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4K9G
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1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound
Descriptor: (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one, 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one, CHLORIDE ION, ...
Authors:Crichlow, G.V, Al-Abed, Y, Lolis, E.J.
Deposit date:2013-04-19
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.
INT J ONCOL., 45, 2014

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