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127L	THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1993-05-28 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993
130L	STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Pjura, P, Matthews, B.W. Deposit date: 1993-05-28 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent. Protein Sci., 2, 1993
131L	STRUCTURES OF RANDOMLY GENERATED MUTANTS OF T4 LYSOZYME SHOW THAT PROTEIN STABILITY CAN BE ENHANCED BY RELAXATION OF STRAIN AND BY IMPROVED HYDROGEN BONDING VIA BOUND SOLVENT Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Pjura, P, Matthews, B.W. Deposit date: 1993-05-28 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent. Protein Sci., 2, 1993
138L	RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Heinz, D.W, Matthews, B.W. Deposit date: 1993-09-01 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking. Protein Eng., 7, 1994
139L	RAPID CRYSTALLIZATION OF T4 LYSOZYME BY INTERMOLECULAR DISULFIDE CROSSLINKING Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Heinz, D.W, Matthews, B.W. Deposit date: 1993-09-01 Release date: 1994-01-31 Last modified: 2017-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking. Protein Eng., 7, 1994
137L	STRUCTURAL BASIS OF AMINO ACID ALPHA HELIX PROPENSITY Descriptor: T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1993-08-17 Release date: 1994-07-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural basis of amino acid alpha helix propensity. Science, 260, 1993
140L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
141L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
143L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
142L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
145L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
144L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
162L	CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1994-06-20 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995
183L	SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, INDENE, ... Authors: Morton, A, Matthews, B.W. Deposit date: 1995-04-19 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995
147L	ROLE OF BACKBONE FLEXIBILITY IN THE ACCOMMODATION OF VARIANTS THAT REPACK THE CORE OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E, Matthews, B.W. Deposit date: 1993-10-15 Release date: 1994-01-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme. Science, 262, 1993
197L	THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME Authors: Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. Deposit date: 1995-11-06 Release date: 1996-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
163L	CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1994-06-20 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995
182L	SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY Descriptor: 2-HYDROXYETHYL DISULFIDE, BENZOFURAN, CHLORIDE ION, ... Authors: Morton, A, Matthews, B.W. Deposit date: 1995-04-19 Release date: 1995-07-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995
104L	HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME Descriptor: T4 LYSOZYME Authors: Heinz, D.W, Matthews, B.W. Deposit date: 1992-09-29 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.8 Å) Cite: How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme. Nature, 361, 1993
103L	HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Heinz, D.W, Matthews, B.W. Deposit date: 1992-09-29 Release date: 1993-10-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme. Nature, 361, 1993
149L	CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME Descriptor: T4 LYSOZYME Authors: Wilson, K, Matthews, B.W. Deposit date: 1994-01-25 Release date: 1994-04-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Conservation of solvent-binding sites in 10 crystal forms of T4 lysozyme. Protein Sci., 3, 1994
155L	CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1994-06-20 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995
164L	CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1994-06-20 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995
192L	A HELIX INITIATION SIGNAL IN T4 LYSOZYME IDENTIFIED BY POLYALANINE MUTAGENESIS Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME Authors: Zhang, X.-J, Matthews, B.W. Deposit date: 1995-06-13 Release date: 1995-09-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A helix initiation signal in T4 lysozyme identified by polyalanine mutagenesis. Biophys.Chem., 101-102, 2002
156L	CONTROL OF ENZYME ACTIVITY BY AN ENGINEERED DISULFIDE BOND Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1994-06-20 Release date: 1994-08-31 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent. J.Mol.Biol., 246, 1995

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