PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of FMS KINASE domain with a small molecular inhibitor, PLX3397
Descriptor:	5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Macrophage colony-stimulating factor 1 receptor
Authors:	Zhang, Y, Zhang, K, Zhang, C.
Deposit date:	2014-08-27
Release date:	2015-08-12
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.8001 Å)
Cite:	Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor. N Engl J Med, 373, 2015

Crystal structure of FMS kinase domain with a small molecular inhibitor, GLEEVEC
Descriptor:	4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Macrophage colony-stimulating factor 1 receptor
Authors:	Zhang, Y, Zhang, C.
Deposit date:	2014-08-27
Release date:	2015-08-12
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor. N Engl J Med, 373, 2015