1OC7
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![BU of 1oc7 by Molmil](/molmil-images/mine/1oc7) | D405N mutant of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS in complex with methyl-tetrathio-alpha-d-cellopentoside at 1.1 angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CELLOBIOHYDROLASE II, ... | Authors: | Varrot, A, Frandsen, T.P, Von Ossowski, I, Boyer, V, Driguez, H, Schulein, M, Davies, G.J. | Deposit date: | 2003-02-06 | Release date: | 2003-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.11 Å) | Cite: | Structural Basis for Ligand Binding and Processivity in Cellobiohydrolase Cel6A from Humicola Insolens Structure, 11, 2003
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4I5U
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![BU of 4i5u by Molmil](/molmil-images/mine/4i5u) | Crystal structure of a fungal chimeric cellobiohydrolase Cel6A | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Chimeric cel6A, ... | Authors: | Arnold, F.H, Wu, I. | Deposit date: | 2012-11-29 | Release date: | 2013-04-03 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures. Biotechnol.Bioeng., 110, 2013
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1OCJ
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![BU of 1ocj by Molmil](/molmil-images/mine/1ocj) | Mutant D416A of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS in complex with a THIOPENTASACCHARIDE at 1.3 angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CELLOBIOHYDROLASE II, ... | Authors: | Varrot, A, Frandsen, T.P, Von Ossowski, I, Boyer, V, Driguez, H, Schulein, M, Davies, G.J. | Deposit date: | 2003-02-07 | Release date: | 2003-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural Basis for Ligand Binding and Processivity in Cellobiohydrolase Cel6A from Humicola Insolens Structure, 11, 2003
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1OCN
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![BU of 1ocn by Molmil](/molmil-images/mine/1ocn) | Mutant D416A of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS in complex with a cellobio-derived isofagomine at 1.3 angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, CALCIUM ION, ... | Authors: | Varrot, A, Macdonald, J, Stick, R.V, Pell, G, Gilbert, H.J, Davies, G.J. | Deposit date: | 2003-02-09 | Release date: | 2003-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Distortion of a Cellobio-Derived Isofagomine Highlights the Potential Conformational Itinerary of Inverting Beta-Glucosidases Chem.Commun.(Camb.), 21, 2003
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4I5R
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![BU of 4i5r by Molmil](/molmil-images/mine/4i5r) | Crystal structure of a fungal chimeric cellobiohydrolase Cel6A | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Chimeric cel6A, ... | Authors: | Arnold, F.H, Wu, I. | Deposit date: | 2012-11-28 | Release date: | 2013-04-03 | Last modified: | 2017-08-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures. Biotechnol.Bioeng., 110, 2013
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1OC6
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![BU of 1oc6 by Molmil](/molmil-images/mine/1oc6) | structure native of the D405N mutant of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS at 1.5 angstrom resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CELLOBIOHYDROLASE II, ... | Authors: | Varrot, A, Frandsen, T.P, Von Ossowski, I, Boyer, V, Driguez, H, Schulein, M, Davies, G.J. | Deposit date: | 2003-02-06 | Release date: | 2003-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Basis for Ligand Binding and Processivity in Cellobiohydrolase Cel6A from Humicola Insolens Structure, 11, 2003
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1OC5
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![BU of 1oc5 by Molmil](/molmil-images/mine/1oc5) | D405N mutant of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS in complex with methyl-cellobiosyl-4-deoxy-4-thio-beta-D-cellobioside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE II, GLYCEROL, ... | Authors: | Varrot, A, Frandsen, T.P, Von Ossowski, I, Boyer, V, Driguez, H, Schulein, M, Davies, G.J. | Deposit date: | 2003-02-06 | Release date: | 2003-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for Ligand Binding and Processivity in Cellobiohydrolase Cel6A from Humicola Insolens Structure, 11, 2003
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2BVW
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![BU of 2bvw by Molmil](/molmil-images/mine/2bvw) | CELLOBIOHYDROLASE II (CEL6A) FROM HUMICOLA INSOLENS IN COMPLEX WITH GLUCOSE AND CELLOTETRAOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE II, GLYCEROL, ... | Authors: | Varrot, A, Davies, G.J, Schulein, M. | Deposit date: | 1999-02-18 | Release date: | 2000-02-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural changes of the active site tunnel of Humicola insolens cellobiohydrolase, Cel6A, upon oligosaccharide binding. Biochemistry, 38, 1999
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4AX7
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![BU of 4ax7 by Molmil](/molmil-images/mine/4ax7) | Hypocrea jecorina Cel6A D221A mutant soaked with 4-Methylumbelliferyl- beta-D-cellobioside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, EXOGLUCANASE 2, ... | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | Deposit date: | 2012-06-11 | Release date: | 2013-01-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases. FEBS J., 280, 2013
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4AU0
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![BU of 4au0 by Molmil](/molmil-images/mine/4au0) | Hypocrea jecorina Cel6A D221A mutant soaked with 6-chloro-4- methylumbelliferyl-beta-cellobioside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-7-hydroxy-4-methyl-2H-chromen-2-one, EXOGLUCANASE 2, ... | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | Deposit date: | 2012-05-11 | Release date: | 2013-01-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases. FEBS J., 280, 2013
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1OCB
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![BU of 1ocb by Molmil](/molmil-images/mine/1ocb) | Structure of the wild-type cellobiohydrolase Cel6A from Humicolas insolens in complex with a fluorescent substrate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-amino-4-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-methyl 4-thio-beta-D-glucopyranoside, CELLOBIOHYDROLASE II, ... | Authors: | Varrot, A, Frandsen, T.P, Von Ossowski, I, Boyer, V, Driguez, H, Schulein, M, Davies, G.J. | Deposit date: | 2003-02-07 | Release date: | 2003-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis for Ligand Binding and Processivity in Cellobiohydrolase Cel6A from Humicola Insolens Structure, 11, 2003
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1GZ1
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![BU of 1gz1 by Molmil](/molmil-images/mine/1gz1) | Mutant D416A of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA INSOLENS in complex with methyl-cellobiosyl-4-deoxy-4-thio-beta-D-cellobioside | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE II, SODIUM ION, ... | Authors: | Varrot, A, Frandsen, T, Driguez, H, Davies, G.J. | Deposit date: | 2002-05-13 | Release date: | 2003-02-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Humicola Insolens Cellobiohydrolase Cel6A D416A Mutant in Complex with a Non-Hydrolysable Substrate Analogue, Methyl Cellobiosyl-4-Thio-Beta-Cellobioside, at 1.9 A Acta Crystallogr.,Sect.D, 58, 2002
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1QJW
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![BU of 1qjw by Molmil](/molmil-images/mine/1qjw) | CEL6A (Y169F) WITH A NON-HYDROLYSABLE CELLOTETRAOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), ... | Authors: | Zou, J.-Y, Jones, T.A. | Deposit date: | 1999-07-06 | Release date: | 1999-09-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei Structure, 7, 1999
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1BVW
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![BU of 1bvw by Molmil](/molmil-images/mine/1bvw) | CELLOBIOHYDROLASE II (CEL6A) FROM HUMICOLA INSOLENS | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MAGNESIUM ION, ... | Authors: | Varrot, A, Davies, G.J, Schulein, M. | Deposit date: | 1998-09-19 | Release date: | 1999-09-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Crystal structure of the catalytic core domain of the family 6 cellobiohydrolase II, Cel6A, from Humicola insolens, at 1.92 A resolution. Biochem.J., 337, 1999
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1QK2
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![BU of 1qk2 by Molmil](/molmil-images/mine/1qk2) | WILD TYPE CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside, ... | Authors: | Zou, J.-Y, Jones, T.A. | Deposit date: | 1999-07-09 | Release date: | 1999-09-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei Structure, 7, 1999
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1CB2
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![BU of 1cb2 by Molmil](/molmil-images/mine/1cb2) | CELLOBIOHYDROLASE II, CATALYTIC DOMAIN, MUTANT Y169F | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE II, alpha-D-mannopyranose | Authors: | Kleywegt, G.J, Szardenings, M, Jones, T.A. | Deposit date: | 1995-11-25 | Release date: | 1996-10-14 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The active site of Trichoderma reesei cellobiohydrolase II: the role of tyrosine 169. Protein Eng., 9, 1996
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3CBH
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![BU of 3cbh by Molmil](/molmil-images/mine/3cbh) | |
1HGW
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![BU of 1hgw by Molmil](/molmil-images/mine/1hgw) | CEL6A D175A mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), COBALT (II) ION, ... | Authors: | Zou, J.-Y, Jones, T.A. | Deposit date: | 2000-12-15 | Release date: | 2002-01-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Active Site of Cellobiohydrolase Cel6A from Trichoderma Reesei: The Roles of Aspartic Acids D221 and D175 J.Am.Chem.Soc., 124, 2002
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1QK0
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![BU of 1qk0 by Molmil](/molmil-images/mine/1qk0) | CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-IODO-BENZYL ALCOHOL, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), ... | Authors: | Zou, J.-Y, Jones, T.A. | Deposit date: | 1999-07-08 | Release date: | 1999-09-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei Structure, 7, 1999
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1HGY
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![BU of 1hgy by Molmil](/molmil-images/mine/1hgy) | CEL6A D221A mutant | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), alpha-D-glucopyranose, ... | Authors: | Zou, J.-Y, Kleywegt, G.J, Jones, T.A. | Deposit date: | 2000-12-15 | Release date: | 2002-01-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Active Site of Cellobiohydrolase Cel6A from Trichoderma Reesei: The Roles of Aspartic Acids D221 and D175 J.Am.Chem.Soc., 124, 2002
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4AX6
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![BU of 4ax6 by Molmil](/molmil-images/mine/4ax6) | HYPOCREA JECORINA CEL6A D221A MUTANT SOAKED WITH 6-CHLORO-4- PHENYLUMBELLIFERYL-BETA-CELLOBIOSIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloranyl-7-oxidanyl-4-phenyl-chromen-2-one, EXOGLUCANASE 2, ... | Authors: | Wu, M, Nerinckx, W, Piens, K, Ishida, T, Hansson, H, Stahlberg, J, Sandgren, M. | Deposit date: | 2012-06-10 | Release date: | 2013-01-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rational Design, Synthesis, Evaluation and Enzyme-Substrate Structures of Improved Fluorogenic Substrates for Family 6 Glycoside Hydrolases. FEBS J., 280, 2013
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