PDB: 367 件ウェブページステータス検索Chemie searchBIRD

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5B4V	Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and an inhibitor methylmalonate 分子名称: 3-hydroxybutyrate dehydrogenase, CHLORIDE ION, METHYLMALONIC ACID, ... 著者 Kanazawa, H, Tsunoda, M, Hoque, M.M, Suzuki, K, Yamamoto, T, Takenaka, A. 登録日 2016-04-19 公開日 2016-08-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase Acta Crystallogr.,Sect.F, 72, 2016
5B4T	Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and a substrate D-3-hydroxybutyrate 分子名称: (3R)-3-hydroxybutanoic acid, 3-hydroxybutyrate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Kanazawa, H, Tsunoda, M, Hoque, M.M, Suzuki, K, Yamamoto, T, Takenaka, A. 登録日 2016-04-19 公開日 2016-08-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase Acta Crystallogr.,Sect.F, 72, 2016
5B4U	Crystal structure of D-3-hydroxybutyrate dehydrogenase from Alcaligenes faecalis complexed with NAD+ and an inhibitor malonate 分子名称: 3-hydroxybutyrate dehydrogenase, CHLORIDE ION, MALONIC ACID, ... 著者 Kanazawa, H, Tsunoda, M, Hoque, M.M, Suzuki, K, Yamamoto, T, Takenaka, A. 登録日 2016-04-19 公開日 2016-08-17 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase Acta Crystallogr.,Sect.F, 72, 2016
5L53	Menthone neomenthol reductase from Mentha piperita in complex with NADP 分子名称: (-)-menthone:(+)-neomenthol reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-05-27 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
5L4S	Isopiperitenone reductase from Mentha piperita in complex with NADP and beta-Cyclocitral 分子名称: (-)-isopiperitenone reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, beta-cyclocitral 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-05-26 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
5L51	Menthone neomenthol reductase from Mentha piperita 分子名称: (-)-menthone:(+)-neomenthol reductase 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-05-27 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
5LDG	Isopiperitenone reductase from Mentha piperita in complex with Isopiperitenone and NADP 分子名称: (-)-Isopiperitenone, (-)-isopiperitenone reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-06-26 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
5LCX	Isopiperitenone reductase from Mentha piperita in complex with NADP 分子名称: (-)-isopiperitenone reductase, (4S)-2-METHYL-2,4-PENTANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. 登録日 2016-06-22 公開日 2016-08-31 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.709 Å) 主引用文献 Pinpointing a Mechanistic Switch Between Ketoreduction and "Ene" Reduction in Short-Chain Dehydrogenases/Reductases. Angew.Chem.Int.Ed.Engl., 55, 2016
5JO9	Structural characterization of the thermostable Bradyrhizobium japonicum d-sorbitol dehydrogenase 分子名称: PHOSPHATE ION, Ribitol 2-dehydrogenase, sorbitol 著者 Fredslund, F, Otten, H, Navarro Poulsen, J.-C, Lo Leggio, L. 登録日 2016-05-02 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.894 Å) 主引用文献 Structural characterization of the thermostable Bradyrhizobium japonicumD-sorbitol dehydrogenase. Acta Crystallogr F Struct Biol Commun, 72, 2016
5TQV	Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans 分子名称: NADPH-dependent carbonyl reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-10-24 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans TO BE PUBLISHED
5ILO	Crystal structure of photoreceptor dehydrogenase from Drosophila melanogaster 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Photoreceptor dehydrogenase, isoform C 著者 Hofmann, L, Tsybovsky, Y, Banerjee, S. 登録日 2016-03-04 公開日 2016-11-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family. Biochemistry, 55, 2016
5ILG	Crystal structure of photoreceptor dehydrogenase from Drosophila melanogaster 分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Hofmann, L, Tsybovsky, Y, Banerjee, S. 登録日 2016-03-04 公開日 2016-11-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family. Biochemistry, 55, 2016
5U1P	Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans in complex with NADP 分子名称: 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-dependent carbonyl reductase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-11-28 公開日 2016-12-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of NADP-dependent carbonyl reductase from Burkholderia multivorans in complex with NADP TO BE PUBLISHED
5U4S	Crystal structure of a Short chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP. 分子名称: BENZOIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHOSPHATE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-12-06 公開日 2017-01-18 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of a Short chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP to be published
5U2W	Crystal structure of a Short chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP 分子名称: 1,2-ETHANEDIOL, IMIDAZOLE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-12-01 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of a Short chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP to be published
5U9P	Crystal structure of a gluconate 5-dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP and tartrate 分子名称: 1,2-ETHANEDIOL, Gluconate 5-dehydrogenase, L(+)-TARTARIC ACID, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-12-17 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of a gluconate 5-dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP and tartrate TO BE PUBLISHED
5UZX	Crystal Structure of Putative short-chain dehydrogenase/reductase from Burkholderia multivorans with bound NADP 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-02-27 公開日 2017-03-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of Putative short-chain dehydrogenase/reductase from Burkholderia multivorans with bound NADP to be published
5GT9	The X-ray structure of 7beta-hydroxysteroid dehydrogenase 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, short chain dehydrogenase/reductase family protein 著者 Wang, F, Wang, R, Lv, Z, Chen, Q, Huo, X. 登録日 2016-08-19 公開日 2017-05-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of NADP(+)-bound 7 beta-hydroxysteroid dehydrogenase reveals two cofactor-binding modes Acta Crystallogr F Struct Biol Commun, 73, 2017
5VML	Crystal Structure of Acetoacetyl-CoA Reductase from Burkholderia Pseudomallei 1710b with bound NADP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Acetoacetyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2017-04-27 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Acetoacetyl-CoA Reductase from Burkholderia Pseudomallei 1710b with bound NADP to be published
5WQP	Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition II) 分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE, PHOSPHATE ION, ... 著者 Li, S, Wang, Y, Bartlam, M. 登録日 2016-11-27 公開日 2017-10-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1. FEBS Lett., 591, 2017
5WQN	Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 (condition II) 分子名称: Probable dehydrogenase 著者 Li, S, Wang, Y, Bartlam, M. 登録日 2016-11-27 公開日 2017-10-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1. FEBS Lett., 591, 2017
5WQO	Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 in complex with NADP (condition I) 分子名称: 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Probable dehydrogenase, ... 著者 Li, S, Wang, Y, Bartlam, M. 登録日 2016-11-27 公開日 2017-10-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1. FEBS Lett., 591, 2017
5PGU	CRYSTAL STRUCTURE OF 11BETA-HSD1 DOUBLE MUTANT (L262R, F278E) COMPLEXED WITH 2-[2-(4-fluorophenyl)-2-adamantyl]-1-(3-methoxyazetidin-1-yl)ethanone 分子名称: 2-[2-(4-fluorophenyl)-2-adamantyl]-1-(3-methoxyazetidin-1-yl)ethanone, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sheriff, S. 登録日 2017-02-06 公開日 2017-11-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. J. Med. Chem., 60, 2017
5PGX	CRYSTAL STRUCTURE OF 11BETA-HSD1 DOUBLE MUTANT (L262R, F278E) COMPLEXED WITH 2-(2-BENZYL-6-HYDROXYADAMANTAN-2-YL)-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE 分子名称: 2-(2-BENZYL-6-HYDROXYADAMANTAN-2-YL)-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sheriff, S. 登録日 2017-02-06 公開日 2017-11-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. J. Med. Chem., 60, 2017
5PGY	CRYSTAL STRUCTURE OF 11BETA-HSD1 DOUBLE MUTANT (L262R, F278E) COMPLEXED WITH 2-[(5R,7S)-6-HYDROXY-2-PHENYLADAMANTAN-2-YL]-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE (BMS-816336) 分子名称: 2-[(5R,7S)-6-HYDROXY-2-PHENYLADAMANTAN-2-YL]-1-(3-HYDROXYAZETIDIN-1-YL)ETHAN-1-ONE, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sheriff, S. 登録日 2017-02-06 公開日 2017-11-01 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11 beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor. J. Med. Chem., 60, 2017

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