PDB: 69 件ウェブページステータス検索Chemie searchBIRD

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3PAW	Low resolution X-ray crystal structure of Yeast Rnr1p with dATP bound in the A-site 分子名称: Ribonucleoside-diphosphate reductase large chain 1 著者 Fairman, J.W, Wijerathna, S.R, Dealwis, C.G. 登録日 2010-10-19 公開日 2011-02-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (6.61 Å) 主引用文献 Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
3R1R	RIBONUCLEOTIDE REDUCTASE R1 PROTEIN WITH AMPPNP OCCUPYING THE ACTIVITY SITE FROM ESCHERICHIA COLI 分子名称: ADENOSINE-5'-TRIPHOSPHATE, RIBONUCLEOTIDE REDUCTASE R1 PROTEIN, RIBONUCLEOTIDE REDUCTASE R2 PROTEIN 著者 Eriksson, M, Eklund, H. 登録日 1997-07-21 公開日 1998-01-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Binding of allosteric effectors to ribonucleotide reductase protein R1: reduction of active-site cysteines promotes substrate binding. Structure, 5, 1997
3RSR	Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase 分子名称: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 著者 Wan, Q, Mohammed, F, Jha, S, Motea, E, Berdis, A, Dealwis, C.G. 登録日 2011-05-02 公開日 2012-11-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase. Mol.Cancer Ther., 11, 2012
3S8B	Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP 分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. 登録日 2011-05-27 公開日 2012-04-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S8A	Structure of Yeast Ribonucleotide Reductase R293A with dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. 登録日 2011-05-27 公開日 2012-04-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S87	Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. 登録日 2011-05-27 公開日 2012-04-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3S8C	Structure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDP 分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. 登録日 2011-05-27 公開日 2012-04-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase To be Published
3TB9	Structure of Yeast Ribonucleotide Reductase 1 Q288A with AMPPNP and CDP 分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D. 登録日 2011-08-05 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
3TBA	Structure of Yeast Ribonucleotide Reductase 1 Q288A with dGTP and ADP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C. 登録日 2011-08-05 公開日 2012-04-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase. J.Mol.Biol., 419, 2012
2XAW	Ribonucleotide reductase Y730NO2Y and Y731F modified R1 subunit of E. coli 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Yokoyama, K, Uhlin, U, Stubbe, J. 登録日 2010-03-31 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAX	Ribonucleotide reductase Y730NO2Y and Y731A modified R1 subunit of E. coli 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Yokoyama, K, Uhlin, U, Stubbe, J. 登録日 2010-04-01 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAZ	Ribonucleotide reductase Y730NO2Y and C439S modified R1 subunit of E. coli 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Yokoyama, K, Uhlin, U, Stubbe, J. 登録日 2010-04-01 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAV	Ribonucleotide reductase Y731NO2Y and Y730F modified R1 subunit of E. coli 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Yokoyama, K, Uhlin, U, Stubbe, J. 登録日 2010-03-31 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAP	Ribonucleotide reductase Y731NO2Y modified R1 subunit of E. coli to 2. 1 A resolution 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Yokoyama, K, Uhlin, U, Stubbe, J. 登録日 2010-03-31 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XAY	Ribonucleotide reductase Y730NO2Y and C439A modified R1 subunit of E. coli 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Yokoyama, K, Uhlin, U, Stubbe, J. 登録日 2010-04-01 公開日 2010-04-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of Pk(A) Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase. J.Am.Chem.Soc., 132, 2010
2XO4	RIBONUCLEOTIDE REDUCTASE Y730NH2Y MODIFIED R1 SUBUNIT OF E. COLI 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J. 登録日 2010-08-09 公開日 2010-08-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases. J.Am.Chem.Soc., 133, 2011
2XO5	RIBONUCLEOTIDE REDUCTASE Y731NH2Y MODIFIED R1 SUBUNIT OF E. COLI 分子名称: RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT BETA 著者 Minnihan, E.C, Seyedsayamdost, M.R, Uhlin, U, Stubbe, J. 登録日 2010-08-09 公開日 2010-08-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Kinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine- Substituted Escherichia Coli Ribonucleotide Reductases. J.Am.Chem.Soc., 133, 2011
2ZLF	The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase 分子名称: FTLDADF, Ribonucleoside-diphosphate reductase large chain 1 著者 Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. 登録日 2008-04-09 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
2ZLG	The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase 分子名称: (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1 著者 Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. 登録日 2008-04-09 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008

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