PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

HIV Protease (PR) with TL-3 in the active site and (Z)-N-(thiazol-2-yl)-N'-tosylcarbamimidate in the exosite
Descriptor:	4-methyl-N-(thiazol-2-ylcarbamoyl)benzenesulfonamide, Protease, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate
Authors:	Tiefenbrunn, T, Stout, C.D.
Deposit date:	2017-03-31
Release date:	2018-04-18
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Fragment-based campaign for the identification of potential exosite binders of HIV-1 Protease to be published

HIV Protease (PR) dimer in closed form with pepstatin in active site and fragment AK-2097 in the outside/top of flap
Descriptor:	3-(morpholin-4-ylmethyl)-1H-indole-6-carboxylic acid, GLYCEROL, HIV Protease, ...
Authors:	Tiefenbrunn, T, Kislukhin, A, Finn, M.G, Stout, C.D.
Deposit date:	2014-06-26
Release date:	2014-09-24
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (2.18 Å)
Cite:	Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease. J.Phys.Chem.B, 119, 2015

HIV Protease (PR) dimer in closed form with TL-3 in active site and fragment AK-2097 in the outside/top of flap
Descriptor:	3-(morpholin-4-ylmethyl)-1H-indole-6-carboxylic acid, BETA-MERCAPTOETHANOL, Protease, ...
Authors:	Tiefenbrunn, T, Kislukhin, A, Finn, M.G, Stout, C.D.
Deposit date:	2014-06-26
Release date:	2014-09-17
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.195 Å)
Cite:	Distinguishing Binders from False Positives by Free Energy Calculations: Fragment Screening Against the Flap Site of HIV Protease. J.Phys.Chem.B, 119, 2015