PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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7WY3	Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 F87V Mutant Haem Domain with N-(5-Cyclohexyl)valeroyl-L-Phenylalanine in complex with Styrene 分子名称: (2~{S})-2-(5-cyclohexylpentanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, ... 著者 Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O. 登録日 2022-02-15 公開日 2023-01-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
7WY1	Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styerene 分子名称: (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, Oxomolybdenum Mesoporphyrin IX, ... 著者 Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O. 登録日 2022-02-15 公開日 2023-01-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
7WY2	Structure of the Oxomolybdenum Mesoporphyrin IX-Reconstituted CYP102A1 F87A Mutant Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styrene 分子名称: (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, ... 著者 Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O. 登録日 2022-02-15 公開日 2023-01-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
7WY4	Structure of the CYP102A1 F87A Haem Domain with N-Enanthyl-L-Prolyl-L-Phenylalanine in complex with Styrene 分子名称: (2S)-2-[[(2S)-1-heptylpyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, CHLORIDE ION, ... 著者 Suzuki, K, Stanfield, J.K, Shisaka, Y, Omura, K, Kasai, C, Sugimoto, H, Shoji, O. 登録日 2022-02-15 公開日 2023-01-04 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
7R3U	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: 1-[4-(1,2,3-thiadiazol-4-yl)phenyl]methanamine, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Snee, M, Katariya, M, Leys, D, Levy, C. 登録日 2022-02-07 公開日 2023-02-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7R1I	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-02-03 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7TTB	P450 (OxyA) from kistamicin biosynthesis, Y99F mutant 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.801592 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTQ	P450 (OxyA) from kistamicin biosynthesis, imidazole complex 分子名称: GLYCEROL, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTA	P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation, attenuated beam 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTP	P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation 分子名称: GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TTO	P450 (OxyA) from kistamicin biosynthesis, mixed heme conformation 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 hydroxylase 著者 Greule, A, Izore, T, Cryle, M.J. 登録日 2022-02-01 公開日 2022-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Cytochrome P450 OxyA from the Kistamicin Biosynthesis Cyclization Cascade is Highly Sensitive to Oxidative Damage. Front Chem, 10, 2022
7TRU	The crystal structure of WT CYP199A4 bound to 4-(thiophen-2-yl)benzoic acid 分子名称: 4-(thiophen-2-yl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-01-31 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.454 Å) 主引用文献 The Oxidation of Oxygen and Sulfur-Containing Heterocycles by Cytochrome P450 Enzymes. Chemistry, 29, 2023
7TRT	The crystal structure of CYP199A4 bound to 4-(furan-2-yl)benzoic acid 分子名称: 4-(furan-2-yl)benzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M.N, Bell, S.G. 登録日 2022-01-30 公開日 2023-03-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 The Oxidation of Oxygen and Sulfur-Containing Heterocycles by Cytochrome P450 Enzymes. Chemistry, 29, 2023
7TQM	The crystal structure of D251N CYP199A4 bound to 4-methylthiobenzoic acid 分子名称: 4-methylsulfanylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-26 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.438 Å) 主引用文献 Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions. Chemistry, 28, 2022
7TP5	The crystal structure of T252E CYP199A4 bound to 4-ethylthiobenzoic acid 分子名称: 4-(ethylsulfanyl)benzoic acid, ACETATE ION, CHLORIDE ION, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-25 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.655 Å) 主引用文献 Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions. Chemistry, 28, 2022
7TP6	The crystal structure of T252E CYP199A4 bound to 4-methylthiobenzoic acid 分子名称: 4-methylsulfanylbenzoic acid, ACETATE ION, CHLORIDE ION, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-25 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.655 Å) 主引用文献 Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions. Chemistry, 28, 2022
7QWN	Crystal structure of CYP125 from Mycobacterium tuberculosis in complex with an inhibitor 分子名称: CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... 著者 Snee, M, Katariya, M, Levy, C, Leys, D. 登録日 2022-01-25 公開日 2023-02-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis. Chemistry, 29, 2023
7TNF	The crystal structure of F298V CYP199A4 bound to 4-phenylbenzoic acid 分子名称: CHLORIDE ION, Cytochrome P450, MAGNESIUM ION, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-21 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.539 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
7TNU	The crystal structure of F298V CYP199A4 bound to 4-cyclohexylbenzoic acid 分子名称: 4-cyclohexylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-21 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.584 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
7TND	The crystal structure of CYP199A4 bound to 4-phenoxybenzoic acid 分子名称: 4-phenoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-20 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.825 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
7TLO	X-ray crystal structure of substrate free cytochrome P450 CYP142A3 from Mycobacterium Marinum 分子名称: ACETATE ION, Cytochrome P450 142A3, PROTOPORPHYRIN IX CONTAINING FE 著者 Ghith, A, Bruning, J.B, Bell, S.G. 登録日 2022-01-18 公開日 2022-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum. Acs Infect Dis., 8, 2022
7QQ7	Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor at partial occupancy with PEG 分子名称: ACETATE ION, BROMIDE ION, CHLORIDE ION, ... 著者 Snee, M, Levy, C, Kavanagh, M. 登録日 2022-01-06 公開日 2023-01-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with an inhibitor at partial occupancy with PEG To Be Published
7TEF	Cytochrome P450 14 alpha-sterol demethylase CYP51 from Mycobacterium marinum 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450 51B1 Cyp51B1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Mohamed, H.A, Bruning, J.B, Bell, S.G. 登録日 2022-01-04 公開日 2022-11-30 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis. J.Steroid Biochem.Mol.Biol., 221, 2022
7WG0	Structure of the Manganese Protoporphyrin IX-Reconstituted CYP102A1 Heme Domain with N-palmitoyl-L-phenylalanine 分子名称: (2~{S})-2-(hexadecanoylamino)-3-phenyl-propanoic acid, Bifunctional cytochrome P450/NADPH--P450 reductase, MANGANESE PROTOPORPHYRIN IX 著者 Keita, O, Osami, S, Yuichiro, A, Hiroshi, S. 登録日 2021-12-27 公開日 2023-01-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the Manganese Protoporphyrin IX-Reconstituted CYP102A1 Heme Domain with N-palmitoyl-L-phenylalanine To Be Published
7WEX	The crystal structure of substrate-free CYP107X1 from Streptomyces avermitilis 分子名称: Cytochrome P450 hydroxylase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Xu, L.-H, Lin, S, Gao, L. 登録日 2021-12-24 公開日 2022-06-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The 16 alpha-Hydroxylation of Progesterone by Cytochrome P450 107X1 from Streptomyces avermitilis. Chem.Biodivers., 19, 2022

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