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6A5K
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BU of 6a5k by Molmil
Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1
Descriptor: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ...
Authors:Li, X, Du, J.
Deposit date:2018-06-24
Release date:2018-08-29
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7XUD
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BU of 7xud by Molmil
Structure of G9a in complex with compound 26a
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
Deposit date:2022-05-18
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XUA
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BU of 7xua by Molmil
Structure of G9a in complex with compound 10a
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ...
Authors:Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
Deposit date:2022-05-18
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XUC
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BU of 7xuc by Molmil
Structure of G9a in complex with compound 11a
Descriptor: 1,2-ETHANEDIOL, 3,6,6-trimethyl-4-oxidanylidene-~{N}-[(2~{S})-1-oxidanylidene-1-phenylazanyl-hexan-2-yl]-5,7-dihydro-1~{H}-indole-2-carboxamide, CHLORIDE ION, ...
Authors:Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
Deposit date:2022-05-18
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XUB
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BU of 7xub by Molmil
Structure of G9a in complex with compound 10d
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ...
Authors:Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
Deposit date:2022-05-18
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
4IUU
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BU of 4iuu by Molmil
Crystal structure of SHH1 SAWADEE domain in complex with H3K9me1 peptide
Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
Authors:Du, J, Patel, D.J.
Deposit date:2013-01-21
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUV
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BU of 4iuv by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide
Descriptor: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
Authors:Du, J, Patel, D.J.
Deposit date:2013-01-21
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
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数据于2024-05-01公开中

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