2JHI
 
 | | Structure of globular heads of M-ficolin complexed with N-acetyl-D- galactosamine | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, FICOLIN-1 | | Authors: | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | | Deposit date: | 2007-02-22 | | Release date: | 2007-10-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch.
J.Biol.Chem., 282, 2007
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6ZQX
 | | Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with N,N'-diacetyl chitobiose ligand bound | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ... | | Authors: | Shrive, A.K, Greenhough, T.J, Williams, H.M. | | Deposit date: | 2020-07-10 | | Release date: | 2021-07-21 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Crystal structures of human immune protein FIBCD1 suggest an extended binding site compatible with recognition of pathogen associated carbohydrate motifs
J.Biol.Chem., 2023
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6ZQY
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8FN8
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2D39
 | | Trivalent Recognition Unit of Innate Immunity System; Crystal Structure of human M-ficolin Fibrinogen-like Domain | | Descriptor: | CALCIUM ION, Ficolin-1 | | Authors: | Tanio, M, Kondo, S, Sugio, S, Kohno, T. | | Deposit date: | 2005-09-26 | | Release date: | 2006-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Trivalent recognition unit of innate immunity system; crystal structure of trimeric human m-ficolin fibrinogen-like domain
J.Biol.Chem., 282, 2007
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4JZC
 | | Angiopoietin-2 fibrinogen domain TAG mutant | | Descriptor: | Angiopoietin-2 | | Authors: | Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A. | | Deposit date: | 2013-04-02 | | Release date: | 2013-05-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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6ZQR
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6ZR0
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2J1G
 | | L-ficolin complexed to N-acetyl-cystein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | | Authors: | Garlatti, V, Gaboriaud, C. | | Deposit date: | 2006-08-11 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
Embo J., 26, 2007
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6ZR3
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6ZR4
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4M7H
 | | Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CALCIUM ION, ... | | Authors: | Shrive, A.K, Greenhough, T.J, Holmskov, U. | | Deposit date: | 2013-08-12 | | Release date: | 2013-12-11 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the Tetrameric Fibrinogen-like Recognition Domain of Fibrinogen C Domain Containing 1 (FIBCD1) Protein.
J.Biol.Chem., 289, 2014
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1JC9
 | | TACHYLECTIN 5A FROM TACHYPLEUS TRIDENTATUS (JAPANESE HORSESHOE CRAB) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, techylectin-5A | | Authors: | Kairies, N, Beisel, H.-G, Fuentes-Prior, P, Tsuda, R, Muta, T, Iwanaga, S, Bode, W, Huber, R, Kawabata, S. | | Deposit date: | 2001-06-08 | | Release date: | 2001-11-28 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems.
Proc.Natl.Acad.Sci.USA, 98, 2001
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2FIB
 | | RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) COMPLEXED TO THE PEPTIDE GLY-PRO-ARG-PRO AT PH 6.0 | | Descriptor: | CALCIUM ION, FIBRINOGEN, GLY-PRO-ARG-PRO | | Authors: | Pratt, K.P, Cote, H.C.F, Chung, D.W, Stenkamp, R.E, Davie, E.W. | | Deposit date: | 1997-06-03 | | Release date: | 1997-10-15 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
Proc.Natl.Acad.Sci.USA, 94, 1997
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6EUA
 | | The fibrinogen-like domain of human Angptl3 | | Descriptor: | Angiopoietin-related protein 3 | | Authors: | Biterova, E.I, Esmaeeli, M.E, Alanen, H.I, Saaranen, M, Ruddock, L.W. | | Deposit date: | 2017-10-30 | | Release date: | 2018-05-09 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease.
Sci Rep, 8, 2018
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4EPU
 | | Ang1 fibrinogen-related domain (FReD) | | Descriptor: | Angiopoietin-1, CALCIUM ION | | Authors: | Yeykal, C.C, Adams, E.J. | | Deposit date: | 2012-04-17 | | Release date: | 2013-04-17 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | Biochemical and structural characterization of the Ang1 fibrinogen-related domain
To be Published
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4M7F
 | | Crystal structure of tetrameric fibrinogen-like recognition domain of FIBCD1 with bound ManNAc | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Shrive, A.K, Greenhough, T.J, Holmskov, U. | | Deposit date: | 2013-08-12 | | Release date: | 2013-12-11 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of the Tetrameric Fibrinogen-like Recognition Domain of Fibrinogen C Domain Containing 1 (FIBCD1) Protein.
J.Biol.Chem., 289, 2014
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1FIB
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1FID
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1FZD
 | | STRUCTURE OF RECOMBINANT ALPHAEC DOMAIN FROM HUMAN FIBRINOGEN-420 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Spraggon, G, Applegate, D, Everse, S.J, Zhang, J.-Z, Veerapandian, L, Redman, C, Doolittle, R.F, Grieninger, G. | | Deposit date: | 1998-06-22 | | Release date: | 1998-08-19 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of a recombinant alphaEC domain from human fibrinogen-420.
Proc.Natl.Acad.Sci.USA, 95, 1998
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3FIB
 | | RECOMBINANT HUMAN GAMMA-FIBRINOGEN CARBOXYL TERMINAL FRAGMENT (RESIDUES 143-411) BOUND TO CALCIUM AT PH 6.0: A FURTHER REFINEMENT OF PDB ENTRY 1FIB, AND DIFFERS FROM 1FIB BY THE MODELLING OF A CIS PEPTIDE BOND BETWEEN RESIDUES K338 AND C339 | | Descriptor: | CALCIUM ION, FIBRINOGEN GAMMA CHAIN RESIDUES | | Authors: | Pratt, K.P, Cote, H.C.F, Chung, D.W, Stenkamp, R.E, Davie, E.W. | | Deposit date: | 1997-07-14 | | Release date: | 1997-09-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro.
Proc.Natl.Acad.Sci.USA, 94, 1997
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4R9J
 | | L-ficolin complexed to glucosamine-6-sulfate | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, ACETATE ION, ... | | Authors: | Laffly, E, Lacroix, M, Martin, L, Vassal-Stermann, E, Thielens, N, Gaboriaud, C. | | Deposit date: | 2014-09-05 | | Release date: | 2014-11-05 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Human ficolin-2 recognition versatility extended: An update on the binding of ficolin-2 to sulfated/phosphated carbohydrates.
Febs Lett., 588, 2014
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6U0A
 | | Human Angiopoietin-Like 4 C-Terminal Domain (cANGPTL4) with Glycerol | | Descriptor: | Angiopoietin-related protein 4, GLYCEROL | | Authors: | Tarver, C.L, Yuan, Q, Singhal, A.J, Ramaker, R, Cooper, S, Pusey, M.L. | | Deposit date: | 2019-08-14 | | Release date: | 2019-10-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | Crystal Structures of Angiopoietin-Like 4 C-Terminal Domain (cANGPTL4) Reveal a Binding Pocket with Multiple Ligands
To Be Published
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2J3U
 | | L-ficolin complexed to galactose | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Garlatti, V, Gaboriaud, C. | | Deposit date: | 2006-08-23 | | Release date: | 2007-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
Embo J., 26, 2007
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4WN0
 | | Xenopus laevis embryonic epidermal lectin in complex with glycerol phosphate | | Descriptor: | CALCIUM ION, PENTAETHYLENE GLYCOL, PHOSPHATE ION, ... | | Authors: | Wangkanont, K, Kiessling, L.L, Forest, K.T. | | Deposit date: | 2014-10-10 | | Release date: | 2016-01-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.
J.Biol.Chem., 291, 2016
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