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4EU1
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Structure of a mitochondrial aspartate aminotransferase from Trypanosoma brucei
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Mitochondrial aspartate aminotransferase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-04-25
Release date:2012-05-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.
Acta Crystallogr F Struct Biol Commun, 71, 2015
5VER
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BU of 5ver by Molmil
MOUSE KYNURENINE AMINOTRANSFERASE III, RE-REFINEMENT OF THE PDB STRUCTURE 3E2Z
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
Deposit date:2017-04-05
Release date:2017-11-29
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
6HND
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BU of 6hnd by Molmil
Crystal structure of the aromatic aminotransferase Aro9 from C. Albicans
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Aromatic-amino-acid:2-oxoglutarate transaminase, POTASSIUM ION, ...
Authors:Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I.
Deposit date:2018-09-14
Release date:2019-02-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
2QB3
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BU of 2qb3 by Molmil
Structural Studies Reveal the Inactivation of E. coli L-Aspartate Aminotransferase by (s)-4,5-dihydro-2-thiophenecarboxylic acid (SADTA) via Two Mechanisms (at pH 7.5)
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ...
Authors:Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D.
Deposit date:2007-06-15
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
6HNV
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Crystal structure of aminotransferase Aro9 from C. Albicans with ligands
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINOHEXANEDIOIC ACID, 2-OXOADIPIC ACID, ...
Authors:Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I.
Deposit date:2018-09-17
Release date:2019-02-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
6HNB
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Crystal structure of aminotransferase Aro8 from Candida albicans
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Aromatic amino acid aminotransferase I, CHLORIDE ION, ...
Authors:Kiliszek, A, Rzad, K, Rypniewski, W, Milewski, S, Gabriel, I.
Deposit date:2018-09-14
Release date:2019-02-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structures of aminotransferases Aro8 and Aro9 from Candida albicans and structural insights into their properties.
J.Struct.Biol., 205, 2019
5VJZ
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Joint X-ray/neutron structure of aspartate aminotransferase with alpha-methyl-aspartate at pH 7.5
Descriptor: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, Aspartate aminotransferase, cytoplasmic
Authors:Dajnowicz, S, Kovalevsky, A.Y, Mueser, T.C.
Deposit date:2017-04-20
Release date:2017-11-01
Last modified:2022-03-16
Method:NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION
Cite:Direct visualization of critical hydrogen atoms in a pyridoxal 5'-phosphate enzyme.
Nat Commun, 8, 2017
2QBT
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Structural Studies Reveal The Inactivation of E. coli L-aspartate aminotransferase by (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via Two Mechanisms (at pH 8.0)
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ...
Authors:Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D.
Deposit date:2007-06-18
Release date:2007-09-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inactivation of Escherichia coli l-Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid Reveals "A Tale of Two Mechanisms".
Biochemistry, 46, 2007
5VEP
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BU of 5vep by Molmil
MOUSE KYNURENINE AMINOTRANSFERASE III, RE-REFINEMENT OF THE PDB STRUCTURE 3E2F
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
Deposit date:2017-04-05
Release date:2017-11-29
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
4F5J
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BU of 4f5j by Molmil
Rational Design and Directed Evolution for Conversion of Substrate Specificity from E.coli Aspartate Aminotransferase to Tyrosine Aminotransferase: Mutant P5.
Descriptor: Aspartate aminotransferase
Authors:Addington, T.A, Fisher, A.J, Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5F
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BU of 4f5f by Molmil
Structure of Aspartate Aminotransferase Conversion to Tyrosine Aminotransferase: Chimera P1.
Descriptor: Aspartate aminotransferase
Authors:Addington, T.A, Fisher, A.J, Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
2QA3
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BU of 2qa3 by Molmil
Structural Studies Reveal the Inactivation of E. coli L-aspartate aminotransferase by (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via two mechanisms (at pH6.5)
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ...
Authors:Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D.
Deposit date:2007-06-14
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
4F5M
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BU of 4f5m by Molmil
Wild-Type E. coli Aspartate Aminotransferase: A Template For The Interconversion of Substrate Specificity and Activity To Tyrosine Aminotransferase By The JANUS Algorithm.
Descriptor: 1,2-ETHANEDIOL, Aspartate aminotransferase
Authors:Addington, T.A, Fisher, A.J, Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5I
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BU of 4f5i by Molmil
Substrate Specificity Conversion of E. coli Pyridoxal-5'-Phosphate Dependent Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P4.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Aspartate aminotransferase
Authors:Addington, T.A, Fisher, A.J, Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
4F5H
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BU of 4f5h by Molmil
Intercoversion of Substrate Specificity: E. coli Aspatate Aminotransferase to Tyrosine Aminotransferase: Chimera P3.
Descriptor: Aspartate aminotransferase
Authors:Addington, T.A, Fisher, A.J, Toney, M.D.
Deposit date:2012-05-13
Release date:2013-02-13
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Janus: prediction and ranking of mutations required for functional interconversion of enzymes.
J.Mol.Biol., 425, 2013
6L1L
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BU of 6l1l by Molmil
Apo-BacF structure from Bacillus subtillis
Descriptor: Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Balasubramanian, G, Deshmukh, A.A.
Deposit date:2019-09-29
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6L1N
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Substrate bound BacF structure from Bacillus subtillis
Descriptor: Aminotransferase, GLYCINE, PYRIDOXAL-5'-PHOSPHATE
Authors:Balasubramanian, G, Deshmukh, A.A.
Deposit date:2019-09-29
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6EZL
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BU of 6ezl by Molmil
Crystal structure of aspartate aminotransferase from Trypanosoma cruzi at 2.07 Angstrom resolution
Descriptor: Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Jagoe, W.N, Khan, A.R.
Deposit date:2017-11-15
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure of aspartate aminotransferase from Trypanosoma Cruzi at 2.07 Angstrom resolution
To Be Published
6F35
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BU of 6f35 by Molmil
Crystal structure of the aspartate aminotranferase from Rhizobium meliloti
Descriptor: ACETATE ION, Aspartate aminotransferase B, GLYCEROL, ...
Authors:Cobessi, D, Graindorge, M, Giustini, C, Matringe, M.
Deposit date:2017-11-28
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase.
Febs J., 286, 2019
6F5V
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BU of 6f5v by Molmil
Crystal structure of the prephenate aminotransferase from Arabidopsis thaliana
Descriptor: Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, CITRIC ACID, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Cobessi, D, Robin, A, Giustini, C, Graindorge, M, Matringe, M.
Deposit date:2017-12-03
Release date:2019-03-13
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase.
Febs J., 286, 2019
6L1O
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BU of 6l1o by Molmil
Product bound BacF structure from Bacillus subtillis
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Balasubramanian, G, Deshmukh, A.A.
Deposit date:2019-09-29
Release date:2020-03-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6LIG
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BU of 6lig by Molmil
Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) in complex with AH
Descriptor: 3-[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]-5-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methylidene]-4-oxidanyl-furan-2-one, Glutamate oxaloacetate transaminase 1, PYRIDOXAL-5'-PHOSPHATE
Authors:Yan, S, Sun, W.G, Zhang, Y.H.
Deposit date:2019-12-10
Release date:2020-12-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) in complex with AH
To Be Published
6F77
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BU of 6f77 by Molmil
Crystal structure of the prephenate aminotransferase from Rhizobium meliloti
Descriptor: Aspartate aminotransferase A, PYRIDOXAL-5'-PHOSPHATE
Authors:Cobessi, D, Giustini, C, Graindorge, M, Matringe, M.
Deposit date:2017-12-07
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase.
Febs J., 286, 2019
4R8D
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BU of 4r8d by Molmil
Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Histidinol-phosphate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Nasir, N, Anant, A, Vyas, R, Biswal, B.K.
Deposit date:2014-09-01
Release date:2015-09-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis
To be Published
4R5Z
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BU of 4r5z by Molmil
Crystal structure of Rv3772 encoded aminotransferase
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Nasir, N, Anant, A, Vyas, R, Biswal, B.K.
Deposit date:2014-08-22
Release date:2015-08-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities
Sci Rep, 6, 2016

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