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6CJH
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BU of 6cjh by Molmil
Co-crystal structure of MNK2 in complex with an inhibitor
Descriptor: 3-phenyl-5-(pyridin-4-yl)-1H-indazole, MAP kinase-interacting serine/threonine-protein kinase 2, ZINC ION
Authors:Han, Q.
Deposit date:2018-02-26
Release date:2018-05-09
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.
J. Med. Chem., 61, 2018
4NV2
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BU of 4nv2 by Molmil
C50A mutant of Synechococcus VKOR, C2221 crystal form
Descriptor: UBIQUINONE-10, VKORC1/thioredoxin domain protein
Authors:Liu, S, Cheng, W, Fowle Grider, R, Shen, G, Li, W.
Deposit date:2013-12-04
Release date:2014-02-12
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer.
Nat Commun, 5, 2014
4BIU
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BU of 4biu by Molmil
Crystal structure of CpxAHDC (orthorhombic form 1)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, SENSOR PROTEIN CPXA, SULFATE ION
Authors:Mechaly, A.E, Sassoon, N, Betton, J.M, Alzari, P.M.
Deposit date:2013-04-13
Release date:2014-02-12
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
Plos Biol., 12, 2014
6EYC
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BU of 6eyc by Molmil
Re-refinement of the MCM2-7 double hexamer using ISOLDE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ...
Authors:Croll, T.I.
Deposit date:2017-11-11
Release date:2018-06-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps.
Acta Crystallogr D Struct Biol, 74, 2018
4EIW
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BU of 4eiw by Molmil
Whole cytosolic region of atp-dependent metalloprotease FtsH (G399L)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH
Authors:Suno, R, Niwa, H, Tsuchiya, D, Yoshida, M, Morikawa, K.
Deposit date:2012-04-06
Release date:2012-06-06
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structure of the whole cytosolic region of ATP-dependent protease FtsH
Mol.Cell, 22, 2006
4FGU
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BU of 4fgu by Molmil
Crystal structure of prolegumain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Legumain
Authors:Dall, E, Brandstetter, H.
Deposit date:2012-06-05
Release date:2013-07-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation.
Proc.Natl.Acad.Sci.USA, 110, 2013
5UCG
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BU of 5ucg by Molmil
Structure of the PP2C Phosphatase Domain and a Fragment of the Regulatory Domain of the Cell Fate Determinant SpoIIE from Bacillus Subtilis
Descriptor: Stage II sporulation protein E
Authors:Bradshaw, N, Levdikov, V, Zimanyi, C, Gaudet, R, Wilkinson, A, Losick, R.
Deposit date:2016-12-22
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.906 Å)
Cite:A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
7BL1
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BU of 7bl1 by Molmil
human complex II-BATS bound to membrane-attached Rab5a-GTP
Descriptor: Beclin-1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Tremel, S, Morado, D.R, Kovtun, O, Williams, R.L, Briggs, J.A.G, Munro, S, Ohashi, Y, Bertram, J, Perisic, O.
Deposit date:2021-01-17
Release date:2021-03-03
Last modified:2021-03-24
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
Nat Commun, 12, 2021
2L9G
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BU of 2l9g by Molmil
Solution structure of AS1p-Tar in 10% negatively charged bicelles
Descriptor: Methyl-accepting chemotaxis protein II
Authors:Unnerstale, S, von Heijne, G, Draheim, R.R, Maler, L.
Deposit date:2011-02-09
Release date:2011-09-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of AS1-membrane interactions from a subset of HAMP domains
Biochim.Biophys.Acta, 1808, 2011
2LP0
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BU of 2lp0 by Molmil
The solution structure of homeodomain-protein complex
Descriptor: Geminin, Homeobox protein Hox-C9
Authors:Liu, C, Zhou, B, Xu, Z, Zhu, G.
Deposit date:2012-01-29
Release date:2012-06-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
Proc.Natl.Acad.Sci.USA, 2012
1TKQ
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BU of 1tkq by Molmil
SOLUTION STRUCTURE OF A LINKED UNSYMMETRIC GRAMICIDIN IN A MEMBRANE-ISOELECTRICAL SOLVENTS MIXTURE IN THE PRESENCE OF CsCl
Descriptor: GRAMICIDIN A, MINI-GRAMICIDIN A, SUCCINIC ACID
Authors:Xie, X, Al-Momani, L, Bockelmann, D, Griesinger, C, Koert, U.
Deposit date:2004-06-09
Release date:2004-07-13
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:An Asymmetric Ion Channel Derived from Gramicidin A. Synthesis, Function and NMR Structure.
FEBS J., 272, 2005
1ZY6
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BU of 1zy6 by Molmil
Membrane-bound dimer structure of Protegrin-1 (PG-1), a beta-Hairpin Antimicrobial Peptide in Lipid Bilayers from Rotational-Echo Double-Resonance Solid-State NMR
Descriptor: Protegrin 1
Authors:Wu, X, Mani, R, Tang, M, Buffy, J.J, Waring, A.J, Sherman, M.A, Hong, M.
Deposit date:2005-06-09
Release date:2006-06-13
Last modified:2022-03-02
Method:SOLID-STATE NMR
Cite:Membrane-Bound Dimer Structure of a beta-Hairpin Antimicrobial Peptide from Rotational-Echo Double-Resonance Solid-State NMR.
Biochemistry, 45, 2006
2GB8
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BU of 2gb8 by Molmil
Solution structure of the complex between yeast iso-1-cytochrome c and yeast cytochrome c peroxidase
Descriptor: Cytochrome c iso-1, Cytochrome c peroxidase, HEME C, ...
Authors:Volkov, A.N, Worrall, J.A.R, Ubbink, M.
Deposit date:2006-03-10
Release date:2006-11-21
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2N9U
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BU of 2n9u by Molmil
Solution NMR structure of Erythrobacter litoralis PhyR response regulator REC domain
Descriptor: Response regulator
Authors:Correa, F, Gardner, K.H.
Deposit date:2015-12-09
Release date:2016-09-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Basis of Mutual Domain Inhibition in a Bacterial Response Regulator.
Cell Chem Biol, 23, 2016
2JTI
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BU of 2jti by Molmil
Solution structure of the yeast iso-1-cytochrome c (T12A) : yeast cytochrome c peroxidase complex
Descriptor: Cytochrome c iso-1, Cytochrome c peroxidase, mitochondrial, ...
Authors:Ubbink, M, Volkov, A.N.
Deposit date:2007-08-01
Release date:2008-07-22
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:Shifting the equilibrium between the encounter state and the specific form of a protein complex by interfacial point mutations.
J.Am.Chem.Soc., 132, 2010
6H5H
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BU of 6h5h by Molmil
A computationally designed dRP lyase domain reconstructed from two heterologous fragments
Descriptor: polb4
Authors:ElGamacy, M, Coles, M, Lupas, A.N.
Deposit date:2018-07-24
Release date:2018-12-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Asymmetric protein design from conserved supersecondary structures.
J. Struct. Biol., 204, 2018

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