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PDB: 3 results

8ZPM
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BU of 8zpm by Molmil
Cryo-EM strucutre of CXCR4 complexed with antagonist AMD070
Descriptor: (S)-N1-((1H-Benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine, CHOLESTEROL, Nb6 nanobody, ...
Authors:Jiao, H.Z, Hu, H.L.
Deposit date:2024-05-30
Release date:2025-02-26
Last modified:2025-04-02
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
Proc.Natl.Acad.Sci.USA, 122, 2025
8ZPN
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BU of 8zpn by Molmil
Cryo-EM strucutre of CXCR4 complexed with antagonist AMD3100
Descriptor: CHOLESTEROL, Nb6 nanobody, Plerixafor, ...
Authors:Jiao, H.Z, Hu, H.L.
Deposit date:2024-05-30
Release date:2025-02-26
Last modified:2025-04-02
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
Proc.Natl.Acad.Sci.USA, 122, 2025
8ZPL
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BU of 8zpl by Molmil
Cryo-EM strucutre of CXCR4 complexed with antagonist HF51116
Descriptor: (2S)-N-[[4-[[3-(cyclohexylamino)propylamino]methyl]phenyl]methyl]-5-(diaminomethylideneamino)-2-(pyridin-2-ylmethylamino)pentanamide, CHOLESTEROL, Nb6 nanobody, ...
Authors:Jiao, H.Z, Hu, H.L.
Deposit date:2024-05-30
Release date:2025-02-26
Last modified:2025-07-16
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.
Proc.Natl.Acad.Sci.USA, 122, 2025

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PDB entries from 2025-07-16

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