8SYF
| Homology model of Acto-HMM complex in ADP-state. Chicken smooth muscle HMM and chicken pectoralis actin | Descriptor: | Actin, alpha skeletal muscle, Myosin light polypeptide 6, ... | Authors: | Hojjatian, A, Taylor, D.W, Daneshparvar, N, Trybus, K.M, Taylor, K.A. | Deposit date: | 2023-05-25 | Release date: | 2023-08-30 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (19 Å) | Cite: | Double-headed binding of myosin II to F-actin shows the effect of strain on head structure. J.Struct.Biol., 215, 2023
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8U95
| The structure of myosin heavy chain from Drosophila melanogaster flight muscle thick filaments | Descriptor: | Myosin heavy chain, isoform U | Authors: | Abbasi Yeganeh, F, Rastegarpouyani, H, Li, J, Taylor, K.A. | Deposit date: | 2023-09-18 | Release date: | 2023-10-18 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Structure of the Drosophila melanogaster Flight Muscle Myosin Filament at 4.7 angstrom Resolution Reveals New Details of Non-Myosin Proteins. Int J Mol Sci, 24, 2023
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8W41
| Cryo-EM structure of Myosin VI in the autoinhibited state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin-1, ... | Authors: | Niu, F, Wei, Z. | Deposit date: | 2023-08-23 | Release date: | 2024-02-21 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Autoinhibition and activation of myosin VI revealed by its cryo-EM structure. Nat Commun, 15, 2024
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9F6C
| Cardiac myosin motor domain in the pre-powerstroke state co-crystallized with the inhibitor aficamten | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-7, ... | Authors: | Robert-Paganin, J, Hartman, J.J, Morgan, B.P, Malik, F.I, Houdusse, A. | Deposit date: | 2024-05-01 | Release date: | 2024-09-04 | Last modified: | 2024-09-11 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy. Nat Cardiovasc Res, 3, 2024
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