7D0E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d0e by Molmil](/molmil-images/mine/7d0e) | Crystal structure of FIP200 Claw/p-CCPG1 FIR2 | Descriptor: | 3-(2-hydroxyethyloxy)-2-[2-(2-hydroxyethyloxy)ethoxymethyl]-2-(2-hydroxyethyloxymethyl)propan-1-ol, Cell cycle progression protein 1 FIR2, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhou, Z.X, Pan, L.F. | Deposit date: | 2020-09-09 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12, 2021
|
|
5EP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ep6 by Molmil](/molmil-images/mine/5ep6) | The crystal structure of NAP1 in complex with TBK1 | Descriptor: | 5-azacytidine-induced protein 2, GLYCEROL, Serine/threonine-protein kinase TBK1 | Authors: | Li, F, Xie, X, Liu, J, Pan, L. | Deposit date: | 2015-11-11 | Release date: | 2016-09-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.451 Å) | Cite: | Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins. Nat Commun, 7, 2016
|
|
8YFM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yfm by Molmil](/molmil-images/mine/8yfm) | Crystal structure of FIP200 claw/TNIP1_FIR_pS122 | Descriptor: | GLYCEROL, RB1-inducible coiled-coil protein 1, SULFATE ION, ... | Authors: | Lv, M.Q, Wu, S.M. | Deposit date: | 2024-02-24 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for TNIP1 binding to FIP200 during mitophagy. J.Biol.Chem., 300, 2024
|
|
8YFL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yfl by Molmil](/molmil-images/mine/8yfl) | crystal structure of FIP200 claw/TNIP1_FIR_pS122pS123 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, RB1-inducible coiled-coil protein 1, ... | Authors: | Lv, M.Q, Wu, S.M. | Deposit date: | 2024-02-24 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for TNIP1 binding to FIP200 during mitophagy. J.Biol.Chem., 300, 2024
|
|
6DCE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dce by Molmil](/molmil-images/mine/6dce) | X-ray structure of FIP200 claw domain | Descriptor: | RB1-inducible coiled-coil protein 1, SULFATE ION | Authors: | Su, M.-Y, Hurley, J.H. | Deposit date: | 2018-05-05 | Release date: | 2019-03-06 | Last modified: | 2019-05-01 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates. Mol. Cell, 74, 2019
|
|
7CZG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7czg by Molmil](/molmil-images/mine/7czg) | Crystal structure of FIP200 Claw domain apo form | Descriptor: | DI(HYDROXYETHYL)ETHER, RB1-inducible coiled-coil protein 1 | Authors: | Zhou, Z.X, Pan, L.F. | Deposit date: | 2020-09-08 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12, 2021
|
|
8YFK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yfk by Molmil](/molmil-images/mine/8yfk) | Crystal structure of FIP200 claw/TNIP1_FIR_pS123 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, RB1-inducible coiled-coil protein 1, ... | Authors: | Lv, M.Q, Wu, S.M. | Deposit date: | 2024-02-24 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for TNIP1 binding to FIP200 during mitophagy. J.Biol.Chem., 300, 2024
|
|
7CZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7czm by Molmil](/molmil-images/mine/7czm) | Crystal structure of FIP200 Claw/p-OPtineurin LIR complex | Descriptor: | CHLORIDE ION, GLYCEROL, Optineurin LIR, ... | Authors: | Zhou, Z.X, Pan, L.F. | Deposit date: | 2020-09-09 | Release date: | 2021-03-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12, 2021
|
|
5Z7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z7l by Molmil](/molmil-images/mine/5z7l) | Crystal structure of NDP52 SKICH region in complex with NAP1 | Descriptor: | 5-azacytidine-induced protein 2, Calcium-binding and coiled-coil domain-containing protein 2, GLYCEROL | Authors: | Fu, T, Pan, L.F. | Deposit date: | 2018-01-29 | Release date: | 2019-01-02 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1 Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7EA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ea2 by Molmil](/molmil-images/mine/7ea2) | crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain | Descriptor: | 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Fu, T, Pan, L. | Deposit date: | 2021-03-06 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
|
|
8YFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yfn by Molmil](/molmil-images/mine/8yfn) | |
5Z7G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5z7g by Molmil](/molmil-images/mine/5z7g) | Crystal structure of TAX1BP1 SKICH region in complex with NAP1 | Descriptor: | 5-azacytidine-induced protein 2, GLYCEROL, Tax1-binding protein 1 | Authors: | Pan, L.F, Fu, T, Liu, J.P, Xie, X.Q, Wang, Y.L, Hu, S.C. | Deposit date: | 2018-01-28 | Release date: | 2019-01-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1 Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
8W6B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8w6b by Molmil](/molmil-images/mine/8w6b) | |
7EAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eaa by Molmil](/molmil-images/mine/7eaa) | crystal structure of NDP52 SKICH domain in complex with RB1CC1 coiled-coil domain | Descriptor: | Calcium-binding and coiled-coil domain-containing protein 2, RB1-inducible coiled-coil protein 1 | Authors: | Fu, T, Pan, L. | Deposit date: | 2021-03-06 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
|
|
7EA7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ea7 by Molmil](/molmil-images/mine/7ea7) | crystal structure of NAP1 LIR in complex with GABARAP | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif | Authors: | Fu, T, Pan, L. | Deposit date: | 2021-03-06 | Release date: | 2021-12-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52. Sci Adv, 7, 2021
|
|
6GMA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gma by Molmil](/molmil-images/mine/6gma) | |
8SOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8soi by Molmil](/molmil-images/mine/8soi) | Structure of human ULK1 complex core (2:1:1 stoichiometry) | Descriptor: | Autophagy-related protein 13, RB1-inducible coiled-coil protein 1, Serine/threonine-protein kinase ULK1 | Authors: | Chen, M, Hurley, J.H. | Deposit date: | 2023-04-28 | Release date: | 2023-06-21 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv, 2023
|
|
8SRM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8srm by Molmil](/molmil-images/mine/8srm) | |
8SQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8sqz by Molmil](/molmil-images/mine/8sqz) | |
9C82
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9c82 by Molmil](/molmil-images/mine/9c82) | Structure of human ULK1C:PI3KC3-C1 supercomplex | Descriptor: | Beclin 1-associated autophagy-related key regulator, Beclin-1, Phosphatidylinositol 3-kinase catalytic subunit type 3, ... | Authors: | Chen, M, Hurley, J.H. | Deposit date: | 2024-06-11 | Release date: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6.84 Å) | Cite: | Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv, 2023
|
|