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PDB: 33 results
4Y99
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BU of 4y99 by Molmil
Core domain of human cardiac troponin
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, Troponin C, ...
Authors:Takeda, S.
Deposit date:2015-02-17
Release date:2016-03-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Core domain of human cardiac troponin
To Be Published
1J1E
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BU of 1j1e by Molmil
Crystal structure of the 52kDa domain of human cardiac troponin in the Ca2+ saturated form
Descriptor: CALCIUM ION, Troponin C, Troponin I, ...
Authors:Takeda, S, Yamashita, A, Maeda, K, Maeda, Y.
Deposit date:2002-12-03
Release date:2003-07-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
1J1D
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BU of 1j1d by Molmil
Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form
Descriptor: CALCIUM ION, Troponin C, Troponin I, ...
Authors:Takeda, S, Yamashita, A, Maeda, K, Maeda, Y.
Deposit date:2002-12-03
Release date:2003-07-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Nature, 424, 2003
7UTI
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BU of 7uti by Molmil
ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM BOUND STATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rynkiewicz, M.J, Pavadai, E, Lehman, W.
Deposit date:2022-04-27
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments.
Biophys J, 119, 2020
7UTL
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BU of 7utl by Molmil
ALTERNATIVE MODELING OF TROPOMYOSIN IN HUMAN CARDIAC THIN FILAMENT IN THE CALCIUM FREE STATE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Rynkiewicz, M.J, Pavadai, E, Lehman, W.
Deposit date:2022-04-27
Release date:2022-09-21
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments.
Biophys J, 119, 2020
6KN7
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BU of 6kn7 by Molmil
Structure of human cardiac thin filament in the calcium free state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Fujii, T, Yamada, Y, Namba, K.
Deposit date:2019-08-03
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
Nat Commun, 11, 2020
6KN8
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BU of 6kn8 by Molmil
Structure of human cardiac thin filament in the calcium bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Fujii, T, Yamada, Y, Namba, K.
Deposit date:2019-08-03
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
Nat Commun, 11, 2020
9E2E
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BU of 9e2e by Molmil
The structure of the junction region of the wild-type murine native cardiac thin filament in Ca2+-free state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2024-10-22
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The structure of the junction region of the murine wild-type native cardiac thin filament.
To Be Published
8FMQ
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BU of 8fmq by Molmil
Complex structure of K210 deletion Troponin complex with alendronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.248 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMN
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BU of 8fmn by Molmil
Complex structure of K210 deletion Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMR
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BU of 8fmr by Molmil
Complex structure of K210 deletion Troponin complex with ibandronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.238 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMT
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BU of 8fmt by Molmil
Complex structure of TnnT-R205L Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMO
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BU of 8fmo by Molmil
Complex structure of K210 deletion Troponin complex with risedronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.612 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMP
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BU of 8fmp by Molmil
Complex structure of K210 deletion Troponin complex with pamidronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMM
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BU of 8fmm by Molmil
Complex structure of wild type Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.112 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMS
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BU of 8fms by Molmil
Complex structure of K210 deletion Troponin complex with neridronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.435 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
9MOP
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BU of 9mop by Molmil
Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound fully activated state (lower strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2024-12-26
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound fully activated state (lower strand)
To Be Published
9MOX
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BU of 9mox by Molmil
Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound partially activated state (lower strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2024-12-27
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound partially activated state (lower strand)
To Be Published
9MOU
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BU of 9mou by Molmil
Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound partially activated state (upper strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2024-12-27
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound partially activated state (upper strand)
To Be Published
9MOW
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BU of 9mow by Molmil
Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound fully activated state (upper strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2024-12-27
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure of native murine cardiac thin filament variant I79N in troponin T at pCa=5.8 in Ca2+-bound fully activated state (upper strand)
To Be Published
6KLU
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BU of 6klu by Molmil
Troponin of cardiac thin filament in high-calcium state
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Oda, T, Yanagisawa, H, Wakabayashi, T.
Deposit date:2019-07-30
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.
J.Struct.Biol., 209, 2020
6KLT
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BU of 6klt by Molmil
Troponin of cardiac thin filament in low-calcium state
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Oda, T, Yanagisawa, H, Wakabayashi, T.
Deposit date:2019-07-30
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Cryo-EM structures of cardiac thin filaments reveal the 3D architecture of troponin.
J.Struct.Biol., 209, 2020
9MO7
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BU of 9mo7 by Molmil
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound fully activated state (lower strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2024-12-25
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound fully activated state (lower strand)
To Be Published
9MO5
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BU of 9mo5 by Molmil
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound partially activated state (lower strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Risi, C.M, Galkin, V.E.
Deposit date:2024-12-25
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-bound partially activated state (lower strand)
To Be Published
9MOI
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BU of 9moi by Molmil
Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free rotated state (lower strand)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ...
Authors:Galkin, V.E, Risi, C.M.
Deposit date:2024-12-26
Release date:2025-06-04
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Structure of native murine cardiac thin filament at pCa=5.8 in Ca2+-free rotated state (lower strand)
To Be Published

 

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