3ZVK
 
 | | Crystal structure of VapBC2 from Rickettsia felis bound to a DNA fragment from their promoter | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTITOXIN OF TOXIN-ANTITOXIN SYSTEM VAPB, DNA, ... | | Authors: | Mate, M.J, Ortiz-Lombardia, M, Cambillau, C. | | Deposit date: | 2011-07-25 | | Release date: | 2011-12-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the DNA-Bound Vapbc2 Antitoxin/Toxin Pair from Rickettsia Felis.
Nucleic Acids Res., 40, 2012
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6NKL
 | | 2.2 A resolution structure of VapBC-1 from nontypeable Haemophilus influenzae | | Descriptor: | Antitoxin VapB1, Ribonuclease VapC | | Authors: | Lovell, S, Kashipathy, M.M, Battaile, K.P, Molinaro, A.L, Daines, D.A. | | Deposit date: | 2019-01-07 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection.
J.Bacteriol., 201, 2019
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2BSQ
 | | FitAB bound to DNA | | Descriptor: | IR36, FORWARD STRAND, REVERSE STRAND, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2005-05-23 | | Release date: | 2006-08-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of Fitab from Neisseria Gonorrhoeae Bound to DNA Reveals a Tetramer of Toxin-Antitoxin Heterodimers Containing Pin Domains and Ribbon-Helix-Helix Motifs.
J.Biol.Chem., 281, 2006
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7BY2
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7BY3
 | | Toxin-antitoxin complex from klebsiella pneumoniae | | Descriptor: | CopG family transcriptional regulator, Ribonuclease VapC, SULFATE ION | | Authors: | Kang, S.M. | | Deposit date: | 2020-04-21 | | Release date: | 2021-04-28 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Toxin-antitoxin complex from klebsiella pneumoniae
To Be Published
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4XGQ
 | | Crystal structure of addiction module from Mycobacterial species | | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | | Deposit date: | 2015-01-02 | | Release date: | 2015-08-12 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
Nucleic Acids Res., 43, 2015
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4XGR
 | | Crystal structure of addiction module from Mycobacterial species | | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | | Deposit date: | 2015-01-02 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
Nucleic Acids Res., 43, 2015
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3DBO
 | | Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis | | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ... | | Authors: | Miallau, L, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-06-02 | | Release date: | 2008-07-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems: VapBC-5 FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 284, 2009
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2H1O
 | | Structure of FitAB bound to IR36 DNA fragment | | Descriptor: | IR36-strand 1, IR36-strand 2, Trafficking protein A, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2006-05-16 | | Release date: | 2006-09-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
J.Biol.Chem., 281, 2006
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3H87
 | | Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis | | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, IMIDAZOLE, ... | | Authors: | Min, A, Sawaya, M.R, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-04-28 | | Release date: | 2009-05-05 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2+) ion in the active site and a putative RNA-binding site.
Protein Sci., 21, 2012
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5X3T
 | | VapBC from Mycobacterium tuberculosis | | Descriptor: | Antitoxin VapB26, MAGNESIUM ION, Ribonuclease VapC26 | | Authors: | Kang, S.M, Kim, D.H, Yoon, H.J, Lee, B.J. | | Deposit date: | 2017-02-07 | | Release date: | 2017-06-07 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides.
Nucleic Acids Res., 45, 2017
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