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7XW8

Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct 分子名称: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ... 著者 Oki, H. 登録日 2022-05-26 公開日 2022-10-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects. Eur.J.Med.Chem., 239, 2022