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2M51
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BU of 2m51 by Molmil
NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1
Descriptor: Ras GTPase-activating protein 1
Authors:Dutta, S.K, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2013-02-12
Release date:2013-03-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1
To be Published
2P0D
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BU of 2p0d by Molmil
ArhGAP9 PH domain in complex with Ins(1,4,5)P3
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rho GTPase-activating protein 9
Authors:Ceccarelli, D.F.J, Blasutig, I, Goudreault, M, Ruston, J, Pawson, T, Sicheri, F.
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.811 Å)
Cite:Non-canonical Interaction of Phosphoinositides with Pleckstrin Homology Domains of Tiam1 and ArhGAP9.
J.Biol.Chem., 282, 2007
2EXF
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BU of 2exf by Molmil
Solution structure of the HIV-1 nucleocapsid (NCp7(12-55)) complexed with the DNA (-) Primer Binding Site
Descriptor: 5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*C)-3', Nucleocapsid protein* (NC*), ZINC ION
Authors:Bourbigot, S, Bouaziz, S, Morellet, N.
Deposit date:2005-11-08
Release date:2007-04-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.
J.Mol.Biol., 383, 2008
2OZM
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BU of 2ozm by Molmil
Crystal structure of RB69 gp43 in complex with DNA with 5-NITP opposite an abasic site analog
Descriptor: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ...
Authors:Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S.
Deposit date:2007-02-26
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Caught Bending the A-Rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide
Biochemistry, 46, 2007
2P27
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BU of 2p27 by Molmil
Crystal Structure of Human Pyridoxal Phosphate Phosphatase with Mg2+ at 1.9 A resolution
Descriptor: MAGNESIUM ION, Pyridoxal phosphate phosphatase
Authors:Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2007-03-07
Release date:2007-03-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
2MF8
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BU of 2mf8 by Molmil
HADDOCK model of MyT1 F4F5 - DNA complex
Descriptor: DNA (5'-D(*AP*CP*CP*GP*AP*AP*AP*GP*TP*TP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*AP*AP*CP*TP*TP*TP*CP*GP*GP*T)-3'), Myelin transcription factor 1, ...
Authors:Gamsjaeger, R, O'Connell, M.R, Cubeddu, L, Shepherd, N.E, Lowry, J.A, Kwan, A.H, Vandevenne, M, Swanton, M.K, Matthews, J.M, Mackay, J.P.
Deposit date:2013-10-08
Release date:2013-11-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers.
J.Biol.Chem., 288, 2013
2PA4
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BU of 2pa4 by Molmil
Crystal structure of UDP-glucose pyrophosphorylase from Corynebacteria glutamicum in complex with magnesium and UDP-glucose
Descriptor: MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE-GLUCOSE, UTP-GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE
Authors:Holden, H.M, Thoden, J.B.
Deposit date:2007-03-27
Release date:2007-04-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Active site geometry of glucose-1-phosphate uridylyltransferase.
Protein Sci., 16, 2007
2PTZ
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BU of 2ptz by Molmil
Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-out conformation
Descriptor: 1,2-ETHANEDIOL, Enolase, PHOSPHONOACETOHYDROXAMIC ACID, ...
Authors:Navarro, M.V.A.S, Rigden, D.J, Garratt, R.C, Dias, S.M.G.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics.
Febs J., 274, 2007
3R6C
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BU of 3r6c by Molmil
Anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis (complex with inhibitor ACS179)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 8-methoxyphenanthro[3,4-d][1,3]dioxole-5,6-dicarboxylic acid, Anthranilate phosphoribosyltransferase, ...
Authors:Castell, A, Short, F.L, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
Deposit date:2011-03-21
Release date:2012-09-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:The Substrate Capture Mechanism of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Provides a Mode for Inhibition.
Biochemistry, 52, 2013
3F9T
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BU of 3f9t by Molmil
Crystal structure of L-tyrosine decarboxylase MfnA (EC 4.1.1.25) (NP_247014.1) from METHANOCOCCUS JANNASCHII at 2.11 A resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, L-tyrosine decarboxylase MfnA, PYRIDOXAL-5'-PHOSPHATE
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2008-11-14
Release date:2008-11-25
Last modified:2023-02-01
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of L-tyrosine decarboxylase MfnA (EC 4.1.1.25) (NP_247014.1) from METHANOCOCCUS JANNASCHII at 2.11 A resolution
To be published
4GA9
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BU of 4ga9 by Molmil
Crystal Structure of Rat Galectin-1 in Complex with Lactose
Descriptor: Galectin-1, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose
Authors:Segev, O, Hirsch, J.A.
Deposit date:2012-07-25
Release date:2013-08-07
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Gal-1 structure analysis
to be published
1ETB
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BU of 1etb by Molmil
THE X-RAY CRYSTAL STRUCTURE REFINEMENTS OF NORMAL HUMAN TRANSTHYRETIN AND THE AMYLOIDOGENIC VAL 30-->MET VARIANT TO 1.7 ANGSTROMS RESOLUTION
Descriptor: 3,5,3',5'-TETRAIODO-L-THYRONINE, TRANSTHYRETIN
Authors:Braden, B.C, Steinrauf, L.K, Hamilton, J.A.
Deposit date:1993-05-12
Release date:1995-01-26
Last modified:2024-12-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution.
J.Biol.Chem., 268, 1993
2QWK
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BU of 2qwk by Molmil
THE X-RAY STRUCTURE OF A COMPLEX OF 5-N-ACETYL-5-AMINO-3-(1-ETHYLPROPOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID (GS4071) AND WILDTYPE TERN N9 INFLUENZA VIRUS NEURAMINIDASE
Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Varghese, J.N.
Deposit date:1998-04-07
Release date:1998-11-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.
Structure, 6, 1998
4OUE
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BU of 4oue by Molmil
Crystal structure of an a-L-Fucosidase GH29 from Bacteroides thetaiotaomicron (BT2192) in complex with IPTG
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, GLYCEROL, Putative lipoprotein
Authors:Lafite, P, Daniellou, R, Guillotin, L.
Deposit date:2014-02-16
Release date:2014-02-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Unraveling the Substrate Recognition Mechanism and Specificity of the Unusual Glycosyl Hydrolase Family 29 BT2192 from Bacteroides thetaiotaomicron.
Biochemistry, 53, 2014
1REM
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BU of 1rem by Molmil
HUMAN LYSOZYME WITH MAN-B1,4-GLCNAC COVALENTLY ATTACHED TO ASP53
Descriptor: LYSOZYME, NITRATE ION, R-1,2-PROPANEDIOL, ...
Authors:Muraki, M, Harata, K, Sugita, N, Sato, K.
Deposit date:1998-01-14
Release date:1998-07-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray structure of human lysozyme labelled with 2',3'-epoxypropyl beta-glycoside of man-beta1,4-GlcNAc. Structural change and recognition specificity at subsite B.
Acta Crystallogr.,Sect.D, 54, 1998
1ONW
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BU of 1onw by Molmil
Crystal structure of Isoaspartyl Dipeptidase from E. coli
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Isoaspartyl dipeptidase, ...
Authors:Thoden, J.B, Marti-Arbona, R, Raushel, F.M, Holden, H.M.
Deposit date:2003-03-02
Release date:2003-05-06
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:High Resolution X-ray Structure of Isoaspartyl Dipeptidase from Escherichia coli
Biochemistry, 42, 2003
4FW7
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BU of 4fw7 by Molmil
Crystal Structure of the LpxC in complex with N-[(2S,3R)-3-HYDROXY-1-(HYDROXYAMINO)-1-OXOBUTAN-2-YL]BIPHENYL-4-CARBOXAMIDE inhibitor
Descriptor: ACETATE ION, GLYCEROL, N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide, ...
Authors:Kang, Y.N, Stuckey, J.A.
Deposit date:2012-06-30
Release date:2013-05-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the LpxC
to be published
3NP9
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BU of 3np9 by Molmil
Glycogen phosphorylase complexed with 3-(beta-D-glucopyranosyl)-2-hydroxy-5-methoxy-chlorobenzene
Descriptor: (1S)-1,5-anhydro-1-(3-chloro-2-hydroxy-5-methoxyphenyl)-D-glucitol, Glycogen phosphorylase, muscle form
Authors:Alexacou, K.-M.
Deposit date:2010-06-28
Release date:2011-06-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Halogen-substituted (C-beta-D-glucopyranosyl)-hydroquinone regioisomers: synthesis, enzymatic evaluation and their binding to glycogen phosphorylase.
Bioorg.Med.Chem., 19, 2011
2KB5
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BU of 2kb5 by Molmil
Solution NMR Structure of Eosinophil Cationic Protein/RNase 3
Descriptor: Eosinophil cationic protein
Authors:Rico, M, Bruix, M, Laurents, D.V, Santoro, J, Jimenez, M, Boix, E, Moussaoui, M, Nogues, M.
Deposit date:2008-11-20
Release date:2009-06-23
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:The (1)H, (13)C, (15)N resonance assignment, solution structure, and residue level stability of eosinophil cationic protein/RNase 3 determined by NMR spectroscopy
Biopolymers, 91, 2009
1ET1
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BU of 1et1 by Molmil
CRYSTAL STRUCTURE OF HUMAN PARATHYROID HORMONE 1-34 AT 0.9 A RESOLUTION
Descriptor: PARATHYROID HORMONE, SODIUM ION
Authors:Jin, L, Briggs, S.L, Chandrasekhar, S, Chirgadze, N.Y, Clawson, D.K, Schevitz, R.W, Smiley, D.L, Tashjian, A.H, Zhang, F.
Deposit date:2000-04-12
Release date:2000-09-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Crystal structure of human parathyroid hormone 1-34 at 0.9-A resolution.
J.Biol.Chem., 275, 2000
3GXR
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The crystal structure of g-type lysozyme from Atlantic cod (Gadus morhua L.) in complex with NAG oligomers sheds new light on substrate binding and the catalytic mechanism. Structure with NAG to 1.7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Goose-type lysozyme 1
Authors:Helland, R, Larsen, R.L, Finstad, S, Kyomuhendo, P, Larsen, A.N.
Deposit date:2009-04-02
Release date:2009-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism.
Cell.Mol.Life Sci., 66, 2009
1R4W
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BU of 1r4w by Molmil
Crystal structure of Mitochondrial class kappa glutathione transferase
Descriptor: GLUTATHIONE, Glutathione S-transferase, mitochondrial
Authors:Ladner, J.E, Parsons, J.F, Rife, C.L, Gilliland, G.L, Armstrong, R.N.
Deposit date:2003-10-08
Release date:2004-02-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1
Biochemistry, 43, 2004
1R4P
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Shiga toxin type 2
Descriptor: 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, FORMIC ACID, ...
Authors:Fraser, M.E, Fujinaga, M, Cherney, M.M, Melton-Celsa, A.R, Twiddy, E.M, O'Brien, A.D, James, M.N.G.
Deposit date:2003-10-07
Release date:2004-05-11
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7.
J.Biol.Chem., 279, 2004
3O3U
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Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE)
Descriptor: Maltose-binding periplasmic protein, Advanced glycosylation end product-specific receptor, SULFATE ION, ...
Authors:Park, H, Boyington, J.C.
Deposit date:2010-07-26
Release date:2010-10-13
Last modified:2024-11-27
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:The 1.5 A crystal structure of human receptor for advanced glycation endproducts (RAGE) ectodomains reveals unique features determining ligand binding.
J.Biol.Chem., 285, 2010
2QQM
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Crystal Structure of the a2b1b2 Domains from Human Neuropilin-1
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2007-07-26
Release date:2007-11-20
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007

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