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PDB: 2 results

7LAW
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BU of 7law by Molmil
crystal structure of GITR complex with GITR-L
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18
Authors:Longenecker, K.L, Rogers, B, Bigelow, L, Judge, R.A, Alvarez, H.
Deposit date:2021-01-07
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.752 Å)
Cite:An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy.
Nat Cancer, 3, 2022
7KHD
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BU of 7khd by Molmil
Human GITR-GITRL complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Tumor necrosis factor ligand superfamily member 18, Tumor necrosis factor receptor superfamily member 18
Authors:Wang, F, Chau, B, West, S.M, Strop, P.
Deposit date:2020-10-21
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.956102 Å)
Cite:Structures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions.
Nat Commun, 12, 2021

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