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PDB: 25 results
8OM6
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BU of 8om6 by Molmil
Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
Descriptor: Fibroblast growth factor 2
Authors:Marek, M, Chaloupkova, R, de La Bourdonnaye, G.
Deposit date:2023-03-31
Release date:2024-03-06
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Crystal structure of FGF2-STAB, a stable variant of human fibroblast growth factor 2
To Be Published
8HU7
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BU of 8hu7 by Molmil
Crystal structure of FGF2-M1 mutant - D28E/C78L/C96I/S137P
Descriptor: Fibroblast growth factor 2
Authors:Jung, Y.E, Cha, S.S, An, Y.J.
Deposit date:2022-12-22
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of FGF2-M1 mutant - D28E/C78L/C96I/S137P
To Be Published
8HUE
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BU of 8hue by Molmil
Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, Fibroblast growth factor 2
Authors:Jung, Y.E, Cha, S.S, An, Y.J.
Deposit date:2022-12-23
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P
To Be Published
4OEE
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BU of 4oee by Molmil
Crystal Structure Analysis of FGF2-Disaccharide (S3I2) complex
Descriptor: 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2
Authors:Li, Y.C, Hsiao, C.D.
Deposit date:2014-01-13
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
1BFG
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BU of 1bfg by Molmil
CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Kitagawa, Y, Ago, H, Katsube, Y, Fujishima, A, Matsuura, Y.
Deposit date:1993-04-15
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of basic fibroblast growth factor at 1.6 A resolution.
J.Biochem.(Tokyo), 110, 1991
4FGF
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BU of 4fgf by Molmil
REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SULFATE ION
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
4OEG
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BU of 4oeg by Molmil
Crystal Structure Analysis of FGF2-Disaccharide (S9I2) complex
Descriptor: 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2
Authors:Li, Y.C, Hsiao, C.D.
Deposit date:2014-01-13
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
2FGF
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BU of 2fgf by Molmil
THREE-DIMENSIONAL STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR, A STRUCTURAL HOMOLOG OF INTERLEUKIN 1BETA
Descriptor: HEPARIN-BINDING GROWTH FACTOR 2 PRECURSOR, SULFATE ION
Authors:Zhang, J, Sprang, S.R.
Deposit date:1991-02-19
Release date:1992-01-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta.
Proc.Natl.Acad.Sci.USA, 88, 1991
4OEF
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BU of 4oef by Molmil
Crystal Structure Analysis of FGF2-Disaccharide (S6I2) complex
Descriptor: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Fibroblast growth factor 2
Authors:Li, Y.C, Hsiao, C.D.
Deposit date:2014-01-13
Release date:2014-07-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interactions that influence the binding of synthetic heparan sulfate based disaccharides to fibroblast growth factor-2.
Acs Chem.Biol., 9, 2014
1BAS
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BU of 1bas by Molmil
THREE-DIMENSIONAL STRUCTURES OF ACIDIC AND BASIC FIBROBLAST GROWTH FACTORS
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Chirino, A.J, Rees, D.C.
Deposit date:1992-09-29
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-dimensional structures of acidic and basic fibroblast growth factors.
Science, 251, 1991
1BFB
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BU of 1bfb by Molmil
BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN TETRAMER FRAGMENT
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, BASIC FIBROBLAST GROWTH FACTOR
Authors:Faham, S, Rees, D.C.
Deposit date:1995-12-12
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
5X1O
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BU of 5x1o by Molmil
PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Fibroblast growth factor 2
Authors:Tsao, Y.H.
Deposit date:2017-01-26
Release date:2018-03-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study
To Be Published
1BFF
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BU of 1bff by Molmil
THE 154 AMINO ACID FORM OF HUMAN BASIC FIBROBLAST GROWTH FACTOR
Descriptor: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, PHOSPHATE ION
Authors:Kastrup, J.S, Eriksson, E.S.
Deposit date:1996-12-06
Release date:1997-06-16
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of the 154-amino-acid form of recombinant human basic fibroblast growth factor. comparison with the truncated 146-amino-acid form.
Acta Crystallogr.,Sect.D, 53, 1997
1EV2
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BU of 1ev2 by Molmil
CRYSTAL STRUCTURE OF FGF2 IN COMPLEX WITH THE EXTRACELLULAR LIGAND BINDING DOMAIN OF FGF RECEPTOR 2 (FGFR2)
Descriptor: PROTEIN (FIBROBLAST GROWTH FACTOR 2), PROTEIN (FIBROBLAST GROWTH FACTOR RECEPTOR 2), SULFATE ION
Authors:Plotnikov, A.N, Hubbard, S.R, Schlessinger, J, Mohammadi, M.
Deposit date:2000-04-19
Release date:2000-05-31
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity.
Cell(Cambridge,Mass.), 101, 2000
1BFC
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BU of 1bfc by Molmil
BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, BASIC FIBROBLAST GROWTH FACTOR
Authors:Faham, S, Rees, D.C.
Deposit date:1995-12-12
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Heparin structure and interactions with basic fibroblast growth factor.
Science, 271, 1996
1FGA
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BU of 1fga by Molmil
REFINEMENT OF THE STRUCTURE OF HUMAN BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION AND ANALYSIS OF PRESUMED HEPARIN BINDING SITES BY SELENATE SUBSTITUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR, BETA-MERCAPTOETHANOL, SELENATE ION
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1993-02-26
Release date:1993-07-15
Last modified:2020-07-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein Sci., 2, 1993
1IIL
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BU of 1iil by Molmil
CRYSTAL STRUCTURE OF PRO253ARG APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2
Descriptor: FIBROBLAST GROWTH FACTOR RECEPTOR 2, HEPARIN-BINDING GROWTH FACTOR 2
Authors:Ibrahimi, O.A, Eliseenkova, A.V, Plotnikov, A.N, Ornitz, D.M, Mohammadi, M.
Deposit date:2001-04-23
Release date:2001-05-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
2BFH
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BU of 2bfh by Molmil
CRYSTAL STRUCTURE OF BASIC FIBROBLAST GROWTH FACTOR AT 1.6 ANGSTROMS RESOLUTION
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Kitagawa, Y, Ago, H, Katsube, Y, Fujishima, A, Matsuura, Y.
Deposit date:1993-08-31
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of basic fibroblast growth factor at 1.6 A resolution.
J.Biochem.(Tokyo), 110, 1991
6L4O
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BU of 6l4o by Molmil
Crystal structure of API5-FGF2 complex
Descriptor: Apoptosis inhibitor 5, Fibroblast growth factor 2
Authors:Lee, B.I, Bong, S.M.
Deposit date:2019-10-18
Release date:2020-04-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of mRNA export through API5 and nuclear FGF2 interaction.
Nucleic Acids Res., 48, 2020
1II4
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BU of 1ii4 by Molmil
CRYSTAL STRUCTURE OF SER252TRP APERT MUTANT FGF RECEPTOR 2 (FGFR2) IN COMPLEX WITH FGF2
Descriptor: FIBROBLAST GROWTH FACTOR RECEPTOR 2, HEPARIN-BINDING GROWTH FACTOR 2
Authors:Ibrahimi, O.A, Eliseenkova, A.V, Plotnikov, A.N, Ornitz, D.M, Mohammadi, M.
Deposit date:2001-04-20
Release date:2001-05-09
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
Proc.Natl.Acad.Sci.USA, 98, 2001
1CVS
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BU of 1cvs by Molmil
CRYSTAL STRUCTURE OF A DIMERIC FGF2-FGFR1 COMPLEX
Descriptor: FIBROBLAST GROWTH FACTOR 2, FIBROBLAST GROWTH FACTOR RECEPTOR 1, SULFATE ION
Authors:Plotnikov, A.N, Schlessinger, J, Hubbard, S.R, Mohammadi, M.
Deposit date:1999-08-24
Release date:2000-01-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for FGF receptor dimerization and activation.
Cell(Cambridge,Mass.), 98, 1999
1FQ9
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BU of 1fq9 by Molmil
CRYSTAL STRUCTURE OF A TERNARY FGF2-FGFR1-HEPARIN COMPLEX
Descriptor: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, FIBROBLAST GROWTH FACTOR 2, ...
Authors:Schlessinger, J, Plotnikov, A.N, Ibrahimi, O.A, Eliseenkova, A.V, Yeh, B.K, Yayon, A, Linhardt, R.J, Mohammadi, M.
Deposit date:2000-09-04
Release date:2000-09-27
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization.
Mol.Cell, 6, 2000
2M49
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BU of 2m49 by Molmil
Structural Insights into Human S100B and Basic Fibroblast Growth Factor (FGF2) Interaction
Descriptor: Fibroblast growth factor 2, Protein S100-B
Authors:Gupta, A.A, Yu, C.
Deposit date:2013-02-03
Release date:2013-12-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insights into the interaction of human S100B and basic fibroblast growth factor (FGF2): Effects on FGFR1 receptor signaling
Biochim.Biophys.Acta, 1834, 2013
1BLA
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BU of 1bla by Molmil
BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R, Seddon, A.P, Bohlen, P, Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996
1BLD
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BU of 1bld by Molmil
BASIC FIBROBLAST GROWTH FACTOR (FGF-2) MUTANT WITH CYS 78 REPLACED BY SER AND CYS 96 REPLACED BY SER, NMR
Descriptor: BASIC FIBROBLAST GROWTH FACTOR
Authors:Powers, R, Seddon, A.P, Bohlen, P, Moy, F.J.
Deposit date:1996-05-20
Release date:1996-11-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 35, 1996

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