6FFA
| FMDV Leader protease bound to substrate ISG15 | Descriptor: | GLYCEROL, Lbpro, SULFATE ION, ... | Authors: | Swatek, K.N, Pruneda, J.N, Komander, D. | Deposit date: | 2018-01-05 | Release date: | 2018-02-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4QBB
| Structure of the foot-and-mouth disease virus leader proteinase in complex with inhibitor (N~2~-[(3S)-4-({(2R)-1-[(4-CARBAMIMIDAMIDOBUTYL)AMINO]-4-METHYL-1-OXOPENTAN-2-YL}AMINO)-3-HYDROXY-4-OXOBUTANOYL]-L-ARGINYL-L-PROLINAMIDE) | Descriptor: | Leader protease, N~2~-[(3S)-4-({(2R)-1-[(4-carbamimidamidobutyl)amino]-4-methyl-1-oxopentan-2-yl}amino)-3-hydroxy-4-oxobutanoyl]-L-arginyl-L-prolinamide, PHOSPHATE ION, ... | Authors: | Grishkovskaya, I, Steinberger, J, Cencic, R, Juliano, M.A, Juliano, L, Skern, T. | Deposit date: | 2014-05-07 | Release date: | 2014-11-05 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Foot-and-mouth disease virus leader proteinase: Structural insights into the mechanism of intermolecular cleavage. Virology, 468-470C, 2014
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1QMY
| FMDV LEADER PROTEASE (LBSHORT-C51A-C133S) | Descriptor: | 1,2-ETHANEDIOL, PROTEASE | Authors: | Guarne, A, Tormo, J, Glaser, W, Skern, T, Fita, I. | Deposit date: | 1999-10-08 | Release date: | 2000-10-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and Biochemical Features Distinguish the Foot-and-Mouth Disease Virus Leader Proteinase from Other Papain-Like Enzymes J.Mol.Biol., 302, 2000
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1QQP
| FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX. | Descriptor: | 2-O-sulfo-alpha-L-gulopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-gulopyranuronic acid, PROTEIN (GENOME POLYPROTEIN) | Authors: | Fry, E.E, Lea, S.M, Jackson, T, Newman, J.W.I, Ellard, F.M, Blakemore, W.E, Abu-Ghazaleh, R, Samuel, A, King, A.M.Q, Stuart, D.I. | Deposit date: | 1999-05-20 | Release date: | 1999-06-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex. EMBO J., 18, 1999
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1QOL
| STRUCTURE OF THE FMDV LEADER PROTEASE | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, PROTEASE (NONSTRUCTURAL PROTEIN P20A) | Authors: | Guarne, A, Tormo, J, Kirchweger, R, Pfistermueller, D, Skern, T, Fita, I. | Deposit date: | 1999-11-13 | Release date: | 2000-11-10 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the Foot-and-Mouth Disease Virus Leader Protease: A Papain-Like Fold Adapted for Self-Processing and Eif4G Recognition. Embo J., 17, 1998
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2JQF
| Full Length Leader Protease of Foot and Mouth Disease Virus C51A Mutant | Descriptor: | Genome polyprotein | Authors: | Cencic, R, Mayer, C, Juliano, M.A, Juliano, L, Konrat, R, Kontaxis, G, Skern, T. | Deposit date: | 2007-06-01 | Release date: | 2007-07-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR J.Mol.Biol., 373, 2007
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2JQG
| Leader Protease | Descriptor: | Genome polyprotein | Authors: | Cencic, R, Mayer, C, Juliano, M.A, Juliano, L, Konrat, R, Kontaxis, G, Skern, T. | Deposit date: | 2007-06-01 | Release date: | 2007-07-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR J.Mol.Biol., 373, 2007
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