PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Studies Towards a Reversible EGFR C797S Triple Mutant Inhibitor Series
Descriptor:	5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine, Epidermal growth factor receptor
Authors:	Hargreaves, D.
Deposit date:	2020-09-17
Release date:	2021-04-07
Last modified:	2024-05-01
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Abstract 4451: Evaluation of the therapeutic potential of phosphine oxide pyrazole inhibitors in tumors harboring EGFR C797S mutation Cancer Res., 79, 2019

Studies Towards a Reversible EGFR C797S Triple Mutant Inhibitor Series
Descriptor:	5-chloranyl-~{N}2-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-5-(1-methylpyrazol-4-yl)phenyl]-~{N}4-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine, Epidermal growth factor receptor
Authors:	Hargreaves, D.
Deposit date:	2020-09-17
Release date:	2021-06-02
Last modified:	2024-05-01
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Abstract 4451: Evaluation of the therapeutic potential of phosphine oxide pyrazole inhibitors in tumors harboring EGFR C797S mutation Cancer Res., 79, 2019