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2RLN
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THERMODYNAMIC AND STRUCTURAL CONSEQUENCES OF CHANGING A SULPHUR ATOM TO A METHYLENE GROUP IN THE M13NLE MUTATION IN RIBONUCLEASE S
Descriptor: RIBONUCLEASE, RIBONUCLEASE S (S-PROTEIN), SULFATE ION
Authors:Ratnaparkhi, G, Varadarajan, R.
Deposit date:1994-07-11
Release date:1994-11-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Thermodynamic and structural consequences of changing a sulfur atom to a methylene group in the M13Nle mutation in ribonuclease-S.
Biochemistry, 33, 1994
2RNS
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REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES
Descriptor: RIBONUCLEASE S, SULFATE ION
Authors:Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M.
Deposit date:1992-02-19
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures.
Biochemistry, 31, 1992
2RNF
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BU of 2rnf by Molmil
X-RAY CRYSTAL STRUCTURE OF HUMAN RIBONUCLEASE 4 IN COMPLEX WITH D(UP)
Descriptor: 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, RIBONUCLEASE 4
Authors:Terzyan, S.S, Peracaula, R, De Llorens, R, Tsushima, Y, Yamada, H, Seno, M, Gomis-Ruth, F.X, Coll, M.
Deposit date:1998-11-03
Release date:1999-11-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity.
J.Mol.Biol., 285, 1999
2RAT
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BU of 2rat by Molmil
EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K
Descriptor: RIBONUCLEASE A
Authors:Tiltonjunior, R.F, Dewan, J.C, Petsko, G.A.
Deposit date:1991-08-13
Release date:1993-07-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
2W5G
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BU of 2w5g by Molmil
RNASE A-5'-ATP COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate- Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2W5I
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BU of 2w5i by Molmil
RNASE A-AP3A COMPLEX
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2W5K
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BU of 2w5k by Molmil
RNASE A-NADPH COMPLEX
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2W5M
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RNASE A-PYROPHOSPHATE ION COMPLEX
Descriptor: PYROPHOSPHATE 2-, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2W5L
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BU of 2w5l by Molmil
RNASE A-NADP COMPLEX
Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RIBONUCLEASE PANCREATIC
Authors:Chavali, G.B, Holloway, D.E, Baker, M.D, Acharya, K.R.
Deposit date:2008-12-10
Release date:2009-02-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of Naturally-Occurring 5'-Pyrophosphate-Linked Substituents on the Binding of Adenylic Inhibitors to Ribonuclease A: An X-Ray Crystallographic Study.
Biopolymers, 91, 2009
2VQ9
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BU of 2vq9 by Molmil
RNASE ZF-3E
Descriptor: CHLORIDE ION, RNASE 1
Authors:Kazakou, K, Holloway, D.E, Prior, S.H, Subramanian, V, Acharya, K.R.
Deposit date:2008-03-12
Release date:2008-06-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and Their Evolutionary Implications
J.Mol.Biol., 380, 2008
2XOI
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BU of 2xoi by Molmil
Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A
Descriptor: (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC
Authors:Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R.
Deposit date:2010-08-17
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A.
FEBS J., 278, 2011
2XOG
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BU of 2xog by Molmil
Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A
Descriptor: (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC
Authors:Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R.
Deposit date:2010-08-16
Release date:2011-01-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A.
FEBS J., 278, 2011
1O0F
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BU of 1o0f by Molmil
RNASE A in complex with 3',5'-ADP
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Ribonuclease pancreatic
Authors:Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M.
Deposit date:2003-02-21
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0M
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BU of 1o0m by Molmil
Ribonuclease A in complex with uridine-2'-phosphate
Descriptor: PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, Ribonuclease pancreatic
Authors:Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M.
Deposit date:2003-02-24
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0N
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BU of 1o0n by Molmil
Ribonuclease A in complex with uridine-3'-phosphate
Descriptor: 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic
Authors:Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M.
Deposit date:2003-02-24
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1N3Z
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BU of 1n3z by Molmil
Crystal structure of the [S-carboxyamidomethyl-Cys31, S-carboxyamidomethyl-Cys32] monomeric derivative of the bovine seminal ribonuclease in the liganded state
Descriptor: 3'-URIDINEMONOPHOSPHATE, ADENOSINE, Ribonuclease, ...
Authors:Sica, F, Di Fiore, A, Zagari, A, Mazzarella, L.
Deposit date:2002-10-30
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
Proteins, 52, 2003
1N1X
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BU of 1n1x by Molmil
Crystal Structure Analysis of the monomeric [S-carboxyamidomethyl-Cys31, S-carboxyamidomethyl-Cys32] Bovine seminal ribonuclease
Descriptor: Ribonuclease, seminal
Authors:Sica, F, Di Fiore, A, Zagari, A, Mazzarella, L.
Deposit date:2002-10-21
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
Proteins, 52, 2003
1OJ1
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BU of 1oj1 by Molmil
Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA)
Descriptor: CYTIDYL-2'-5'-PHOSPHO-GUANOSINE, RC-RNASE6 RIBONUCLEASE, SULFATE ION
Authors:Tsai, C.-J, Liu, J.-H, Liao, Y.-D, Chen, L.-y, Cheng, P.-T, Sun, Y.-J.
Deposit date:2003-06-28
Release date:2004-07-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana Catesbeiana of Two Crystal Structures Complexed with C(2,5 Cpg) and D(Apcpgpa)
To be Published
1PU3
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BU of 1pu3 by Molmil
The Solution NMR Structure and Dynamics of a Recombinant Onconase with Altered N-terminal and Met23 residues
Descriptor: P-30 protein
Authors:Gorbatyuk, V.Y, Tsai, C.K, Chang, C.F, Huang, T.H.
Deposit date:2003-06-24
Release date:2004-03-16
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Effect of N-terminal and Met23 Mutations on the Structure and Dynamics of Onconase
J.Biol.Chem., 279, 2004
1O0O
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BU of 1o0o by Molmil
Ribonuclease A in complex with adenosine-2',5'-diphosphate
Descriptor: ADENOSINE-2'-5'-DIPHOSPHATE, Ribonuclease pancreatic
Authors:Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M.
Deposit date:2003-02-24
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0H
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BU of 1o0h by Molmil
Ribonuclease A in complex with 5'-ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Ribonuclease pancreatic
Authors:Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M.
Deposit date:2003-02-21
Release date:2003-12-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1OJ8
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BU of 1oj8 by Molmil
Novel and retro Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with d(ApCpGpA) and (2',5'CpG)
Descriptor: 5'-D(*AP*CP*GP*AP)-3', RC-RNASE6 RIBONUCLEASE, SULFATE ION
Authors:Tsai, C.-J, Liu, J.-H, Liao, Y.-D, Chen, L.-Y, Cheng, P.-T, Sun, Y.-J.
Deposit date:2003-07-07
Release date:2004-07-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Retro and Novel Binding Modes in Cytotoxic Ribonucleases from Rana Catesbeiana of Two Crystal Structures Complexed with (2',5'Cpg) and D(Apcpgpa)
To be Published
1ONC
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BU of 1onc by Molmil
THE REFINED 1.7 ANGSTROMS X-RAY CRYSTALLOGRAPHIC STRUCTURE OF P-30, AN AMPHIBIAN RIBONUCLEASE WITH ANTI-TUMOR ACTIVITY
Descriptor: P-30 PROTEIN, SULFATE ION
Authors:Mosimann, S.C, Ardelt, W, James, M.N.G.
Deposit date:1993-08-30
Release date:1994-01-31
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Refined 1.7 A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity.
J.Mol.Biol., 236, 1994
1QHC
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BU of 1qhc by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-PHOSPHO-2'-DEOXYURIDINE-3'-PYROPHOSPHATE ADENOSINE-3'-PHOSPHATE
Descriptor: ADENYLATE-3'-PHOSPHATE-[[2'-DEOXY-URIDINE-5'-PHOSPHATE]-3'-PHOSPHATE], PROTEIN (RIBONUCLEASE A)
Authors:Leonidas, D.D, Acharya, K.R.
Deposit date:1999-05-12
Release date:1999-08-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor.
Biochemistry, 38, 1999
1QMT
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Recombinant Human Eosinophil Cationic Protein
Descriptor: EOSINOPHIL CATIONIC PROTEIN
Authors:Boix, E, Leonidas, D.D, Acharya, K.R.
Deposit date:1999-10-06
Release date:2000-02-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of Eosinophil Cationic Protein at 2.4 A Resolution
Biochemistry, 38, 1999

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