PDB: 446 件ウェブページステータス検索Chemie searchBIRD

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4FRG	Crystal structure of the cobalamin riboswitch aptamer domain 分子名称: Hydroxocobalamin, IRIDIUM (III) ION, MAGNESIUM ION, ... 著者 Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. 登録日 2012-06-26 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
4GMA	Crystal structure of the adenosylcobalamin riboswitch 分子名称: Adenosylcobalamin, Adenosylcobalamin riboswitch 著者 Reyes, F.E, Johnson, J.E, Polaski, J.T, Batey, R.T. 登録日 2012-08-15 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.94 Å) 主引用文献 B12 cofactors directly stabilize an mRNA regulatory switch. Nature, 492, 2012
5FJC	SAM-I riboswitch bearing the H. marismortui Kt-7 variant C-2bU 分子名称: BARIUM ION, MAGNESIUM ION, POTASSIUM ION, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2015-10-07 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
4MGN	Co-crystal structure of the G. kaustophilus glyQS T box riboswitch Stem I in complex with tRNA 分子名称: MAGNESIUM ION, glyQS T box riboswitch, tRNA-glycine 著者 Grigg, J.C, Ke, A. 登録日 2013-08-28 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Determinants for Geometry and Information Decoding of tRNA by T Box Leader RNA. Structure, 21, 2013
4TZX	Vibrio Vulnificus Adenine Riboswitch variant, grown in Mg2+ 分子名称: ADENINE, MAGNESIUM ION, Vibrio vulnificus Adenine Riboswitch 著者 Zhang, J, Ferre-D'Amare, A.R. 登録日 2014-07-11 公開日 2014-09-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
4TZY	Vibrio vulnificus Adenine Riboswitch Variant, grown in both Sr2+ and Mg2+ 分子名称: ADENINE, MAGNESIUM ION, STRONTIUM ION, ... 著者 Zhang, J, Ferre-D'Amare, A.R. 登録日 2014-07-11 公開日 2014-09-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Dramatic Improvement of Crystals of Large RNAs by Cation Replacement and Dehydration. Structure, 22, 2014
6CK4	G96A mutant of the PRPP riboswitch from T. mathranii bound to ppGpp 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5',3'-TETRAPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Reiss, C.W, Knappenberger, A.J, Strobel, S.A. 登録日 2018-02-27 公開日 2018-06-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.097 Å) 主引用文献 Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA. Elife, 7, 2018
6CK5	PRPP riboswitch from T. mathranii bound to PRPP 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, BARIUM ION, MAGNESIUM ION, ... 著者 Knappenberger, A.J, Reiss, C.W, Strobel, S.A. 登録日 2018-02-27 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA. Elife, 7, 2018
2LI4	Solution structure of a shortened antiterminator hairpin from a Mg2+ riboswitch 分子名称: RNA (32-MER) 著者 Korth, M.M.T, Sigel, R.K.O. 登録日 2011-08-22 公開日 2012-08-22 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of a shortened antiterminator hairpin from a Mg2+ riboswitch To be Published
6VWV	Transitional unit cell 2 of adenine riboswitch aptamer crystal phase transition upon ligand binding 分子名称: ADENINE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Stagno, J.R, Wang, Y.-X. 登録日 2020-02-20 公開日 2020-11-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Synchronous RNA conformational changes trigger ordered phase transitions in crystals. Nat Commun, 12, 2021
6VWT	Transitional unit cell 1 of adenine riboswitch aptamer crystal phase transition upon ligand binding 分子名称: ADENINE, MAGNESIUM ION, adenine riboswitch aptamer variant 著者 Stagno, J.R, Wang, Y.-X. 登録日 2020-02-20 公開日 2020-11-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Synchronous RNA conformational changes trigger ordered phase transitions in crystals. Nat Commun, 12, 2021
3TZR	Structure of a Riboswitch-like RNA-ligand complex from the Hepatitis C Virus Internal Ribosome Entry Site 分子名称: (8R)-8-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-1,7,8,9-tetrahydrochromeno[5,6-d]imidazol-2-amine, 5'-R(*CP*GP*AP*GP*GP*AP*AP*CP*UP*AP*CP*UP*GP*UP*CP*UP*UP*CP*CP*C)-3', 5'-R(*GP*GP*UP*CP*GP*UP*GP*CP*AP*GP*CP*CP*UP*CP*GP*G)-3', ... 著者 Dibrov, S.M, Ding, K, Brunn, N, Parker, M.A, Bergdahl, B.M, Wyles, D.L, Hermann, T. 登録日 2011-09-27 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.212 Å) 主引用文献 Structure of a Riboswitch in the Hepatitis C Virus Internal Ribosome Entry Site To be Published
6E1V	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 3: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine 分子名称: 2-[(9H-carbazol-3-yl)oxy]-N,N-dimethylethan-1-amine, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1S	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine 分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1T	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 1: 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[(dibenzo[b,d]furan-2-yl)oxy]ethan-1-amine, MAGNESIUM ION, ... 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1W	Crystal structure of a class I PreQ1 riboswitch complexed with PreQ1 分子名称: 2-amino-5-(aminomethyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, ACETATE ION, MAGNESIUM ION, ... 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
6E1U	Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound 2: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine 分子名称: 2-[(dibenzo[b,d]furan-2-yl)oxy]-N,N-dimethylethan-1-amine, MAGNESIUM ION, RNA (33-MER) 著者 Numata, T, Connelly, C.M, Schneekloth, J.S, Ferre-D'Amare, A.R. 登録日 2018-07-10 公開日 2019-04-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Synthetic ligands for PreQ1riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun, 10, 2019
1Y27	G-riboswitch-guanine complex 分子名称: Bacillus subtilis xpt, GUANINE 著者 Serganov, A, Yuan, Y.R, Patel, D.J. 登録日 2004-11-20 公開日 2004-12-28 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs Chem.Biol., 11, 2004
6BFB	Crystal structure of a F. nucleatum FMN riboswitch bound to WG-3 分子名称: 5-[(3S,4S)-3-(dimethylamino)-4-hydroxypyrrolidin-1-yl]-6-fluoro-4-methyl-8-oxo-3,4-dihydro-8H-1-thia-4,9b-diazacyclopenta[cd]phenalene-9-carboxylic acid, MAGNESIUM ION, RNA (54-MER), ... 著者 Rizvi, N.F, Fischmann, T.O. 登録日 2017-10-26 公開日 2018-02-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry. ACS Chem. Biol., 13, 2018
5BTP	Fusobacterium ulcerans ZTP riboswitch bound to ZMP 分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Jones, C.P, Ferre-D'Amare, A.R. 登録日 2015-06-03 公開日 2015-08-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.816 Å) 主引用文献 Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains. Nat.Struct.Mol.Biol., 22, 2015
6POM	Cryo-EM structure of the full-length Bacillus subtilis glyQS T-box riboswitch in complex with tRNA-Gly 分子名称: T-box GlyQS leader (155-MER), tRNAGly (75-MER) 著者 Li, S, Su, Z, Zhang, J, Chiu, W. 登録日 2019-07-04 公開日 2019-11-20 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions. Nat.Struct.Mol.Biol., 26, 2019
7E9E	Crystal structure of a class I PreQ1 riboswitch aptamer (ab13-14) complexed with a cognate ligand-derived photoaffinity probe 分子名称: 2-azanyl-5-[[2-(3-but-3-ynyl-1,2-diazirin-3-yl)ethylamino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, 33-mer RNA, MAGNESIUM ION, ... 著者 Numata, T, Schneekloth, J.S. 登録日 2021-03-04 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites. Nat Commun, 12, 2021
7E9I	Crystal structure of a class I PreQ1 riboswitch aptamer (wild-type) complexed with a cognate ligand-derived photoaffinity probe 分子名称: 2-azanyl-5-[[2-(3-but-3-ynyl-1,2-diazirin-3-yl)ethylamino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, 33-mer RNA, SULFATE ION 著者 Numata, T, Schneekloth, J.S. 登録日 2021-03-04 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A chemical probe based on the PreQ 1 metabolite enables transcriptome-wide mapping of binding sites. Nat Commun, 12, 2021
3UD4	The C92U mutant c-di-GMP-I riboswitch bound to GpA 分子名称: MAGNESIUM ION, RNA (5'-R(*GP*A)-3'), RNA (92-MER), ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012
3UD3	The C92U mutant c-di-GMP-I riboswitch bound to pGpA 分子名称: MAGNESIUM ION, RNA (5'-R(P*GP*A)-3'), RNA (92-MER), ... 著者 Smith, K.D, Strobel, S.A. 登録日 2011-10-27 公開日 2012-01-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry, 51, 2012

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