PDB: 117 件ウェブページステータス検索Chemie searchBIRD

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3AV5	Crystal structure of mouse DNA methyltransferase 1 with AdoHcy 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. 登録日 2011-02-22 公開日 2011-05-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
3AV6	Crystal structure of mouse DNA methyltransferase 1 with AdoMet 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYLMETHIONINE, ZINC ION 著者 Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S. 登録日 2011-02-22 公開日 2011-05-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). Proc.Natl.Acad.Sci.USA, 108, 2011
3EEO	M. HhaI co-crystallized with synthetic dsDNA containing a propane diol in place of the deoxycytidine residue targeted for methylation. 分子名称: 5'-D(P*DCP*DCP*DAP*DTP*DGP*DCP*DGP*DCP*DTP*DGP*DAP*DC)-3', 5'-D(P*DGP*DTP*DCP*DAP*DGP*(PDI)P*DGP*DCP*DAP*DTP*DGP*DG)-3', Modification methylase HhaI, ... 著者 Porta, J.C, Christman, J.K, Borgstahl, G.E.O. 登録日 2008-09-05 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 M. HhaI co-crystallized with synthetic dsDNA containing a propane diol in place of the deoxycytidine residue targeted for methylation. To be Published
3G7U	Crystal structure of putative DNA modification methyltransferase encoded within prophage Cp-933R (E.coli) 分子名称: CHLORIDE ION, Cytosine-specific methyltransferase, GLYCEROL 著者 Patskovsky, Y, Ramagopal, U.A, Toro, R, Gilmore, M, Iizuka, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-02-10 公開日 2009-02-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of DNA Modification Methyltransferase Encoded within Prophage Cp-933R (E.coli) To be Published
3MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY 分子名称: DNA (5'-D(*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... 著者 O'Gara, M, Klimasauskas, S, Roberts, R.J, Cheng, X. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
3PT6	Crystal structure of mouse DNMT1(650-1602) in complex with DNA 分子名称: DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ... 著者 Song, J, Patel, D.J. 登録日 2010-12-02 公開日 2010-12-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3PT9	Crystal structure of mouse DNMT1(731-1602) in the free state 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Song, J, Patel, D.J. 登録日 2010-12-02 公開日 2010-12-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3PTA	Crystal structure of human DNMT1(646-1600) in complex with DNA 分子名称: DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (cytosine-5)-methyltransferase 1, ... 著者 Song, J, Patel, D.J. 登録日 2010-12-02 公開日 2010-12-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331, 2011
3QV2	Structure Analysis of Entamoeba histolytica methyltransferase EhMeth 分子名称: 5-cytosine DNA methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION 著者 Schulz, E.C, Roth, H.M, Ankri, S, Ficner, R. 登録日 2011-02-25 公開日 2012-04-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure Analysis of Entamoeba histolytica Methyltransferase To be Published
3SWR	Structure of human DNMT1 (601-1600) in complex with Sinefungin 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (cytosine-5)-methyltransferase 1, ... 著者 Hashimoto, H, Cheng, X. 登録日 2011-07-14 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure of human DNMT1 (residues 600-1600) in complex with Sinefungin To be Published
3UBT	Crystal Structure of C71S Mutant of DNA Cytosine-5 Methyltransferase M.HaeIII Bound to DNA 分子名称: 5'-D(*TP*GP*GP*CP*CP*A)-3', ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Verdine, G.L, Didovyk, A. 登録日 2011-10-24 公開日 2012-10-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Structural origins of DNA target selection and nucleobase extrusion by a DNA Cytosine methyltransferase. J.Biol.Chem., 287, 2012
4DA4	Structure of mouse DNMT1 (731-1602) bound to hemimethylated CpG DNA 分子名称: CITRIC ACID, DNA (cytosine-5)-methyltransferase 1, DNA_LOWER_STRAND, ... 著者 Song, J, Patel, D.J. 登録日 2012-01-12 公開日 2012-02-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Based Mechanistic Insights into DNMT1-Mediated Maintenance DNA Methylation. Science, 335, 2012
4DKJ	CpG specific methyltransferase in complex with target DNA 分子名称: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(C37)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ... 著者 Wojciechowski, M, Czapinska, H, Bochtler, M. 登録日 2012-02-03 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI. Proc.Natl.Acad.Sci.USA, 110, 2013
4FSX	crystal structure of Se-substituted Zea mays ZMET2 in complex with SAH 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE 著者 Du, J, Patel, D.J. 登録日 2012-06-27 公開日 2012-10-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT2	crystal structure of Zea mays ZMET2 in complex H3(1-15)K9me2 peptide and SAH 分子名称: DNA (cytosine-5)-methyltransferase 1, H3 peptide, S-ADENOSYL-L-HOMOCYSTEINE 著者 Du, J, Patel, D.J. 登録日 2012-06-27 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4FT4	crystal structure of Zea mays ZMET2 in complex H3(1-32)K9me2 peptide and SAH 分子名称: DNA (cytosine-5)-methyltransferase 1, H3(1-32)K9me2 peptide, S-ADENOSYL-L-HOMOCYSTEINE 著者 Du, J, Patel, D.J. 登録日 2012-06-27 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants. Cell(Cambridge,Mass.), 151, 2012
4H0N	Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant 分子名称: CALCIUM ION, DNMT2, S-ADENOSYL-L-HOMOCYSTEINE 著者 Li, S, Du, J, Yang, H, Yin, J, Zhong, J, Ding, J. 登録日 2012-09-09 公開日 2012-11-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.712 Å) 主引用文献 Functional and structural characterization of DNMT2 from Spodoptera frugiperda. J Mol Cell Biol, 5, 2013
4MHT	TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY 分子名称: DNA (5'-D(*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ... 著者 Cheng, X. 登録日 1996-07-24 公開日 1997-01-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes. J.Mol.Biol., 261, 1996
4ONJ	Crystal structure of the catalytic domain of ntDRM 分子名称: DNA methyltransferase, SINEFUNGIN 著者 Du, J, Patel, D.J. 登録日 2014-01-28 公開日 2014-06-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.807 Å) 主引用文献 Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4ONQ	Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant 分子名称: DNA methyltransferase, SINEFUNGIN 著者 Du, J, Patel, D.J. 登録日 2014-01-28 公開日 2014-06-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases. Cell(Cambridge,Mass.), 157, 2014
4U7P	Crystal structure of DNMT3A-DNMT3L complex 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.821 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4U7T	Crystal structure of DNMT3A-DNMT3L in complex with histone H3 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4WXX	The crystal structure of human DNMT1(351-1600) 分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Zhang, Z.M, Song, J. 登録日 2014-11-14 公開日 2015-07-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.622 Å) 主引用文献 Crystal Structure of Human DNA Methyltransferase 1. J.Mol.Biol., 427, 2015
4YOC	Crystal Structure of human DNMT1 and USP7/HAUSP complex 分子名称: DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION 著者 Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. 登録日 2015-03-11 公開日 2015-05-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.916 Å) 主引用文献 Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun, 6, 2015
5CIY	Structural basis of the recognition of H3K36me3 by DNMT3B PWWP domain 分子名称: DNA (5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3'), Modification methylase HhaI, ... 著者 Rondelet, G, DAL MASO, T, Willems, L, Wouters, J. 登録日 2015-07-13 公開日 2016-03-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.594 Å) 主引用文献 Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B. J.Struct.Biol., 194, 2016

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