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7P0B
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BU of 7p0b by Molmil
Human mitochondrial Lon protease without substrate
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Valentin Gese, G, Shahzad, S, Hallberg, B.M.
登録日2021-06-29
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P0M
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BU of 7p0m by Molmil
Human mitochondrial Lon protease with substrate in the ATPase and protease domains
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
著者Valentin Gese, G, Shahzad, S, Hallberg, B.M.
登録日2021-06-30
公開日2021-08-11
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献A dual allosteric pathway drives human mitochondrial Lon
To Be Published
7P6U
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BU of 7p6u by Molmil
Lon protease from Thermus Thermophilus
分子名称: (UNK)(UNK)(UNK)(UNK)(UNK)(UNK)(UNK), Lon protease, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Coscia, F, Lowe, J.
登録日2021-07-18
公開日2021-10-27
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of the full-length Lon protease from Thermus thermophilus.
Febs Lett., 595, 2021
7PUX
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BU of 7pux by Molmil
Structure of p97 N-D1(L198W) in complex with Fragment TROLL2
分子名称: (1S)-2-amino-1-(4-bromophenyl)ethan-1-ol, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Bothe, S, Schindelin, H.
登録日2021-10-01
公開日2022-12-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97
Commun Chem, 5, 2022
7PX9
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BU of 7px9 by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state A)
分子名称: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Jomaa, A, Kavalchuk, M, Weber-Ban, E.
登録日2021-10-08
公開日2022-01-19
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXA
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BU of 7pxa by Molmil
Open-gate mycobacterium 20S CP proteasome in complex MPA - global 3D refinement
分子名称: AAA ATPase forming ring-shaped complexes, Proteasome subunit alpha, Proteasome subunit beta
著者Jomaa, A, Kavalchuk, M, Weber-Ban, E.
登録日2021-10-08
公開日2022-01-19
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXB
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BU of 7pxb by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase - focused 3D refinement (state B)
分子名称: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Jomaa, A, Kavalchuk, M, Weber-Ban, E.
登録日2021-10-08
公開日2022-01-19
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXC
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BU of 7pxc by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state A)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Jomaa, A, Kavalchuk, M, Weber-Ban, E.
登録日2021-10-08
公開日2022-01-19
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7PXD
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BU of 7pxd by Molmil
Substrate-engaged mycobacterial Proteasome-associated ATPase in complex with open-gate 20S CP - composite map (state B)
分子名称: AAA ATPase forming ring-shaped complexes, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Jomaa, A, Kavalchuk, M, Weber-Ban, E.
登録日2021-10-08
公開日2022-01-19
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of prokaryotic ubiquitin-like protein engagement and translocation by the mycobacterial Mpa-proteasome complex.
Nat Commun, 13, 2022
7QO4
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BU of 7qo4 by Molmil
26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS)
分子名称: 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7QO5
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BU of 7qo5 by Molmil
26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7QO6
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BU of 7qo6 by Molmil
26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7QXN
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BU of 7qxn by Molmil
Proteasome-ZFAND5 Complex Z+A state
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-26
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QXP
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BU of 7qxp by Molmil
Proteasome-ZFAND5 Complex Z+B state
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-26
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QXU
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BU of 7qxu by Molmil
Proteasome-ZFAND5 Complex Z+C state
分子名称: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-27
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QXW
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BU of 7qxw by Molmil
Proteasome-ZFAND5 Complex Z+D state
分子名称: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-27
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QXX
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BU of 7qxx by Molmil
Proteasome-ZFAND5 Complex Z+E state
分子名称: 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, 26S protease regulatory subunit 7, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-27
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QY7
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BU of 7qy7 by Molmil
Proteasome-ZFAND5 Complex Z-A state
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-27
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QYA
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BU of 7qya by Molmil
Proteasome-ZFAND5 Complex Z-B state
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-27
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7QYB
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BU of 7qyb by Molmil
Proteasome-ZFAND5 Complex Z-C state
分子名称: 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ...
著者Zhu, Y, Lu, Y.
登録日2022-01-27
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Mechanism of 26S proteasome activation by the 19S-interacting protein ZFAND5
To Be Published
7R7S
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BU of 7r7s by Molmil
p47-bound p97-R155H mutant with ATPgammaS
分子名称: NSFL1 cofactor p47, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L.
登録日2021-06-25
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
7R7T
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BU of 7r7t by Molmil
p47-bound p97-R155H mutant with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, NSFL1 cofactor p47, Transitional endoplasmic reticulum ATPase
著者Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L.
登録日2021-06-25
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
7R7U
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BU of 7r7u by Molmil
D1 and D2 domain structure of the p97(R155H)-p47 complex
分子名称: Transitional endoplasmic reticulum ATPase
著者Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Poh, Y.-P, Chou, T.-F, Chiu, P.-L.
登録日2021-06-25
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes.
Int J Mol Sci, 22, 2021
7RL6
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BU of 7rl6 by Molmil
Cryo-EM structure of human p97-R155H mutant bound to ADP.
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S.
登録日2021-07-23
公開日2021-09-22
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021
7RL7
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BU of 7rl7 by Molmil
Cryo-EM structure of human p97-R155H mutant bound to ATPgS.
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S.
登録日2021-07-23
公開日2021-09-22
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation.
J.Biol.Chem., 297, 2021

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件を2024-05-15に公開中

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