8GFA
 
 | | Cryo-EM structure of human TRPV1 in complex with the analgesic drug SB-366791 | | Descriptor: | (2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, ... | | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | | Deposit date: | 2023-03-07 | | Release date: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (2.29 Å) | | Cite: | Human TRPV1 structure and inhibition by the analgesic SB-366791.
Nat Commun, 14, 2023
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8GF9
 | | Cryo-EM structure of human TRPV1 in cNW11 nanodisc and POPC:POPE:POPG lipids | | Descriptor: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... | | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | | Deposit date: | 2023-03-07 | | Release date: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (2.58 Å) | | Cite: | Human TRPV1 structure and inhibition by the analgesic SB-366791.
Nat Commun, 14, 2023
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8GF8
 | | Cryo-EM structure of human TRPV1 in cNW11 nanodisc and soybean lipids | | Descriptor: | (2R)-3-{[(R)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctadecanoate, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, ... | | Authors: | Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. | | Deposit date: | 2023-03-07 | | Release date: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Human TRPV1 structure and inhibition by the analgesic SB-366791.
Nat Commun, 14, 2023
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6L93
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