8ZPM
 
 | Cryo-EM strucutre of CXCR4 complexed with antagonist AMD070 | Descriptor: | (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine, CHOLESTEROL, Nb6 nanobody, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2024-05-30 | Release date: | 2025-02-26 | Last modified: | 2025-04-02 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists. Proc.Natl.Acad.Sci.USA, 122, 2025
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8ZPN
 
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8ZPL
 
 | Cryo-EM strucutre of CXCR4 complexed with antagonist HF51116 | Descriptor: | (2S)-N-[[4-[[3-(cyclohexylamino)propylamino]methyl]phenyl]methyl]-5-(diaminomethylideneamino)-2-(pyridin-2-ylmethylamino)pentanamide, CHOLESTEROL, Nb6 nanobody, ... | Authors: | Jiao, H.Z, Hu, H.L. | Deposit date: | 2024-05-30 | Release date: | 2025-02-26 | Last modified: | 2025-07-16 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists. Proc.Natl.Acad.Sci.USA, 122, 2025
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