7TMR
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![BU of 7tmr by Molmil](/molmil-images/mine/7tmr) | V-ATPase from Saccharomyces cerevisiae, State 1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-type proton ATPase subunit C, ... | Authors: | Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L. | Deposit date: | 2022-01-19 | Release date: | 2022-04-13 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation. Nat.Struct.Mol.Biol., 29, 2022
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6TMI
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![BU of 6tmi by Molmil](/molmil-images/mine/6tmi) | Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, peripheral stalk model | Descriptor: | ATP synthase subunit alpha, ATPTG12, Oligomycin sensitivity conferring protein (OSCP), ... | Authors: | Muhleip, A, Kock Flygaard, R, Amunts, A. | Deposit date: | 2019-12-04 | Release date: | 2020-12-16 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria. Nat Commun, 12, 2021
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7U8O
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![BU of 7u8o by Molmil](/molmil-images/mine/7u8o) | Structure of porcine V-ATPase with mEAK7 and SidK, Rotary state 2 | Descriptor: | ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, Bacterial effector protein SidK, ... | Authors: | Tan, Y.Z, Keon, K.A. | Deposit date: | 2022-03-09 | Release date: | 2022-07-06 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7. Life Sci Alliance, 5, 2022
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8HHB
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![BU of 8hhb by Molmil](/molmil-images/mine/8hhb) | F1 domain of FoF1-ATPase from Bacillus PS3,step waiting,lowATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-11-16 | Release date: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Rotation mechanism of ATP synthases driven by ATP hydrolysis To Be Published
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6RDZ
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![BU of 6rdz by Molmil](/molmil-images/mine/6rdz) | Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2A, composite map | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | Authors: | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | Deposit date: | 2019-04-12 | Release date: | 2019-07-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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2XND
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![BU of 2xnd by Molmil](/molmil-images/mine/2xnd) | Crystal structure of bovine F1-c8 sub-complex of ATP Synthase | Descriptor: | ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT ALPHA, ... | Authors: | Watt, I.N, Montgomery, M.G, Runswick, M.J, Leslie, A.G.W, Walker, J.E. | Deposit date: | 2010-08-02 | Release date: | 2010-09-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Bioenergetic Cost of Making an Adenosine Triphosphate Molecule in Animal Mitochondria. Proc.Natl.Acad.Sci.USA, 107, 2010
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8F39
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![BU of 8f39 by Molmil](/molmil-images/mine/8f39) | Yeast ATP synthase in conformation-2, at pH 6 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... | Authors: | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | Deposit date: | 2022-11-09 | Release date: | 2024-02-07 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling. Nat.Struct.Mol.Biol., 31, 2024
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7JG7
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![BU of 7jg7 by Molmil](/molmil-images/mine/7jg7) | Cryo-EM structure of bedaquiline-free Mycobacterium smegmatis ATP synthase rotational state 3 (backbone model) | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ... | Authors: | Guo, H, Courbon, G.M, Rubinstein, J.L. | Deposit date: | 2020-07-18 | Release date: | 2020-08-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline. Nature, 589, 2021
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7Y5A
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![BU of 7y5a by Molmil](/molmil-images/mine/7y5a) | Cryo-EM structure of the Mycolicibacterium smegmatis F1-ATPase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Wong, C.F, Saw, W.-G, Grueber, G. | Deposit date: | 2022-06-16 | Release date: | 2022-11-23 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrob.Agents Chemother., 66, 2022
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6LY8
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![BU of 6ly8 by Molmil](/molmil-images/mine/6ly8) | V/A-ATPase from Thermus thermophilus, the soluble domain, including V1, d, two EG stalks, and N-terminal domain of a-subunit. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | Authors: | Kishikawa, J, Nakanishi, A, Furuta, A, Kato, T, Namba, K, Tamakoshi, M, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2020-02-13 | Release date: | 2020-09-09 | Last modified: | 2020-09-30 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Mechanical inhibition of isolated V o from V/A-ATPase for proton conductance. Elife, 9, 2020
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6RDU
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![BU of 6rdu by Molmil](/molmil-images/mine/6rdu) | Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1E, monomer-masked refinement | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... | Authors: | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | Deposit date: | 2019-04-12 | Release date: | 2019-07-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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8APC
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![BU of 8apc by Molmil](/molmil-images/mine/8apc) | rotational state 1c of the Trypanosoma brucei mitochondrial ATP synthase dimer | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | Authors: | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | Deposit date: | 2022-08-09 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases. Nat Commun, 13, 2022
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8APG
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![BU of 8apg by Molmil](/molmil-images/mine/8apg) | rotational state 2b of the Trypanosoma brucei mitochondrial ATP synthase dimer | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | Authors: | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | Deposit date: | 2022-08-09 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases. Nat Commun, 13, 2022
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3FKS
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![BU of 3fks by Molmil](/molmil-images/mine/3fks) | Yeast F1 ATPase in the absence of bound nucleotides | Descriptor: | ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ... | Authors: | Kabaleeswaran, V, Symersky, J, Shen, H, Walker, J.E, Leslie, A.G.W, Mueller, D.M. | Deposit date: | 2008-12-17 | Release date: | 2009-03-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.587 Å) | Cite: | Asymmetric structure of the yeast f1 ATPase in the absence of bound nucleotides. J.Biol.Chem., 284, 2009
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8DBP
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![BU of 8dbp by Molmil](/molmil-images/mine/8dbp) | E. coli ATP synthase imaged in 10mM MgATP State1 "half-up | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Sobti, M, Stewart, A.G. | Deposit date: | 2022-06-14 | Release date: | 2023-01-25 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Changes within the central stalk of E. coli F 1 F o ATP synthase observed after addition of ATP. Commun Biol, 6, 2023
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7TJV
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![BU of 7tjv by Molmil](/molmil-images/mine/7tjv) | |
7U4T
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![BU of 7u4t by Molmil](/molmil-images/mine/7u4t) | Human V-ATPase in state 2 with SidK and mEAK-7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ... | Authors: | Wang, L, Fu, T.M. | Deposit date: | 2022-03-01 | Release date: | 2022-08-24 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining. Proc.Natl.Acad.Sci.USA, 119, 2022
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6Q45
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![BU of 6q45 by Molmil](/molmil-images/mine/6q45) | F1-ATPase from Fusobacterium nucleatum | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Petri, J, Nakatani, Y, Montgomery, M.G, Ferguson, S.A, Aragao, D, Leslie, A.G.W, Heikal, A, Walker, J.E, Cook, G.M. | Deposit date: | 2018-12-05 | Release date: | 2019-07-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum. Open Biology, 9, 2019
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6RDY
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![BU of 6rdy by Molmil](/molmil-images/mine/6rdy) | Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1F, focussed refinement of F1 head and rotor | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. | Deposit date: | 2019-04-12 | Release date: | 2019-07-03 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
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7VAQ
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![BU of 7vaq by Molmil](/molmil-images/mine/7vaq) | V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state3-2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2021-08-30 | Release date: | 2022-07-13 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases. Nat Commun, 13, 2022
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7VB0
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![BU of 7vb0 by Molmil](/molmil-images/mine/7vb0) | V1EG domain of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2021-08-30 | Release date: | 2022-07-13 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases. Nat Commun, 13, 2022
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7NKK
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![BU of 7nkk by Molmil](/molmil-images/mine/7nkk) | Mycobacterium smegmatis ATP synthase rotor state 2 | Descriptor: | ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ... | Authors: | Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E. | Deposit date: | 2021-02-18 | Release date: | 2021-10-27 | Last modified: | 2021-11-24 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis. Proc.Natl.Acad.Sci.USA, 118, 2021
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8HH9
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![BU of 8hh9 by Molmil](/molmil-images/mine/8hh9) | F1 domain of FoF1-ATPase from Bacillus PS3, 90 degrees, low ATP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ... | Authors: | Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-11-16 | Release date: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Rotation mechanism of ATP synthases driven by ATP hydrolysis To Be Published
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6WM4
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![BU of 6wm4 by Molmil](/molmil-images/mine/6wm4) | Human V-ATPase in state 3 with SidK and ADP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ... | Authors: | Wang, L, Wu, H, Fu, T.M. | Deposit date: | 2020-04-20 | Release date: | 2020-11-11 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly. Mol.Cell, 80, 2020
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6R0W
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![BU of 6r0w by Molmil](/molmil-images/mine/6r0w) | |