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PDB: 2 results

Crystal Structure of Clostridium perfringens beta-glucuronidase
Descriptor:	Beta-glucuronidase, Maltose-binding periplasmic protein
Authors:	Wallace, B.D, Redinbo, M.R.
Deposit date:	2013-03-09
Release date:	2014-09-17
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.263 Å)
Cite:	Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chem.Biol., 22, 2015

Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine
Descriptor:	4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine, Beta-glucuronidase, Maltose/maltodextrin-binding periplasmic protein
Authors:	Wallace, B.D, Redinbo, M.R.
Deposit date:	2018-04-04
Release date:	2019-04-17
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Targeted inhibition of gut bacterial beta-glucuronidase activity enhances anticancer drug efficacy. Proc.Natl.Acad.Sci.USA, 2020