8ZCS
 
 | | Crystal structure of the MBP-MCL1 complex with highly selective and potent Cyclic peptide inhibitor | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, TYR-LEU-LEU-PHE-TRP-ARG-ASP-GLU-LEU-ILE-LEU-LEU-CCJ-NH2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Li, F.W. | | Deposit date: | 2024-04-30 | | Release date: | 2025-03-19 | | Last modified: | 2025-04-02 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | De novo discovery of a molecular glue-like macrocyclic peptide that induces MCL1 homodimerization.
Proc.Natl.Acad.Sci.USA, 122, 2025
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