PDB: 222415 resultsInfo pagesStatus searchChemie searchBIRD

---

7LNT	Ternary complex of the Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus bound to benzyl monophosphate and ATP Descriptor: (phenylmethyl) dihydrogen phosphate, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... Authors: Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R. Deposit date: 2021-02-08 Release date: 2021-12-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
7LES	Acanthamoeba castellanii CYP51 (AcCYP51)-Imidazole complex Descriptor: DI(HYDROXYETHYL)ETHER, FORMIC ACID, IMIDAZOLE, ... Authors: Sharma, V, Podust, L.M. Deposit date: 2021-01-15 Release date: 2021-12-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Homodimerization Counteracts the Detrimental Effect of Nitrogenous Heme Ligands on the Enzymatic Activity of Acanthamoeba castellanii CYP51. Biochemistry, 61, 2022
3USQ	Structure of D159S/Y194F glycogenin mutant truncated at residue 270 Descriptor: CHLORIDE ION, GLYCEROL, Glycogenin-1 Authors: Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A. Deposit date: 2011-11-23 Release date: 2011-12-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Mechanisms of monomeric and dimeric glycogenin autoglucosylation. J.Biol.Chem., 287, 2012
7LNV	Apo Structure of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus Descriptor: GLYCEROL, Isopentenyl phosphate kinase, MALONATE ION Authors: Thomas, L.M, Singh, S, Scull, E.M, Bourne, C.R. Deposit date: 2021-02-08 Release date: 2021-12-29 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus . Acs Chem.Biol., 17, 2022
7LUH	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment bromophenoxy propanamide Descriptor: (2~{R})-2-(4-bromanylphenoxy)propanamide, Thiol:disulfide interchange protein Authors: Petit, G.A, Martin, J.L, McMahon, R.M. Deposit date: 2021-02-22 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LUJ	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment 4-methoxy-N-phenylbenzenesulfonamide Descriptor: 4-methoxy-~{N}-phenyl-benzenesulfonamide, SULFATE ION, Thiol:disulfide interchange protein Authors: Petit, G.A, Martin, J.L, McMahon, R.M. Deposit date: 2021-02-22 Release date: 2022-01-05 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LL4	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-114. Descriptor: Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[3-fluoro-4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-02-03 Release date: 2022-01-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.31 Å) Cite: High-resolution crystal structure of human Janus Kinase 2 kinase domain (JH1) bound to PN5-114. To Be Published
7LAT	Campylobacter jejuni keto-acid reductoisomerase in complex with Mg2+ Descriptor: Ketol-acid reductoisomerase, MAGNESIUM ION Authors: Guddat, L.W. Deposit date: 2021-01-06 Release date: 2022-01-12 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Mapping of the Reaction Trajectory catalyzed by Class I Ketol-Acid Reductoisomerase Acs Catalysis, 2024
4OU3	Crystal structure of porcine aminopeptidase N complexed with CNGRCG tumor-homing peptide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ... Authors: Liu, C, Yang, Y, Chen, L, Lin, Y.-L, Li, F. Deposit date: 2014-02-14 Release date: 2014-11-05 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy. J.Biol.Chem., 289, 2014
7LL5	High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. Descriptor: 1,2-ETHANEDIOL, Tyrosine-protein kinase JAK2, {1-(ethylsulfonyl)-3-[4-(2-{[4-(1-methylpiperidin-4-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile Authors: Karim, M.R, Schonbrunn, E. Deposit date: 2021-02-03 Release date: 2022-01-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.5 Å) Cite: High-resolution crystal structure of human JAK2 kinase domain (JH1) bound to PN5-150. To Be Published
7LSQ	The Crystal Structure of Q108K:K40E:T53A:R58W:Q38F:Q4F:Y19W Mutant of HCRBPII Bound with LizFluor Chromophore Showing Excited State Intermolecular Proton Transfer Descriptor: 4-{5-[(2E)-but-2-en-2-yl]thiophen-2-yl}-N,N-dimethylaniline, ACETATE ION, Retinol-binding protein 2 Authors: Ghanbarpour, A, Geiger, J. Deposit date: 2021-02-18 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.67130542 Å) Cite: Design of Large Stokes Shift Fluorescent Proteins Based on Excited State Proton Transfer of an Engineered Photobase. J.Am.Chem.Soc., 143, 2021
7M1E	Structural and functional studies about scorpine showed the presence of blocking channel and cytolytic activities as well as two different structural domains Descriptor: Scorpine Authors: del Rio, J.F, Lopez, A.E, Titaux, G. Deposit date: 2021-03-12 Release date: 2022-01-19 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural and functional studies of scorpine: A channel blocker and cytolytic peptide. Toxicon, 222, 2022
7LAF	15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor Descriptor: 3-{[(4-methylphenyl)methyl]sulfanyl}-1-phenyl-1H-1,2,4-triazole, MANGANESE (II) ION, Polyunsaturated fatty acid lipoxygenase ALOX15B Authors: Newcomer, M.E, Gilbert, N.C, Neau, D.B. Deposit date: 2021-01-06 Release date: 2022-01-19 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Kinetic and structural investigations of novel inhibitors of human epithelial 15-lipoxygenase-2. Bioorg.Med.Chem., 46, 2021
7L91	Structure of Metallo Beta-Lactamase L1 in a Complex with Hydrolyzed Moxalactam Determined by Pink-Beam Serial Crystallography Descriptor: (2R)-2-[(R)-carboxy{[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino}methoxymethyl]-5-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-3,6-dihydro-2H-1,3-oxazine-4-carboxylic acid, Putative metallo-beta-lactamase l1 (Beta-lactamase type ii) (Ec 3.5.2.6) (Penicillinase), ZINC ION Authors: Wilamowski, M, Kim, Y, Sherrell, D.A, Lavens, A, Henning, R, Maltseva, N, Endres, M, Babnigg, G, Vukica, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2021-01-01 Release date: 2022-02-09 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase. Nat Commun, 13, 2022
7LVE	Jug r 2 Leader Sequence Residues 117-161 Descriptor: Vicilin Jug r 2.0101 Authors: Mueller, G.A, Foo, A.C.Y, DeRose, E.F. Deposit date: 2021-02-25 Release date: 2022-02-02 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure, Immunogenicity, and IgE Cross-Reactivity among Walnut and Peanut Vicilin-Buried Peptides. J.Agric.Food Chem., 70, 2022
7LH6	The structure of Bacteroides plebeius L-galactose dehydrogenase Descriptor: L-galactose dehydrogenase Authors: Robb, C.S, Pluvinage, B, Vickers, C, Boraston, A.B. Deposit date: 2021-01-21 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Metabolism of a hybrid algal galactan by members of the human gut microbiome. Nat.Chem.Biol., 18, 2022
4FQR	Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing antibody C05, ... Authors: Ekiert, D.C, Wilson, I.A. Deposit date: 2012-06-25 Release date: 2012-09-19 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (4.1 Å) Cite: Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489, 2012
5JY7	Complex of Mycobacterium smegmatis trehalose synthase with maltokinase Descriptor: CALCIUM ION, Maltokinase, Trehalose synthase/amylase TreS Authors: Futterer, K, Kermani, A.A, Besra, G.S. Deposit date: 2016-05-13 Release date: 2017-05-24 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Crystal structure of the TreS-Pep2 complex, initiating alpha-glucan synthesis in the GlgE pathway of mycobacteria. J.Biol.Chem., 2019
7LJP	Structure of Thermotoga maritima SmpB Descriptor: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ... Authors: Chan, C.W, Mondragon, A. Deposit date: 2021-01-29 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of Thermotoga maritima SmpB reveals its C-terminal tail domain in a helical conformation mimicking that of a ribosome-bound state To Be Published
7LFF	Crystal structure of the Candida albicans kinesin-8 motor domain Descriptor: ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION Authors: Allingham, J.S, Hunter, B. Deposit date: 2021-01-16 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7LGG	Asymmetric unit for phage Qbeta oblate particle Descriptor: Capsid protein Authors: Chang, J.Y, Zhang, J. Deposit date: 2021-01-20 Release date: 2022-01-26 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (6.2 Å) Cite: Structural Assembly of Q beta Virion and Its Diverse Forms of Virus-like Particles. Viruses, 14, 2022
7LGH	Asymmetric unit for phage Qbeta small prolate particle Descriptor: Capsid protein Authors: Chang, J.Y, Zhang, J. Deposit date: 2021-01-20 Release date: 2022-01-26 Last modified: 2022-03-09 Method: ELECTRON MICROSCOPY (8.9 Å) Cite: Structural Assembly of Q beta Virion and Its Diverse Forms of Virus-like Particles. Viruses, 14, 2022
7LHA	Structure of the Exo-L-galactose-6-sulfatase BuS1_11 from Bacteroides uniformis Descriptor: CALCIUM ION, Exo-L-galactose-6-sulfatase, NICKEL (II) ION Authors: Robb, C.S, Boraston, A.B. Deposit date: 2021-01-21 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Metabolism of a hybrid algal galactan by members of the human gut microbiome. Nat.Chem.Biol., 18, 2022
7LNP	Structure of the exo-alpha-L-galactosidase BpGH29 (D264N mutant) from Bacteroides plebeius in complex with paranitrophenyl-alpha-L-galactopyranoside Descriptor: CALCIUM ION, CHLORIDE ION, Exo-alpha-L-galactosidase, ... Authors: Boraston, A.B, Robb, C.S. Deposit date: 2021-02-08 Release date: 2022-02-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Metabolism of a hybrid algal galactan by members of the human gut microbiome. Nat.Chem.Biol., 18, 2022
7LIH	CryoEM structure of Mayaro virus icosahedral subunit Descriptor: Capsid protein, E1 protein, E2 protein Authors: Chmielewski, D, Kaelber, J.T, Jin, J, Weaver, S, Auguste, A.J, Chiu, W. Deposit date: 2021-01-27 Release date: 2022-02-09 Last modified: 2023-11-01 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Near-atomic resolution Cryo-EM structure of Mayaro virus identifies key structural determinants of alphavirus particle formation To Be Published

<312313314315316317318319320321322323324325326327>