PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Cryo-EM structure of the C. neoformans lipid flippase Apt1-Cdc50 in the E1 state
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ...
Authors:	Duan, H.D, Li, H.
Deposit date:	2024-10-17
Release date:	2025-02-05
Method:	ELECTRON MICROSCOPY (3.27 Å)
Cite:	Butyrolactol A is a phospholipid flippase inhibitor that potentiates the bioactivity of caspofungin against resistant fungi. Biorxiv, 2025

Cryo-EM structure of the C. neoformans lipid flippase Apt1-Cdc50 bound with butyrolactol A in the E2P state
Descriptor:	(3R,4R,5S)-3,4-dihydroxy-5-[(1R,2R,3S,4S,5R,6R,8E,10E,14E,16Z)-1,2,3,4,5-pentahydroxy-6,20,20-trimethylhenicosa-8,10,14,16-tetraen-1-yl]oxolan-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Duan, H.D, Li, H.
Deposit date:	2024-10-17
Release date:	2025-02-05
Last modified:	2025-05-21
Method:	ELECTRON MICROSCOPY (2.72 Å)
Cite:	Butyrolactol A is a phospholipid flippase inhibitor that potentiates the bioactivity of caspofungin against resistant fungi. Biorxiv, 2025