6SLR
 
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9AXG
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4V2O
 | | Structure of saposin B in complex with chloroquine | | Descriptor: | N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B | | Authors: | Zubieta, C, Lai, X, Doyle, R.P. | | Deposit date: | 2014-10-13 | | Release date: | 2015-12-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | The Lysosomal Protein Saposin B Binds Chloroquine.
Chemmedchem, 11, 2016
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2JSA
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2JS9
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1L9L
 | | GRANULYSIN FROM HUMAN CYTOLYTIC T LYMPHOCYTES | | Descriptor: | 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ETHANOL, Granulysin, ... | | Authors: | Anderson, D.H, Sawaya, M.R, Cascio, D, Ernst, W, Krensky, A, Modlin, R, Eisenberg, D. | | Deposit date: | 2002-03-25 | | Release date: | 2002-11-06 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (0.92 Å) | | Cite: | Granulysin Crystal Structure and a Structure-Derived Lytic Mechanism
J.Mol.Biol., 325, 2002
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6VZ0
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1N69
 | | Crystal structure of human saposin B | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, SAPOSIN B | | Authors: | Ahn, V.E, Faull, K.F, Whitelegge, J.P, Fluharty, A.L, Prive, G.G. | | Deposit date: | 2002-11-08 | | Release date: | 2003-01-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of saposin B reveals a dimeric shell for lipid binding
Proc.Natl.Acad.Sci.USA, 100, 2003
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6VZE
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1OF9
 | | Solution structure of the pore forming toxin of entamoeba histolytica (Amoebapore A) | | Descriptor: | PORE-FORMING PEPTIDE AMEOBAPORE A | | Authors: | Hecht, O, Schleinkofer, K, Bruhn, H, Leippe, M, Van Nuland, N, Dingley, A.J, Grotzinger, J. | | Deposit date: | 2003-04-09 | | Release date: | 2004-02-26 | | Last modified: | 2024-10-16 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the Pore-Forming Protein of Entamoeba Histolytica
J.Biol.Chem., 279, 2004
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7MBK
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7P4T
 | | Tetrameric structure of murine SapA | | Descriptor: | Saposin-A | | Authors: | Shamin, M, Deane, J.E. | | Deposit date: | 2021-07-13 | | Release date: | 2022-05-25 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins.
Contact, 4, 2021
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2Z9A
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8EQU
 | | Structure of SARS-CoV-2 Orf3a in late endosome/lysosome-like environment, Saposin A nanodisc | | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ORF3a protein, Saposin A, ... | | Authors: | Miller, A.N, Houlihan, P.R, Matamala, E, Cabezas-Bratesco, D, Lee, G.Y, Cristofori-Armstrong, B, Dilan, T.L, Sanchez-Martinez, S, Matthies, D, Yan, R, Yu, Z, Ren, D, Brauchi, S.E, Clapham, D.E. | | Deposit date: | 2022-10-09 | | Release date: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.
Elife, 12, 2023
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3RFI
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9I63
 | | Synthetic Human Saposin D glycoprotein | | Descriptor: | Prosaposin, SULFATE ION | | Authors: | Weyand, M, Unverzagt, C. | | Deposit date: | 2025-01-29 | | Release date: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Synthetic Glycoforms Reveal Carbohydrate-Dependent Bioactivity of Human Saposin D.
Angew.Chem.Int.Ed.Engl., 56, 2017
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2DOB
 | | Crystal Structure of Human Saposin A | | Descriptor: | CALCIUM ION, Proactivator polypeptide | | Authors: | Prive, G.G, Ahn, V.E. | | Deposit date: | 2006-04-28 | | Release date: | 2006-07-25 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of saposins A and C.
Protein Sci., 15, 2006
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4DDJ
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3BQQ
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1SN6
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9AVS
 | | Human alpha-galactosidase A in complex with saposin B | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, ... | | Authors: | Sawyer, T.K, Garman, S.C. | | Deposit date: | 2024-03-04 | | Release date: | 2024-04-17 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3.53 Å) | | Cite: | Human Saposin B Ligand Binding and Presentation to alpha-Galactosidase A.
Biorxiv, 2024
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4UEX
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3BQP
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2GTG
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2QYP
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