PDB Search results for query - Protein Data Bank Japan

PDB: 70 results

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with JKH100B
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.49 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOF

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z373768900
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-(1-ethyl-1H-pyrazol-4-yl)cyclobutanecarboxamide, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.5 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

8R0I

Pseudomonas aeruginosa FabF C164A in complex with 3-amino-N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)benzamide
Descriptor:	1,2-ETHANEDIOL, 3-azanyl-N-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)benzamide, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ...
Authors:	Yadrykhinsky, V, Brenk, R.
Deposit date:	2023-10-31
Release date:	2024-03-06
Last modified:	2024-05-08
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection. Rsc Med Chem, 15, 2024

5SOC

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1530301542
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, 4-ethyl-2-(1H-imidazol-5-yl)-1,3-thiazole, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SO6

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z26968795
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-(4-chloro-2,5-dimethoxyphenyl)acetamide, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SO9

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1622626423
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-[3-(trifluoromethyl)-1H-pyrazol-5-yl]-L-alaninamide, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SN7

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z32327641
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.52 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOA

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1613492358
Descriptor:	(2R)-4-(1H-pyrazol-1-yl)butan-2-ol, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.54 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

8CNE

Pa.FabF-C164A in complex with N-(propan-2-yl)-1H-pyrazole-3-carboxamide
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, FORMIC ACID, ...
Authors:	Georgiou, C, Brenk, R, Espeland, L.O.
Deposit date:	2023-02-22
Release date:	2024-01-10
Method:	X-RAY DIFFRACTION (1.57 Å)
Cite:	New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023

5SO7

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z219104216
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, 6-(ethylamino)pyridine-3-carbonitrile, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.57 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SN5

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z2856434897
Descriptor:	1-(2-phenylethyl)piperidine-4-carboxamide, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.57 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SN9

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z57258487
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-{[4-(dimethylamino)phenyl]methyl}-4H-1,2,4-triazol-4-amine, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.58 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SO4

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with JKH93A
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.59 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOE

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1429867185
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, 4-methoxy-1H-indole, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.59 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOB

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z2204875953
Descriptor:	(3P)-3-(2H-1,3-benzodioxol-5-yl)-1H-pyrazole, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.61 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOH

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z31432226
Descriptor:	(azepan-1-yl)(2H-1,3-benzodioxol-5-yl)methanone, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.61 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SNM

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z135439900
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N,N-diethyl-3-methyl-1,2-oxazole-5-carboxamide, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.63 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOG

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z57328997
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.63 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SOD

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1730522163
Descriptor:	1-[(2R)-8-fluoro-2-methyl-2,3-dihydro-4H-1,4-benzoxazin-4-yl]ethan-1-one, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.64 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SO8

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z85895198
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-(4-fluorobenzoyl)-N-methylglycine, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.64 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

5SNB

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1545313172
Descriptor:	(2~{S})-~{N}-(4-aminocarbonylphenyl)oxolane-2-carboxamide, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.67 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

4JPF

Structure of wild type Pseudomonas aeruginosa FabF (KASII) in Complex with ligand
Descriptor:	3-(benzoylamino)-2-hydroxybenzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, MAGNESIUM ION, ...
Authors:	Baum, B, Brenk, R, Jaenicke, E.
Deposit date:	2013-03-19
Release date:	2014-04-02
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (1.67 Å)
Cite:	Structures of Pseudomonas aeruginosa beta-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form. Acta Crystallogr F Struct Biol Commun, 71, 2015

8CN4

Pa.FabF-C164Q in complex with 5-acetamido-2-chlorobenzoic acid
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, 5-acetamido-2-chloranyl-benzoic acid, DIMETHYL SULFOXIDE, ...
Authors:	Georgiou, C, Brenk, R.
Deposit date:	2023-02-21
Release date:	2024-01-10
Method:	X-RAY DIFFRACTION (1.67 Å)
Cite:	New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023

8COU

Pa.FabF-C164Q in complex with 3-acetamido-4-methoxybenzoic acid
Descriptor:	3-acetamido-4-methoxy-benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
Authors:	Georgiou, C, Brenk, R.
Deposit date:	2023-02-28
Release date:	2024-01-10
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	New starting points for antibiotics targeting P. aeruginosa FabF discovered by crystallographic fragment screening followed by hit expansion Chemrxiv, 2023

5SO5

PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with JKH93B
Descriptor:	3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
Authors:	Brenk, R, Georgiou, C.
Deposit date:	2022-05-30
Release date:	2023-12-20
Last modified:	2024-01-10
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	PanDDA analysis group deposition Chemrxiv, 2023

12 3 >

Total results:	70
Displayed results:	25
Sorted by:	Resolution (from highest)
Other DB:	UniProt O54440\|G3XDA2