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PDB: 10 results
6O84
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BU of 6o84 by Molmil
Cryo-EM structure of OTOP3 from xenopus tropicalis
Descriptor: LOC100127796 protein,LOC100127796 protein,OTOP3,LOC100127796 protein,LOC100127796 protein
Authors:Chen, Q.F, Bai, X.C, Jiang, Y.X.
Deposit date:2019-03-08
Release date:2019-04-24
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Structural and functional characterization of an otopetrin family proton channel.
Elife, 8, 2019
9MFM
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BU of 9mfm by Molmil
Structure of zebrafish OTOP1 in nanodisc in complex with inhibitor C2.36
Descriptor: 4-[(4R)-5H,11H-[1,2,4]triazolo[3,4-c][1,4]benzoxazepin-3-yl]phenol, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ...
Authors:Burendei, B, Ward, A.B.
Deposit date:2024-12-10
Release date:2025-11-05
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface.
Nat Commun, 16, 2025
9MFF
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BU of 9mff by Molmil
Structure of zebrafish OTOP1 in nanodisc in complex with inhibitor C2.2
Descriptor: 4-methyl-N-{2-[(2-methylprop-2-en-1-yl)oxy]phenyl}-1H-imidazole-5-carboxamide, CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, ...
Authors:Burendei, B, Ward, A.B.
Deposit date:2024-12-09
Release date:2025-11-05
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface.
Nat Commun, 16, 2025
9MFL
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BU of 9mfl by Molmil
Structure of zebrafish OTOP1 in nanodisc in the presence of inhibitor C11
Descriptor: (3beta,5beta,14beta,17alpha)-cholestan-3-ol, CHOLESTEROL HEMISUCCINATE, Proton channel OTOP1
Authors:Burendei, B, Ward, A.B.
Deposit date:2024-12-10
Release date:2025-11-05
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structure-guided discovery of Otopetrin 1 inhibitors reveals druggable binding sites at the intrasubunit interface.
Nat Commun, 16, 2025
8UG5
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BU of 8ug5 by Molmil
Caenorhabditis elegans Otopetrin 8 (CeOtop8) in pH 5.0
Descriptor: Otopetrin-2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UGA
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BU of 8uga by Molmil
Mus musculus Otopetrin 2 (mOTOP2) M374W in pH 8.0
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG7
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BU of 8ug7 by Molmil
Mus musculus Otopetrin 2 (mOTOP2) in pH 8.0
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG8
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BU of 8ug8 by Molmil
Mus musculus Otopetrin 2 (mOTOP2) in pH 7.0, intermediate state
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (3.79 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG6
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BU of 8ug6 by Molmil
Mus musculus Otopetrin 2 (mOTOP2) in pH 5.0
Descriptor: Proton channel OTOP2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024
8UG4
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BU of 8ug4 by Molmil
Caenorhabditis elegans Otopetrin 8 (CeOtop8) in pH 8.0
Descriptor: Otopetrin-2
Authors:Gan, N, Jiang, Y.
Deposit date:2023-10-05
Release date:2024-08-21
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural mechanism of proton conduction in otopetrin proton channel.
Nat Commun, 15, 2024

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