PDB: 223790 resultsInfo pagesStatus searchChemie searchBIRD

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8PO3	Discovery and Optimisation of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. Compound 18 bound to EGFR[V948R] Descriptor: 2-methyl-5-[[3-[1-[(3~{S})-1-propanoylpyrrolidin-3-yl]-4-pyridin-4-yl-pyrazol-3-yl]phenoxy]methyl]-3~{H}-isoindol-1-one, Epidermal growth factor receptor Authors: Hargreaves, D. Deposit date: 2023-07-03 Release date: 2024-06-05 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Discovery and Optimization of Potent, Efficacious and Selective Inhibitors Targeting EGFR Exon20 Insertion Mutations. J.Med.Chem., 67, 2024
8R8F	Ensemble-refined carboxymyoglobin photolysis power titration, 6 mJ/cm2 Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-29 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R90	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 604 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9H	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 661 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RA3	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 462 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R94	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 1001 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9L	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 1036 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RAA	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 1023 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R8Z	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 471 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9F	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 537 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R8I	Ensemble-refined carboxymyoglobin photolysis power titration, 56 mJ/cm2 Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-29 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RA1	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 312 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R95	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 1401 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RAD	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 1235 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9N	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 1224 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RA9	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 907 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R8W	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 254 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9E	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 469 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9P	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 1297 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RAB	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 1112 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R8H	Ensemble-refined carboxymyoglobin photolysis power titration, 31 mJ/cm2 Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-29 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R93	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 847 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R9K	Multicopy-refined carboxymyoglobin photolysis time series at 23 mJ/cm2 laser fluence, 922 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8RA4	Multicopy-refined carboxymyoglobin photolysis time series at 101 mJ/cm2 laser fluence, 527 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-12-01 Release date: 2024-01-31 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024
8R8X	Multicopy-refined carboxymyoglobin photolysis time series at 5 mJ/cm2 laser fluence, 327 fs time delay Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Barends, T, Schlichting, I. Deposit date: 2023-11-30 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Influence of pump laser fluence on ultrafast myoglobin structural dynamics. Nature, 626, 2024

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