4F8H
 
 | | X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel | | Descriptor: | (R)-ketamine, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Proton-gated ion channel, ... | | Authors: | Pan, J.J, Chen, Q, Willenbring, D, Kong, X.P, Cohen, A, Xu, Y, Tang, P. | | Deposit date: | 2012-05-17 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine.
Structure, 20, 2012
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7LHE
 | | Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state | | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION | | Authors: | Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. | | Deposit date: | 2021-01-22 | | Release date: | 2021-06-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
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7LHF
 | | Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state | | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION | | Authors: | Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. | | Deposit date: | 2021-01-22 | | Release date: | 2021-06-02 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
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3P50
 | | Structure of propofol bound to a pentameric ligand-gated ion channel, GLIC | | Descriptor: | 2,6-BIS(1-METHYLETHYL)PHENOL, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. | | Deposit date: | 2010-10-07 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Nature, 469, 2011
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3P4W
 | | Structure of desflurane bound to a pentameric ligand-gated ion channel, GLIC | | Descriptor: | (2S)-2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | Authors: | Nury, H, Van Renterghem, C, Weng, Y, Tran, A, Baaden, M, Dufresne, V, Changeux, J.P, Sonner, J.M, Delarue, M, Corringer, P.J. | | Deposit date: | 2010-10-07 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel
Nature, 469, 2011
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7YP7
 | | apo-ADGRG2 coupled to Gs | | Descriptor: | Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Liu, Z.M, Bu, R.Q, Xue, C.Y, Guo, S.C, Yuan, D.P, Xiao, P, Sun, J.P. | | Deposit date: | 2022-08-02 | | Release date: | 2022-08-24 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | apo-ADGRG2 coupled to Gs
Nat.Chem.Biol., 2022
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7YDJ
 | | Cryo EM structure of CD97/miniG12 complex | | Descriptor: | Adhesion G protein-coupled receptor E5 subunit beta, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | He, Y, Wang, N. | | Deposit date: | 2022-07-04 | | Release date: | 2023-07-12 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Cryo EM structure of CD97/miniG12 complex
To Be Published
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2YKS
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1HAF
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1HAE
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1PZ8
 | | Modulation of agrin function by alternative splicing and Ca2+ binding | | Descriptor: | Agrin, CALCIUM ION | | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | | Deposit date: | 2003-07-10 | | Release date: | 2004-04-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding.
STRUCTURE, 12, 2004
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1PZ7
 | | Modulation of agrin function by alternative splicing and Ca2+ binding | | Descriptor: | Agrin, CALCIUM ION | | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | | Deposit date: | 2003-07-10 | | Release date: | 2004-04-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.421 Å) | | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding.
STRUCTURE, 12, 2004
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1Q56
 | | NMR structure of the B0 isoform of the agrin G3 domain in its Ca2+ bound state | | Descriptor: | Agrin | | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | | Deposit date: | 2003-08-06 | | Release date: | 2004-04-13 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding
Structure, 12, 2004
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1PZ9
 | | Modulation of agrin function by alternative splicing and Ca2+ binding | | Descriptor: | Agrin | | Authors: | Stetefeld, J, Alexandrescu, A.T, Maciejewski, M.W, Jenny, M, Rathgeb-Szabo, K, Schulthess, T, Landwehr, R, Frank, S, Ruegg, M.A, Kammerer, R.A. | | Deposit date: | 2003-07-10 | | Release date: | 2004-04-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Modulation of agrin function by alternative splicing and Ca2+ binding.
STRUCTURE, 12, 2004
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2AOW
 | | Histamine Methyltransferase (Natural Variant I105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine | | Descriptor: | Histamine N-methyltransferase, TACRINE | | Authors: | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | | Deposit date: | 2005-08-14 | | Release date: | 2005-09-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
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2AOX
 | | Histamine Methyltransferase (Primary Variant T105) Complexed with the Acetylcholinesterase Inhibitor and Altzheimer's Disease Drug Tacrine | | Descriptor: | Histamine N-methyltransferase, TACRINE | | Authors: | Horton, J.R, Sawada, K, Nishibori, M, Cheng, X. | | Deposit date: | 2005-08-14 | | Release date: | 2005-09-13 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.12 Å) | | Cite: | Structural basis for inhibition of histamine N-methyltransferase by diverse drugs
J.Mol.Biol., 353, 2005
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6PNW
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7SQ2
 | | Reprocessed and refined structure of Phospholipase C-beta and Gq signaling complex | | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, ACETATE ION, CALCIUM ION, ... | | Authors: | Endo-Streeter, S.T, Sondek, J, Harden, T.K. | | Deposit date: | 2021-11-04 | | Release date: | 2021-11-17 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Kinetic Scaffolding Mediated by a Phospholipase C-{beta} and Gq Signaling Complex
Science, 330, 2010
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1QKD
 | | ERABUTOXIN | | Descriptor: | ERABUTOXIN A | | Authors: | Nastopoulos, V, Kanellopoulos, P.N, Tsernoglou, D. | | Deposit date: | 1998-01-16 | | Release date: | 1999-02-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Structure of dimeric and monomeric erabutoxin a refined at 1.5 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
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1QKE
 | | ERABUTOXIN | | Descriptor: | ERABUTOXIN A, SULFATE ION | | Authors: | Nastopoulos, V, Kanellopoulos, P.N, Tsernoglou, D. | | Deposit date: | 1998-01-16 | | Release date: | 1999-02-16 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of dimeric and monomeric erabutoxin a refined at 1.5 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
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7SJL
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8IU2
 | | Cryo-EM structure of Long-wave-sensitive opsin 1 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Peng, Q, Cheng, X.Y, Li, J, Lu, Q.Y, Li, Y.Y, Zhang, J. | | Deposit date: | 2023-03-23 | | Release date: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Cryo-EM structure of Long-wave-sensitive opsin 1
To Be Published
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6EBX
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6CBV
 | | Crystal structure of BRIL bound to an affinity matured synthetic antibody. | | Descriptor: | BRIL, FORMIC ACID, GLYCEROL, ... | | Authors: | Mukherjee, S, Skrobek, B, Kossiakoff, A.A. | | Deposit date: | 2018-02-05 | | Release date: | 2019-02-06 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.872 Å) | | Cite: | Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
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1ERA
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