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7TMR
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BU of 7tmr by Molmil
V-ATPase from Saccharomyces cerevisiae, State 1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, H(+)-transporting two-sector ATPase, V-type proton ATPase subunit C, ...
Authors:Vasanthakumar, T, Keon, K.A, Bueler, S.A, Jaskolka, M.C, Rubinstein, J.L.
Deposit date:2022-01-19
Release date:2022-04-13
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
Nat.Struct.Mol.Biol., 29, 2022
6TMI
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BU of 6tmi by Molmil
Cryo-EM structure of Toxoplasma gondii mitochondrial ATP synthase dimer, peripheral stalk model
Descriptor: ATP synthase subunit alpha, ATPTG12, Oligomycin sensitivity conferring protein (OSCP), ...
Authors:Muhleip, A, Kock Flygaard, R, Amunts, A.
Deposit date:2019-12-04
Release date:2020-12-16
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria.
Nat Commun, 12, 2021
7U8O
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BU of 7u8o by Molmil
Structure of porcine V-ATPase with mEAK7 and SidK, Rotary state 2
Descriptor: ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H+ transporting accessory protein 1, Bacterial effector protein SidK, ...
Authors:Tan, Y.Z, Keon, K.A.
Deposit date:2022-03-09
Release date:2022-07-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Life Sci Alliance, 5, 2022
8HHB
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BU of 8hhb by Molmil
F1 domain of FoF1-ATPase from Bacillus PS3,step waiting,lowATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-11-16
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
6RDZ
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BU of 6rdz by Molmil
Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2A, composite map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ...
Authors:Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W.
Deposit date:2019-04-12
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
2XND
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BU of 2xnd by Molmil
Crystal structure of bovine F1-c8 sub-complex of ATP Synthase
Descriptor: ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT ALPHA, ...
Authors:Watt, I.N, Montgomery, M.G, Runswick, M.J, Leslie, A.G.W, Walker, J.E.
Deposit date:2010-08-02
Release date:2010-09-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Bioenergetic Cost of Making an Adenosine Triphosphate Molecule in Animal Mitochondria.
Proc.Natl.Acad.Sci.USA, 107, 2010
8F39
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BU of 8f39 by Molmil
Yeast ATP synthase in conformation-2, at pH 6
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ...
Authors:Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
Deposit date:2022-11-09
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
7JG7
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BU of 7jg7 by Molmil
Cryo-EM structure of bedaquiline-free Mycobacterium smegmatis ATP synthase rotational state 3 (backbone model)
Descriptor: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ...
Authors:Guo, H, Courbon, G.M, Rubinstein, J.L.
Deposit date:2020-07-18
Release date:2020-08-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
Nature, 589, 2021
7Y5A
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BU of 7y5a by Molmil
Cryo-EM structure of the Mycolicibacterium smegmatis F1-ATPase
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Wong, C.F, Saw, W.-G, Grueber, G.
Deposit date:2022-06-16
Release date:2022-11-23
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
6LY8
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BU of 6ly8 by Molmil
V/A-ATPase from Thermus thermophilus, the soluble domain, including V1, d, two EG stalks, and N-terminal domain of a-subunit.
Descriptor: ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ...
Authors:Kishikawa, J, Nakanishi, A, Furuta, A, Kato, T, Namba, K, Tamakoshi, M, Mitsuoka, K, Yokoyama, K.
Deposit date:2020-02-13
Release date:2020-09-09
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mechanical inhibition of isolated V o from V/A-ATPase for proton conductance.
Elife, 9, 2020
6RDU
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BU of 6rdu by Molmil
Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1E, monomer-masked refinement
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ...
Authors:Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W.
Deposit date:2019-04-12
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
8APC
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BU of 8apc by Molmil
rotational state 1c of the Trypanosoma brucei mitochondrial ATP synthase dimer
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
Authors:Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
Deposit date:2022-08-09
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
8APG
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BU of 8apg by Molmil
rotational state 2b of the Trypanosoma brucei mitochondrial ATP synthase dimer
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ...
Authors:Muehleip, A, Gahura, O, Zikova, A, Amunts, A.
Deposit date:2022-08-09
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
3FKS
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BU of 3fks by Molmil
Yeast F1 ATPase in the absence of bound nucleotides
Descriptor: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ...
Authors:Kabaleeswaran, V, Symersky, J, Shen, H, Walker, J.E, Leslie, A.G.W, Mueller, D.M.
Deposit date:2008-12-17
Release date:2009-03-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.587 Å)
Cite:Asymmetric structure of the yeast f1 ATPase in the absence of bound nucleotides.
J.Biol.Chem., 284, 2009
8DBP
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BU of 8dbp by Molmil
E. coli ATP synthase imaged in 10mM MgATP State1 "half-up
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
Authors:Sobti, M, Stewart, A.G.
Deposit date:2022-06-14
Release date:2023-01-25
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Changes within the central stalk of E. coli F 1 F o ATP synthase observed after addition of ATP.
Commun Biol, 6, 2023
7TJV
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BU of 7tjv by Molmil
Yeast ATP synthase F1 region State 1catalytic(a) with 10 mM ATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ...
Authors:Guo, H, Rubinstein, J.L.
Deposit date:2022-01-17
Release date:2022-04-20
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of ATP synthase under strain during catalysis.
Nat Commun, 13, 2022
7U4T
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BU of 7u4t by Molmil
Human V-ATPase in state 2 with SidK and mEAK-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, MTOR-associated protein MEAK7, ...
Authors:Wang, L, Fu, T.M.
Deposit date:2022-03-01
Release date:2022-08-24
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Identification of mEAK-7 as a human V-ATPase regulator via cryo-EM data mining.
Proc.Natl.Acad.Sci.USA, 119, 2022
6Q45
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BU of 6q45 by Molmil
F1-ATPase from Fusobacterium nucleatum
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
Authors:Petri, J, Nakatani, Y, Montgomery, M.G, Ferguson, S.A, Aragao, D, Leslie, A.G.W, Heikal, A, Walker, J.E, Cook, G.M.
Deposit date:2018-12-05
Release date:2019-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of F1-ATPase from the obligate anaerobe Fusobacterium nucleatum.
Open Biology, 9, 2019
6RDY
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BU of 6rdy by Molmil
Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1F, focussed refinement of F1 head and rotor
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W.
Deposit date:2019-04-12
Release date:2019-07-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling.
Science, 364, 2019
7VAQ
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BU of 7vaq by Molmil
V1EG of V/A-ATPase from Thermus thermophilus, high ATP, state3-2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7VB0
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BU of 7vb0 by Molmil
V1EG domain of V/A-ATPase from Thermus thermophilus at saturated ATP-gamma-S condition, state3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Kishikawa, J, Nakanishi, A, Nakano, A, Saeki, S, Furuta, A, Kato, T, Mitsuoka, K, Yokoyama, K.
Deposit date:2021-08-30
Release date:2022-07-13
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural snapshots of V/A-ATPase reveal the rotary catalytic mechanism of rotary ATPases.
Nat Commun, 13, 2022
7NKK
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BU of 7nkk by Molmil
Mycobacterium smegmatis ATP synthase rotor state 2
Descriptor: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit alpha, ...
Authors:Montgomery, M.G, Petri, J, Spikes, T.E, Walker, J.E.
Deposit date:2021-02-18
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the ATP synthase from Mycobacterium smegmatis provides targets for treating tuberculosis.
Proc.Natl.Acad.Sci.USA, 118, 2021
8HH9
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BU of 8hh9 by Molmil
F1 domain of FoF1-ATPase from Bacillus PS3, 90 degrees, low ATP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase gamma chain, ...
Authors:Nakano, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K.
Deposit date:2022-11-16
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Rotation mechanism of ATP synthases driven by ATP hydrolysis
To Be Published
6WM4
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BU of 6wm4 by Molmil
Human V-ATPase in state 3 with SidK and ADP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ...
Authors:Wang, L, Wu, H, Fu, T.M.
Deposit date:2020-04-20
Release date:2020-11-11
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6R0W
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BU of 6r0w by Molmil
Thermus thermophilus V/A-type ATPase/synthase, rotational state 2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, V-type ATP synthase alpha chain, ...
Authors:Zhou, L, Sazanov, L.
Deposit date:2019-03-13
Release date:2019-08-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase.
Science, 365, 2019

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