9HDO
 
 | | The Human LINE-1 ORF2p target-primed reverse transcription complex | | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | | Authors: | Ghanim, G.E, Hu, H, Nguyen, T.H.D. | | Deposit date: | 2024-11-12 | | Release date: | 2025-03-12 | | Last modified: | 2025-05-07 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Structural mechanism of LINE-1 target-primed reverse transcription.
Science, 388, 2025
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9HDR
 | | Human LINE-1 ORF2p target-primed reverse transcription complex with EN domain resolved | | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | | Authors: | Ghanim, G.E, Hu, H, Nguyen, T.H.D. | | Deposit date: | 2024-11-12 | | Release date: | 2025-03-12 | | Last modified: | 2025-05-07 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural mechanism of LINE-1 target-primed reverse transcription.
Science, 388, 2025
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9HDQ
 | | The Human LINE-1 ORF2p target-primed reverse transcription complex with the fingers domain in an open conformation | | Descriptor: | LINE-1 retrotransposable element ORF2 protein, Target DNA strand 1, Target DNA strand 2, ... | | Authors: | Ghanim, G.E, Hu, H, Nguyen, T.H.D. | | Deposit date: | 2024-11-12 | | Release date: | 2025-03-12 | | Last modified: | 2025-05-07 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Structural mechanism of LINE-1 target-primed reverse transcription.
Science, 388, 2025
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9HDP
 | | The Human LINE-1 ORF2p target-primed reverse transcription complex with the fingers domain in a closed conformation | | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | | Authors: | Ghanim, G.E, Hu, H, Nguyen, T.H.D. | | Deposit date: | 2024-11-12 | | Release date: | 2025-03-12 | | Last modified: | 2025-05-07 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Structural mechanism of LINE-1 target-primed reverse transcription.
Science, 388, 2025
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