名称: CARBONIC ANHYDRASE II, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1995-04-03 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNI	X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1995-04-03 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site J.Am.Chem.Soc., 117, 1995
1CNX	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS 分子名称: AMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Boriack, P.A, Christianson, D.W. 登録日 1995-07-21 公開日 1995-11-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNW	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS 分子名称: AMINOMETHYLENECARBONYLAMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Boriack, P.A, Christianson, D.W. 登録日 1995-07-21 公開日 1995-11-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1CNY	SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE, ... 著者 Boriack, P.A, Christianson, D.W. 登録日 1995-07-21 公開日 1995-11-14 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants. J.Med.Chem., 38, 1995
1DMX	MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AT 2.45 ANGSTROMS RESOLUTION 分子名称: MURINE CARBONIC ANHYDRASE V, ZINC ION 著者 Boriack-Sjodin, P.A, Christianson, D.W. 登録日 1995-10-04 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design. Proc.Natl.Acad.Sci.USA, 92, 1995
1DMY	COMPLEX BETWEEN MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AND THE TRANSITION STATE ANALOGUE ACETAZOLAMIDE 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, MURINE CARBONIC ANHYDRASE V, ZINC ION 著者 Boriack-Sjodin, P.A, Christianson, D.W. 登録日 1995-10-04 公開日 1996-04-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design. Proc.Natl.Acad.Sci.USA, 92, 1995
1ZSC	CARBONIC ANHYDRASE II MUTANT E117Q, HOLO FORM 分子名称: CARBONIC ANHYDRASE II, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1996-01-09 公開日 1996-07-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry, 35, 1996
1ZSB	CARBONIC ANHYDRASE II MUTANT E117Q, TRANSITION STATE ANALOGUE ACETAZOLAMIDE 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, CARBONIC ANHYDRASE II, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1996-01-09 公開日 1996-07-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry, 35, 1996
1ZSA	CARBONIC ANHYDRASE II MUTANT E117Q, APO FORM 分子名称: CARBONIC ANHYDRASE II 著者 Lesburg, C.A, Christianson, D.W. 登録日 1996-01-09 公開日 1996-07-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II. Biochemistry, 35, 1996
1OKM	CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE 分子名称: 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. 登録日 1996-06-25 公開日 1997-01-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118, 1996
1OKN	CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKN INHIBITOR 4-SULFONAMIDE-[1-(4-N-(5-FLUORESCEIN THIOUREA)BUTANE)] 分子名称: 4-SULFONAMIDE-[4-(THIOMETHYLAMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W. 登録日 1996-06-25 公開日 1997-01-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118, 1996
1OKL	CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKL INHIBITOR 5-DIMETHYLAMINO-NAPHTHALENE-1-SULFONAMIDE 分子名称: 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Nair, S.K, Elbaum, D, Christianson, D.W. 登録日 1996-06-25 公開日 1997-01-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Unexpected binding mode of the sulfonamide fluorophore 5-dimethylamino-1-naphthalene sulfonamide to human carbonic anhydrase II. Implications for the development of a zinc biosensor. J.Biol.Chem., 271, 1996
1URT	MURINE CARBONIC ANHYDRASE V 分子名称: CARBONIC ANHYDRASE V, ZINC ION 著者 Boriack-Sjodin, P.A, Christianson, D.W. 登録日 1996-07-03 公開日 1997-01-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-based design of an intramolecular proton transfer site in murine carbonic anhydrase V. Biochemistry, 35, 1996
1UGE	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY LEU (A65L) 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGD	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S) 分子名称: CARBONIC ANHYDRASE II, ZINC ION 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGB	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY GLY (A65G) 分子名称: AZIDE ION, CARBONIC ANHYDRASE II, ZINC ION 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGG	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY SER (A65S)-ORTHORHOMBIC FORM 分子名称: CARBONIC ANHYDRASE II, ZINC ION 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGF	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T) 分子名称: AZIDE ION, CARBONIC ANHYDRASE II, MERCURY (II) ION, ... 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGA	HUMAN CARBONIC ANHYDRASE II[HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY PHE (A65F) 分子名称: CARBONIC ANHYDRASE II, ZINC ION 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1UGC	HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY HIS (A65H) 分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION 著者 Scolnick, L.R, Christianson, D.W. 登録日 1996-07-24 公開日 1997-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic studies of alanine-65 variants of carbonic anhydrase II reveal the structural basis of compromised proton transfer in catalysis. Biochemistry, 35, 1996
1ZNC	HUMAN CARBONIC ANHYDRASE IV 分子名称: CARBONIC ANHYDRASE IV, SULFATE ION, ZINC ION 著者 Stams, T, Christianson, D.W. 登録日 1996-09-17 公開日 1997-09-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-A resolution. Proc.Natl.Acad.Sci.USA, 93, 1996
1H4N	H94N CARBONIC ANHYDRASE II COMPLEXED WITH TRIS 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONIC ANHYDRASE II, ZINC ION 著者 Lesburg, C.A, Christianson, D.W. 登録日 1997-05-29 公開日 1997-09-17 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity. Biochemistry, 36, 1997

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