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5UWP
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Crystal Structure of mDia2 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5SZJ
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BU of 5szj by Molmil
Structure of human Rab10 in complex with the bMERB domain of Mical-cL
Descriptor: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, MICAL C-terminal-like protein, ...
Authors:Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Mueller, M.P, Gazdag, E.M.
Deposit date:2016-08-14
Release date:2016-08-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
5SZK
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BU of 5szk by Molmil
Structure of human N-terminally engineered Rab1b in complex with the bMERB domain of Mical-cL
Descriptor: MAGNESIUM ION, MICAL C-terminal-like protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Rai, A, Oprisko, A, Campos, J, Fu, Y, Friese, T, Itzen, A, Goody, R.S, Gazdag, E.M, Mueller, M.P.
Deposit date:2016-08-14
Release date:2016-08-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:bMERB domains are bivalent Rab8 family effectors evolved by gene duplication.
Elife, 5, 2016
5UWI
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BU of 5uwi by Molmil
Crystal Structure of HDAC5 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.143 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWU
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BU of 5uwu by Molmil
Crystal Structure of SMAD4 NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: CHLORIDE ION, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWW
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BU of 5uww by Molmil
Crystal Structure of DEAF1 Peptide in complex with CRM1 K579A mutant-Ran-RanBP1
Descriptor: Deformed epidermal autoregulatory factor 1 homolog, Exportin-1, GLYCEROL, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWJ
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BU of 5uwj by Molmil
Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1
Descriptor: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
Authors:Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-02-21
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.221 Å)
Cite:Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
7CND
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BU of 7cnd by Molmil
NCI-1 in complex with CRM1-Ran-RanBP1
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, CRM1 isoform 1, ...
Authors:Sun, Q, Lei, Y.
Deposit date:2020-07-31
Release date:2021-06-09
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Guided Design of the First Noncovalent Small-Molecule Inhibitor of CRM1.
J.Med.Chem., 64, 2021
7E8T
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BU of 7e8t by Molmil
Monomer of Ypt32-TRAPPII
Descriptor: GTP-binding protein YPT32/YPT11, TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, ...
Authors:Mi, C.C, Sui, S.F.
Deposit date:2021-03-02
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32.
Sci Adv, 8, 2022
7EA3
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BU of 7ea3 by Molmil
Intact Ypt32-TRAPPII (dimer).
Descriptor: GTP-binding protein YPT32/YPT11, TRAPP-associated protein TCA17, Trafficking protein particle complex II-specific subunit 120, ...
Authors:Mi, C.C, Sui, S.F.
Deposit date:2021-03-06
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.31 Å)
Cite:Structural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32.
Sci Adv, 8, 2022
7DBG
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BU of 7dbg by Molmil
Yeast CRM1e (apo) in complex with Ran-RanBP1
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, CRM1 isoform 1, ...
Authors:Sun, Q, Lei, Y.
Deposit date:2020-10-20
Release date:2021-09-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Novel Mechanistic Observations and NES-Binding Groove Features Revealed by the CRM1 Inhibitors Plumbagin and Oridonin.
J.Nat.Prod., 84, 2021
7G80
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BU of 7g80 by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1041785508
Descriptor: 5-(1,3-thiazol-2-yl)-1H-1,2,4-triazole, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.671 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G84
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BU of 7g84 by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1102357527
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N-[(3R)-6-oxopiperidin-3-yl]-1,3-thiazole-4-carboxamide, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.811 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G86
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BU of 7g86 by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1137725943
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N-[(1H-indol-4-yl)methyl]ethanamine, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G88
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BU of 7g88 by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1148747945
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N-(3-methylpyridin-4-yl)acetamide, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.869 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8H
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BU of 7g8h by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1198180782
Descriptor: 5-methoxy-1H-pyrrolo[3,2-b]pyridine, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8I
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BU of 7g8i by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1198316457
Descriptor: 4,4-difluorocyclohexane-1-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.468 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8B
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BU of 7g8b by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z100643660
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N,1-dimethyl-1H-indole-3-carboxamide, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8K
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BU of 7g8k by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1217131798
Descriptor: (3M)-3-(2-methyl-1H-imidazol-1-yl)pyridine, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.491 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8E
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BU of 7g8e by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z104479710
Descriptor: 1-(1H-benzimidazol-2-yl)methanamine, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G90
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BU of 7g90 by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1509195674
Descriptor: 4-[(3S)-piperidin-3-yl]-1H-indole, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.911 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8P
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BU of 7g8p by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1269184613
Descriptor: 1,3-benzothiazole-6-sulfonamide, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.209 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G93
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ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1565771450
Descriptor: DIMETHYL SULFOXIDE, FORMIC ACID, N-(8-methyl-1,2,3,4-tetrahydroquinolin-5-yl)acetamide, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.693 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G8S
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BU of 7g8s by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1270393711
Descriptor: 5-(methoxymethyl)-1,2-oxazole-3-carboxamide, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published
7G81
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BU of 7g81 by Molmil
ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z104474512
Descriptor: 1-(2-ethoxyphenyl)piperazine, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:Bradshaw, W.J, Katis, V.L, Bountra, C, von Delft, F, Brennan, P.E.
Deposit date:2023-06-22
Release date:2023-07-12
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:ARHGEF2 PanDDA analysis group deposition
To Be Published

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